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TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice
Recent evidence of gut microbiota dysbiosis in the context of psoriasis and the increased cooccurrence of inflammatory bowel disease and psoriasis...
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Eosinophil–lymphocyte interactions in the tumor microenvironment and cancer immunotherapy
Eosinophils are important effector cells and therapeutic targets in allergic diseases. Emerging data indicate that eosinophils infiltrate a variety...
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Aiolos regulates eosinophil migration into tissues
Expression of Ikaros family transcription factor IKZF3 (Aiolos) increases during murine eosinophil lineage commitment and maturation. Herein, we...
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Reference intervals of complete blood count parameters in the adult western Sudanese population
BackgroundA complete blood count (CBC) analysis is one of the most common conventional blood tests that physicians frequently prescribe.
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Regulation of eosinophil functions by autophagy
Eosinophils are granule-containing leukocytes which develop in the bone marrow. For many years, eosinophils have been recognized as cytotoxic...
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Predictors for CD4 cell count and hemoglobin level with survival time to default for HIV positive adults under ART treatment at University of Gondar Comprehensive and Specialized Hospital, Ethiopia
BackgroundHIV/AIDS is the most known powerful risk factor for morbidity and mortality in the world. The greatest biological markers in HIV patients...
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Eosinophils and eosinophil-associated disorders: immunological, clinical, and molecular complexity
Eosinophils and their mediators play a crucial role in various reactive states such as bacterial and viral infections, chronic inflammatory...
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Symptomatic intracranial hemorrhage mediates the association between eosinophils and 90-day outcomes after mechanical thrombectomy for acute ischemic stroke
BackgroundDecreased eosinophil level is associated with poor outcomes after mechanical thrombectomy in patients with acute ischemic stroke (AIS), but...
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Blood count changes in malaria patients according to blood groups (ABO/Rh) and sickle cell trait
IntroductionIntroduction: Malaria continues to be the leading cause of hospitalization and death in Angola, a country in sub- Saharan Africa. In...
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Association of baseline neutrophil-to-eosinophil ratio with response to nivolumab plus ipilimumab in patients with metastatic renal cell carcinoma
BackgroundThe identification of biomarkers to select patients with metastatic renal cell carcinoma (mRCC) most likely to respond to combination...
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Blood Count Profiles as Biomarkers in Burns: Red Cells, Platelets, and Beyond
The search for biomarkers that help physicians in medical practice has been a topic of great interest in the last decades. Burned patients represent...
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Adenovirus vector-mediated YKL-40 shRNA attenuates eosinophil airway inflammation in a murine asthmatic model
Recent studies have revealed that YKL-40 is involved in the pathogenesis of asthma. However, its specific mechanism remains unclear. The present...
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Eosinophil-to-monocyte ratio is a potential biomarker in the prediction of functional outcome among patients with acute ischemic stroke
BackgroundIt has been shown that eosinophils are decreased and monocytes are elevated in patients with acute ischemic stroke (AIS), but the impact of...
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Causal Association of Leukocytes Count and Amyotrophic Lateral Sclerosis: a Mendelian Randomization Study
Peripheral immunity has been observed to be associated with amyotrophic lateral sclerosis (ALS) clinically, but whether there exist causal...
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Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Characterization of inflammation in chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) is an ongoing research process. To...
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Evaluation of microscopy, serology, circulating anodic antigen (CAA), and eosinophil counts for the follow-up of migrants with chronic schistosomiasis: a prospective cohort study
BackgroundAn accurate test for the diagnosis and post-treatment follow-up of patients with schistosomiasis is needed. We assessed the performance of...
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Blood Count Profiles as Biomarkers in Burns: Red Cells, Platelets, and Beyond
The search for biomarkers that help physicians in medical practice has been a topic of great interest in the last decades. Burned patients represent...
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Eosinophils in the tumor microenvironment: implications for cancer immunotherapy
Despite being an integral part of the immune response in the tumor microenvironment (TME), few studies have mechanistically elucidated eosinophil...
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Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separation
ObjectiveLittle has been reported regarding the reliability of methods for the purification of human blood eosinophils. We retrospectively reviewed...
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Prevalence of immune-related adverse events and anti-tumor efficacy following immune checkpoint inhibitor therapy in Japanese patients with various solid tumors
BackgroundWhile immune checkpoint inhibitors (ICIs) occasionally cause immune-related adverse events (irAEs) in various organs, the prevalence of...
