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Drug Excretion
Drug excretion involves processes responsible for physically removing a drug from the body, either unchanged or in the form of biotransformation... -
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Urinary Glucose Excretion as a Biomarker for Precision Medicine in Diabetes
Glucosuria has been recognized as a classical biomarker for poor glycemic control among individuals with diabetes. However, the development of... -
Identification of three distinct cell populations for urate excretion in human kidneys
In humans, uric acid is an end-product of purine metabolism. Urate excretion from the human kidney is tightly regulated by reabsorption and...
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Transport and Excretion of Foreign Compounds
Based on the solubilities in water, foreign compounds that humans ingest or inhale can be classified into two categories: hydrophiles (soluble in... -
Absorption, Distribution, Metabolism and Excretion of Biopharmaceutical Drug Products
Biopharmaceuticals are playing an increasing role in therapy; as a subset of therapeutics, their proportional use relative to traditional small drugs... -
Distribution, Metabolism, and Excretion of Cenobamate in Adult, Fetal, Neonatal, and Lactating Rats
Background and ObjectiveCenobamate is an antiseizure medication (ASM) approved for treatment of focal epilepsy in adults. The objective of this...
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Human metabolism and excretion kinetics of the surfactant 2,4,7,9-tetramethyl-5-decyne-4,7-diol (TMDD) after oral and dermal administration
2,4,7,9-Tetramethyl-5-decyne-4,7-diol (TMDD) is a non-ionic surfactant with a wide range of applications. TMDD is considered a high-production...
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Acute effects of empagliflozin on open-loop baroreflex function and urine glucose excretion in Goto-Kakizaki diabetic rats
Although suppression of sympathetic activity is suggested as one of the underlying mechanisms for the cardioprotective effects afforded by...
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Urinary Glucose Excretion as a Biomarker for Precision Medicine In Diabetes
Glucosuria has been recognized as a classical biomarker for poor glycemic control among individuals with diabetes. However, the development of... -