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Prediction of the clinicopathological subtypes of breast cancer using a fisher discriminant analysis model based on radiomic features of diffusion-weighted MRI
BackgroundThe clinicopathological classification of breast cancer is proposed according to therapeutic purposes. It is simplified and can be...
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Classification of Homo sapiens gene behavior using linear discriminant analysis fused with minimum entropy map**
Classification of Homo sapiens gene behavior employing computational biology is a recent research trend. But monitoring gene activity profile and...
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Single-trial motor imagery electroencephalogram intention recognition by optimal discriminant hyperplane and interpretable discriminative rectangle mixture model
Spatial filtering is widely used in brain-computer interface (BCI) systems to augmented signal characteristics of electroencephalogram (EEG) signals....
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Mining the Mind: Linear Discriminant Analysis of MEG Source Reconstruction Time Series Supports Dynamic Changes in Deep Brain Regions During Meditation Sessions
Meditation practices have been claimed to have a positive effect on the regulation of mood and emotions for quite some time by practitioners, and in...
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Applying correlation analysis to electrode optimization in source domain
In brain computer interface-based neurorehabilitation system, a large number of electrodes may increase the difficulty of signal acquisition and the...
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Association of Left Atrial Sphericity with Risk of Stroke in Patients with Atrial Fibrillation. Sub-Analysis of the ASSAM Study
PurposeThe study was designed to evaluate the value of left atrial (LA) sphericity (LASP) in the identification of patients with atrial fibrillation...
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Multi-omics Analysis Reveals Key Gut Microbiota and Metabolites Closely Associated with Huntington’s Disease
Dysbiosis of the gut microbiota is closely associated with neurodegenerative diseases, including Huntington’s disease (HD). Gut microbiome-derived...
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Identification and Classification of Myoelectric Signal Features Related to Hand Motions
Either a hand movement or a gesture appears to be worthy of study regarding industrial requirements for operators who have to accomplish multiple...
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Multi-omics analysis reveals attenuation of cellular stress by empagliflozin in high glucose-treated human cardiomyocytes
BackgroundSodium–glucose cotransporter 2 (SGLT2) inhibitors constitute the gold standard treatment for type 2 diabetes mellitus (T2DM). Among them,...
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Integrated analysis of circulating and tissue proteomes reveals that fibronectin 1 is a potential biomarker in papillary thyroid cancer
Papillary thyroid cancer (PTC) is the most frequent subtype of thyroid cancer, but 20% of cases are indeterminate (i.e., cannot be accurately...
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Combined analysis of the proteome and metabolome provides insight into microRNA-1174 function in Aedes aegypti mosquitoes
BackgroundPathogenic viruses can be transmitted by female Aedes aegypti ( Ae. aegypti ) mosquitoes during blood-meal acquisition from vertebrates....
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Integrated multi-omics analysis reveals the positive leverage of citrus flavonoids on hindgut microbiota and host homeostasis by modulating sphingolipid metabolism in mid-lactation dairy cows consuming a high-starch diet
BackgroundModern dairy diets have shifted from being forage-based to grain and energy dense. However, feeding high-starch diets can lead to a...
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High-Throughput Combined Analysis of Saliva Microbiota and Metabolomic Profile in Chinese Periodontitis Patients: A Pilot Study
The onset and progression of periodontitis involves complicated interactions between the dysbiotic oral microbiota and disrupted host...
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Metabolomics Profiling of Di-(2-propylheptyl) Phthalate (DPHP) Biotransformation Products as Exposure Markers: Analytical Strategy and Application
Phthalates are widely used in the manufacture of plastics and personal care products, and humans are easily exposed to phthalates through the usage...
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Integrative analysis of transcriptomic and metabolomic profiles reveals enhanced arginine metabolism in androgen-independent prostate cancer cells
BackgroundProstate cancer is a common solid tumor that affects a significant number of men worldwide. Conventional androgen deprivation therapy (ADT)...
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Pangenome analysis reveals genomic variations associated with domestication traits in broomcorn millet
Broomcorn millet ( Panicum miliaceum L.) is an orphan crop with the potential to improve cereal production and quality, and ensure food security. Here...
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High-content analysis identified synergistic drug interactions between INK128, an mTOR inhibitor, and HDAC inhibitors in a non-small cell lung cancer cell line
BackgroundThe development of drug resistance is a major cause of cancer therapy failures. To inhibit drug resistance, multiple drugs are often...
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An integrated metabo-lipidomics profile of induced sputum for the identification of novel biomarkers in the differential diagnosis of asthma and COPD
BackgroundDue to their complexity and to the presence of common clinical features, differentiation between asthma and chronic obstructive pulmonary...
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MEG neural signature of sexual trauma in women veterans with PTSD
Previous research has documented the utility of synchronous neural interactions (SNI) in classifying women veterans with and without posttraumatic...
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Integrated microbiome and metabolome analysis reveals novel urinary microenvironmental signatures in interstitial cystitis/bladder pain syndrome patients
BackgroundThe pathogenesis of interstitial cystitis/bladder pain syndrome (IC/BPS) has not been elucidated, but urinary microorganisms and...
