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Japanese Encephalitis Virus-Infected Cells
RNA virus infections have been a leading cause of pandemics. Aided by global warming and increased connectivity, their threat is likely to increase... -
SARS-CoV-2-associated haemorrhagic encephalitis mimicking Herpes encephalitis
Although acute encephalopathy is quite commonly seen in patients of SARS-CoV-2 infection, encephalitis characterised by brain inflammation is...
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Evolving etiologies, comorbidities, survival, and costs of care in adult encephalitis
Encephalitis is a central nervous system disorder, often caused by infectious agents or aberrant immune responses. We investigated causes,...
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A Case of Anti-Ma2 Encephalitis Presenting with Pendular Torsional Nystagmus
Antibodies against the neuronal protein Ma2 have been reported in a peculiar form of paraneoplastic encephalitis with prominent involvement of the...
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Dynamic and static changes of amplitude of low-frequency fluctuations in anti‑N‑methyl‑D‑aspartate receptor encephalitis
BackgroundPrevious neuroimaging research has examined static local brain activity changes in patients with anti-N-methyl-d-aspartate receptor...
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Functional connectivity changes of the hippocampal subregions in anti-N-methyl-D-aspartate receptor encephalitis
The hippocampus plays an important role in the pathophysiological mechanism of Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis....
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Cerebrospinal Fluid Extracellular Vesicles with Distinct Properties in Autoimmune Encephalitis and Herpes Simplex Encephalitis
Encephalitis mediated by autoantibodies against neuronal antigens and herpes simplex encephalitis (HSE) are seemingly separate causes of...
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Seronegative acute encephalitis following COVID-19 vaccines: a case series of an overlooked diagnosis with literature review
PurposeAutoimmune encephalitis is a neurological emergency of new-onset altered mental status, caused by an exaggerated immune-mediated response that...
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DNA Vaccine Encoding the Artificial T-Cell Polyepitope Immunogen of Tick-Borne Encephalitis Virus
A promising approach to the development of new means for preventing infection caused by tick-borne encephalitis virus can be DNA vaccines encoding...
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Possible role of CNS microRNAs in Human Mpox virus encephalitis—a mini-review
In May 2022, a re-emerging viral pathogen belonging to the Poxviridae was first reported from the UK, and WHO confirmed the outbreak after the...
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Fighting Dengue, Chikungunya, and Japanese Encephalitis
My arbovirus career occurred in four stages, roughly 15 years each: US Army Medical Corps, University of Hawaii School of Medicine, Rockefeller... -
Clinical features, cerebrospinal fluid changes, and prognosis in Chinese patients with autoimmune encephalitis
IntroductionAutoimmune encephalitis (AE) is a rare, treatable disease of the central nervous system (CNS) caused by an antibody-related immune...
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Role of inflammatory cytokine burst in neuro-invasion of Japanese Encephalitis virus infection: an immunotherapeutic approaches
Japanese Encephalitis remains a significant global health concern, contributing to millions of deaths annually worldwide. Microglial cells, as key...
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Elevated blood and cerebrospinal fluid biomarkers of microglial activation and blood‒brain barrier disruption in anti-NMDA receptor encephalitis
BackgroundAnti-NMDA receptor (NMDAR) encephalitis is an autoimmune disease characterized by complex neuropsychiatric syndrome and cerebrospinal fluid...
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Learning from cerebrospinal fluid drug-resistant HIV escape-associated encephalitis: a case report
BackgroundIn the era of antiretroviral therapy (ART), central nervous system (CNS) complications in patients with human immunodeficiency virus (HIV)...
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Abnormal DNA methylation analysis of leucine-rich glioma-inactivated 1 antibody encephalitis reveals novel methylation-driven genes related to prognostic and clinical features
BackgroundAberrant DNA methylation occurs commonly during pathogenesis of neuroimmunological diseases and is of clinical value in various...
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Inherited IRAK-4 Deficiency in Acute Human Herpesvirus-6 Encephalitis
Human herpesvirus-6 (HHV-6) infection can rarely cause life-threatening conditions, such as encephalitis, in otherwise healthy children, with unclear...
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Human herpesvirus 7 encephalitis in an immunocompetent adult and a literature review
BackgroundHuman herpesvirus 7 (HHV-7) is a common virus that infects children early and is accompanied by lifelong latency in cells, which is easy to...
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MVA-based vaccines are protective against lethal eastern equine encephalitis virus aerosol challenge in cynomolgus macaques
MVA-based monovalent eastern equine encephalitis virus (MVA-BN-EEEV) and multivalent western, eastern, and Venezuelan equine encephalitis virus...
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Blood and CSF levels of brain-derived neurotrophic factor in patients with encephalopathy/encephalitis: a systematic review and meta-analysis
BackgroundBrain-derived neurotrophic factor (BDNF) is critical for enhancing the survival and growth of neurons and modulating the synaptic...