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Intestinal carcinogenicity screening of environmental pollutants using organoid-based cell transformation assay
The high incidence of colorectal cancer (CRC) is closely associated with environmental pollutant exposure. To identify potential intestinal...
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Towards improved screening of toxins for Parkinson’s risk
Parkinson’s disease (PD) is a chronic, progressive and disabling neurodegenerative disorder. The prevalence of PD has risen considerably over the...
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Environmental Toxicology
Environmental toxicology investigates the adverse effects caused by natural and synthetic pollutants in all living organisms of ecosystems and at all...
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AI-Driven Enhancements in Drug Screening and Optimization
The greatest challenge in drug discovery remains the high rate of attrition across the different phases of the process, which cost the industry...
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Evaluating variations in the barriers to colorectal cancer screening associated with telehealth use in rural U.S. Pacific Northwest
PurposeThe incidence and mortality rates of colorectal cancer (CRC) remain consistently high in rural populations. Telehealth can improve screening...
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Pervasive environmental chemicals impair oligodendrocyte development
Exposure to environmental chemicals can impair neurodevelopment, and oligodendrocytes may be particularly vulnerable, as their development extends...
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Exploring hematopoiesis in zebrafish using forward genetic screening
Zebrafish have emerged as a powerful animal model for investigating the genetic basis of hematopoiesis. Owing to its close genetic and developmental...
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Populational pan-ethnic screening panel enabled by deep whole genome sequencing
Birth defect is a global threat to the public health systems. Mitigating neonatal anomalies is hampered by elusive molecular mechanisms of pathogenic...
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Develo** an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies
BackgroundEarly detection of colorectal neoplasms can reduce the colorectal cancer (CRC) burden by timely intervention for high-risk individuals....
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Exhaled VOC detection in lung cancer screening: a comprehensive meta-analysis
BackgroundLung cancer (LC), characterized by high incidence and mortality rates, presents a significant challenge in oncology. Despite advancements...
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Assessing Disparities in Cervical Cancer Screening with Pap Test by Disability Types
Prior research has found that women with disabilities have often experienced disparities in receipt of cervical cancer screening. However, there is a...
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A Quantitative High-Throughput Screening Data Analysis Pipeline for Activity Profiling
The U.S. Tox21Tox21 program has developed in vitro assaysIn vitro assays to test large collections of environmental chemicals in a quantitative...
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Methods for the Analysis of Multiple Epigenomic Mediators in Environmental Epidemiology
Purpose of ReviewEpigenetic changes can be highly influenced by environmental factors and have in turn been proposed to influence chronic disease....
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Tobacco Control and Lung Cancer Screening to Address Disparities
Health promotion and disease prevention behaviors play an important role in cancer risk and outcomes. In particular, cigarette smoking is one of the...
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Evaluating changes to home bowel cancer screening kits: an end-user perspective study
PurposeMany people do not participate in mail-out bowel cancer screening programs due to difficulties using the screening kit. The current study...
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Fabrication of Luminescent Microtiterplate Using Terbium Complex for Phenol Screening in Seawater Samples
Tb(III)-2-aminoterphthalate complex Tb 2 -(ATPh) 3 was synthesized and characterized using FT-IR, thermal analysis and elemental analysis. Tb 2 (ATPh) 3 ...
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Disparities in Cervical Cancer Screening by Disability Types: a Systematic Review
Previous studies showed that the receipt of cervical cancer screening among women with disabilities is low. Some disparities may also exist within...
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Screening of Biosurfactants
The development of various screening approaches which are rapid, as well as reliable, and selection of a population of microorganisms as efficient...
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Equitable implementation of lung cancer screening: avoiding its potential to mirror existing inequities among people who use tobacco
PurposeLung cancer is the leading cause of cancer death, but the advent of lung cancer screening using low-dose computed tomography offers a...
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A broad wastewater screening and clinical data surveillance for virus-related diseases in the metropolitan Detroit area in Michigan
BackgroundPeriodic bioinformatics-based screening of wastewater for assessing the diversity of potential human viral pathogens circulating in a given...
