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Delayed cartilage oligomeric matrix protein response to loading is associated with femoral cartilage composition post-ACLR
PurposeTo determine associations between immediate and delayed response of serum cartilage oligomeric matrix protein (sCOMP) to loading (i.e., 3000...
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Comparative Analysis of Hyaline Cartilage Characteristics and Chondrocyte Potential for Articular Cartilage Repair
This study aimed to compare the histological, biochemical, and mechanical characteristics of hyaline cartilage in different regions and evaluate the...
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Cartilage Regeneration
The treatment of damage to cartilage represents one of the most challenging clinical tasks due to the limited spontaneous healing and regenerative...
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Regeneration of Articular Cartilage
Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead...
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Regeneration of joint surface defects by transplantation of allogeneic cartilage: application of iPS cell-derived cartilage and immunogenicity
BackgroundBecause of its poor intrinsic repair capacity, articular cartilage seldom heals when damaged.
Main bodyRegenerative treatment is expected...
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Characteristics of Acute Cartilage Response After Mechanical Loading in Patients with Early-Mild Knee Osteoarthritis
This study determined whether the acute cartilage response, assessed by cartilage thickness and echo intensity, differs between patients with...
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Elastic, Dynamic Viscoelastic and Model-Derived Fibril-Reinforced Poroelastic Mechanical Properties of Normal and Osteoarthritic Human Femoral Condyle Cartilage
Osteoarthritis (OA) degrades articular cartilage and weakens its function. Modern fibril-reinforced poroelastic (FRPE) computational models can...
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Biomechanics of the Femoral Head Cartilage and Subchondral Trabecular Bone in Osteoporotic and Osteopenic Fractures
This study aimed to investigate the relationship between the micro structural properties of the subchondral trabecular bone (STB) and the macro...
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Shear wave ultrasound elastography for estimating cartilage stiffness: implications for early detection of osteoarthritis
Current osteoarthritis (OA) diagnosis relies on radiographic abnormalities found in later stages of the disease, posing a challenge to the treatment...
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Micro-computed Tomography-Based Collagen Orientation and Anisotropy Analysis of Rabbit Articular Cartilage
The collagen network is the highly organized backbone of articular cartilage providing tissue tensile stiffness and restricting proteoglycan...
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Tranexamic acid administered intraarticularly to the knee is safer for the articular cartilage and anterior cruciate ligament compared to intravenous administration: Histological analysis of an experimental rat model
In this study, the effects of tranexamic acid (TXA) on the knee’s articular cartilage, anterior cruciate ligament (ACL), and joint capsule were...
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Mechanical Properties of Fresh, Frozen and Vitrified Articular Cartilage
Osteochondral allograft transplantations are typically used to treat focal articular cartilage injuries where the damaged cartilage is replaced with...
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3D Bioprinting Strategies for Articular Cartilage Tissue Engineering
Articular cartilage is the avascular and aneural tissue which is the primary connective tissue covering the surface of articulating bone. Traumatic...
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Functional Assessment of Human Articular Cartilage Using Second Harmonic Generation (SHG) Imaging: A Feasibility Study
Many arthroscopic tools developed for knee joint assessment are contact-based, which is challenging for in vivo application in narrow joint spaces....
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An exploratory study to investigate the association between age, physical activity, femoral trochlear cartilage thickness and biomarkers of tissue metabolism in adult males
PurposeTo investigate the association between age, physical activity, femoral trochlear cartilage thickness and biomarkers of tissue metabolism in a...
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Sex-dependent variation in cartilage adaptation: from degeneration to regeneration
Despite acknowledgement in the scientific community of sex-based differences in cartilage biology, the implications for study design remain unclear,...
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Layered mechanical and electrical properties of porcine articular cartilage
The complex structure and composition of articular cartilage make its performance show depth-dependent characteristics, but its related parameters...
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Cartilage evaluation by ultrasonography in patients with rheumatoid arthritis: a sco** review
BackgroundThis study aimed to provide an overview of ultrasonographic cartilage evaluation in patients with rheumatoid arthritis (RA) and identify...
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Molecular mechanisms of environmental pollutant-induced cartilage damage: from developmental disorders to osteoarthritis
The objective of the present study was to review the molecular mechanisms of the adverse effects of environmental pollutants on chondrocytes and...
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Integrating bioprinting, cell therapies and drug delivery towards in vivo regeneration of cartilage, bone and osteochondral tissue
The biological and biomechanical functions of cartilage, bone and osteochondral tissue are naturally orchestrated by a complex crosstalk between...
