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Spinal Cord Injury: From MicroRNAs to Exosomal MicroRNAs
Spinal cord injury (SCI) is an unfortunate experience that may generate extensive sensory and motor disabilities due to the destruction and passing...
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Exosomal microRNAs and long noncoding RNAs: as novel biomarkers for endometriosis
Endometriosis is a gynecological inflammatory disorder characterized by the development of endometrial-like cells outside the uterine cavity. This...
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Specific expression profile of follicular fluid-derived exosomal microRNAs in patients with diminished ovarian reserve
BackgroundDiminished ovarian reserve (DOR) is defined as a reduction in ovarian reserve and oocyte quality. The pathophysiology of DOR has not been...
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Roles and mechanisms of exosomal microRNAs in viral infections
Exosomes are small extracellular vesicles with a diameter of 30-150 nm that originate from endosomes and fuse with the plasma membrane. They are...
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Stem Cell-Derived Exosomal MicroRNAs as Novel Potential Approach for Multiple Sclerosis Treatment
Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by inflammation and demyelination of CNS neurons....
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Identification of exosomal microRNAs and related hub genes associated with imatinib resistance in chronic myeloid leukemia
Chemotherapy resistance is a major obstacle in cancer therapy, and identifying novel druggable targets to reverse this phenomenon is essential. The...
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Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer
BackgroundDetecting cancer at an early stage before clinical manifestation could be an effective strategy to decrease cancer mortality. Thus,...
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Exosomal MicroRNAs as Brain Memory Devices
MicroRNAs (miRNAs) have been implicated in brain memory mechanisms. miR-9c, miR-31a, miR-305, miR-974, and miR-980 were involved in memory formation...
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The Detection of Exosomal PD-L1 in Peripheral Blood
Peripheral blood is a source for liquid biopsy, which can meet the requirements of pretreatment disease ty** to determine precise targeted therapy...
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Exosomal RNA Sequencing from Body Fluid Samples
Exosomes are microcapsules released by different types of cells. It contains DNA, RNA, proteins, and other substances. Exosomes spread in body...
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Circulating exosomal microRNAs as potential prognostic biomarkers in gastrointestinal cancers: a systematic review and meta-analysis
BackgroundRecent reports suggested that circulating exosomal microRNAs (exomiRs) may serve as non-invasive prediction biomarkers in gastrointestinal...
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Exosomal microRNAs in hepatocellular carcinoma
Hepatocellular carcinoma is one of the most common malignant tumors worldwide and the fourth leading cause of cancer-related deaths. The prognosis of...
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Differential Expression of Exosomal MicroRNAs in Neurodegenerative Diseases
Exosomes are small extracellular vesicles ranging from 30 nm to 100 nm and existing in body fluids like blood, urine, and cerebrospinal fluid....
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Promising roles of non-exosomal and exosomal non-coding RNAs in the regulatory mechanism and as diagnostic biomarkers in myocardial infarction
Non-exosomal non-coding RNAs (non-exo-ncRNAs) and exosomal ncRNAs (exo-ncRNAs) have been associated with the pathological development of myocardial...
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Exosomal microRNAs shuttling between tumor cells and macrophages: cellular interactions and novel therapeutic strategies
Extracellular vesicles secreted by tumor microenvironment (TME) cells are vital players in tumor progression through transferring nucleic acids and...
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Recent advances of exosomal circRNAs in cancer and their potential clinical applications
Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed, uninterrupted loop. The expression of circRNA differs among cell...
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Exosomal miR-17-92 Cluster from BMSCs Alleviates Apoptosis and Inflammation in Spinal Cord Injury
Spinal cord injury (SCI) involves neuronal apoptosis and axonal disruption, leading to severe motor dysfunction. Studies indicate that exosomes...
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Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments
Extracellular communication, in other words, crosstalk between cells, has a pivotal role in the survival of an organism. This communication occurs by...
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Abnormal expression profile of plasma-derived exosomal microRNAs in patients with treatment-resistant depression
Whether microRNAs (miRNAs) from plasma exosomes might be dysregulated in patients with depression, especially treatment-resistant depression (TRD),...
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MicroRNAs as Potential Biomarkers in Huntington’s Disease
MicroRNAs (miRNAs) play an essential role in many physiological processes of our body. Dysregulation of miRNAs is involved in the pathology of...