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Complex effects of testosterone level on ectoparasite load in a ground squirrel: an experimental test for the immunocompetence handicap hypothesis
BackgroundThe immunocompetence handicap hypothesis suggests that males with a higher testosterone level should be better at develo** male secondary...
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A novel colorectal cancer test combining microsatellite instability and BRAF/RAS analysis: Clinical validation and impact on Lynch syndrome screening
BackgroundLynch syndrome (LS) is under-diagnosed. UK National Institute for Health and Care Excellence guidelines recommend multistep molecular...
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Phylogeny-guided microbiome OTU-specific association test (POST)
BackgroundThe relationship between host conditions and microbiome profiles, typically characterized by operational taxonomic units (OTUs), contains...
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Comparison of anticoagulation control and outcomes between usual medical care and pharmacist-led anticoagulation service in ambulatory patients taking warfarin at tertiary hospital in Ethiopia: a quasi-experimental study
BackgroundWe aimed to compare anticoagulation control and outcomes between usual medical care (UMC) and pharmacist-led anticoagulation services...
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Early remission in multiple sclerosis is linked to altered coherence of the Cerebellar Network
BackgroundThe development of permanent disability in multiple sclerosis (MS) is highly variable among patients, and the exact mechanisms that...
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Impact of changes to the interscreening interval and faecal immunochemical test threshold in the national bowel cancer screening programme in England: results from the FIT pilot study
IntroductionThe NHS Bowel Cancer Screening Programme (BCSP) faces endoscopy capacity challenges from the COVID-19 pandemic and plans to lower the...
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High-throughput detection of parasites and ova in stool using the fully automatic digital feces analyzer, orienter model fa280
BackgroundIntestinal parasitic infections can harm health by causing malnutrition, anemia, impaired growth and cognitive development, and alterations...
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High prevalence of and factors associated with human papillomavirus infection among women attending a tertiary hospital in Gauteng Province, South Africa
BackgroundPersistent high-risk (hr) human papillomavirus (HPV) infection is a necessary cause of cervical cancer. Cervical cancer is a major public...
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Comparison of new computational methods for spatial modelling of malaria
BackgroundGeostatistical analysis of health data is increasingly used to model spatial variation in malaria prevalence, burden, and other metrics....
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Global burden and temporal trends of lower urinary tract symptoms: a systematic review and meta-analysis
BackgroundLower urinary tract symptoms (LUTS) are common complaint in urology practice and affecting the quality of life for patients. This article...
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Association of Sport Helmet Status on Concussion Presentation and Recovery in Male Collegiate Student-Athletes
Sporting helmets contain force attenuating materials which reduce traumatic head injury risk and may influence sport-related concussion (SRC)...
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Severe COVID-19 patients exhibit elevated levels of autoantibodies targeting cardiolipin and platelet glycoprotein with age: a systems biology approach
Age is a significant risk factor for the coronavirus disease 2019 (COVID-19) severity due to immunosenescence and certain age-dependent medical...
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Stromal lymphocytes are associated with upgrade of B3 breast lesions
Various histopathological, clinical and imaging parameters have been evaluated to identify a subset of women diagnosed with lesions with uncertain...
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On the efficacy of preventive toltrazuril treatments and the diagnosis of Cystoisospora suis infections in intensively raised piglets in farms from southeast Spain
This study investigated the presence and abundance of Cystoisospora suis oocysts in faecal samples from 131 one- to three-week-old pig litters...
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Towards defining morphologic parameters of normal parous and nulliparous breast tissues by artificial intelligence
BackgroundBreast terminal duct lobular units (TDLUs), the source of most breast cancer (BC) precursors, are shaped by age-related involution, a...
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Phage Immunoprecipitation Sequencing (PhIP-Seq) for Analyzing Antibody Epitope Repertoires Against Food Antigens
While thousands of food and environmental allergens have been reported, conventional methods for allergy testing typically rely on measuring...
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Record-matching of STR profiles with fragmentary genomic SNP data
In many forensic settings, identity of a DNA sample is sought from poor-quality DNA, for which the typical STR loci tabulated in forensic databases...
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Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
Patients with rheumatoid arthritis (RA) receive highly targeted biologic therapies without previous knowledge of target expression levels in the...
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Comparison of disease and economic burden between MRSA infection and MRSA colonization in a university hospital: a retrospective data integration study
BackgroundAlthough there is a growing concern and policy regarding infections or colonization caused by resistant bacteria, including...
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A prospective interventional study investigating sleep disorders prior to and during adjuvant radiotherapy for breast cancer
BackgroundMost breast cancer patients with non-metastatic disease receive adjuvant local or loco-regional radiotherapy. To be scheduled for...
