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Advances in alginate encapsulation of pancreatic islets for immunoprotection in type 1 diabetes
BackgroundIslet transplantation is a promising minimally invasive approach that dispenses with many challenges, especially immunological...
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Microfluidic encapsulation of enzymes and steroids within solid lipid nanoparticles
The production of solid lipid nanoparticles (SLNs) is challenging, especially when considering the incorporation of biologics. A novel in-house...
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Micellar Encapsulation of Propofol Reduces its Adsorption on Extracorporeal Membrane Oxygenator (ECMO) Circuit
Extracorporeal membrane oxygenation (ECMO) is a life-saving cardiopulmonary bypass device used on critically ill patients with refractory heart and...
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Encapsulation and release of hydrocortisone from proliposomes govern vaginal delivery
Topical preparations of hydrocortisone can be used for the anti-inflammatory treatment of the female genital area. Although the drug is a...
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Advancements in nanoscale delivery systems: optimizing intermolecular interactions for superior drug encapsulation and precision release
Nanoscale preparations, such as nanoparticles, micelles, and liposomes, are increasingly recognized in pharmaceutical technology for their high...
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Effects of Encapsulation of Caesalpinia sappan L. with Cyclodextrins for Bovine Mastitis
The main components of Caesalpinia sappan L. (CS) are brazilin and brazilein, which show high potential in pharmacologic applications. However, these...
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Gaussian processes modeling for the prediction of polymeric nanoparticle formulation design to enhance encapsulation efficiency and therapeutic efficacy
Conventional drugs have been facing various drug delivery obstacles, including first-pass metabolism for oral medications, drug degradation by...
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Effect of Alginate Microbead Encapsulation of Placental Mesenchymal Stem Cells on Their Immunomodulatory Function
In this research we have used different cytokines and progesterone to enhance the immunomodulatory capacity of placental-derived stem cells (PLSCs)...
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Calcium Ion-Sodium Alginate-Piperine-Based Microspheres: Evidence of Enhanced Encapsulation Efficiency, Bio-Adhesion, Controlled Delivery, and Oral Bioavailability of Isoniazid
Isoniazid (INH) is a first-line chemotherapeutic drug employed in the management of tuberculosis. However, its extensive first-pass metabolism,...
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Encapsulation of Allopurinol in GO/CuFe2O4/IR MOF-3 Nanocomposite and In Vivo Evaluation of Its Efficiency
BackgroundHyperuricemia is one of the most important risk factors for gout and oxidative stress conditions caused by uric acid excessive production...
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Utilization of FMOC-3F-PHE hydrogel for encapsulation of Zanthoxylum armatum and Cinnamomum camphora oil for enhancing their antibacterial activity
ObjectiveWhile essential oils have many applications in medicine, not many studies have been done in the past to address issues of active targeting,...
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Preparation of Decellularized Tissue as Dual Cell Carrier Systems: A Step Towards Facilitating Re-epithelization and Cell Encapsulation for Tracheal Reconstruction
Surgical treatment of tracheal diseases, trauma, and congenital stenosis has shown success through tracheal reconstruction coupled with palliative...
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Nanoparticulate Systems for Encapsulation of Polyphenols
Researchers are continuously searching for various sources that could provide new promising molecules for therapeutic purposes. Nature, is one source...
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Suppression of the fibrotic encapsulation of silicone implants by inhibiting the mechanical activation of pro-fibrotic TGF-β
The fibrotic encapsulation of implants involves the mechanical activation of myofibroblasts and of pro-fibrotic transforming growth factor beta 1...
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Non-covalent Encapsulation of siRNA with Cell-Penetrating Peptides
SiRNAs may act as selective and potent therapeutics, but poor deliverability in vivo is a limitation. Among the recently proposed vectors,...
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Development and Application of a Modified Method to Determine the Encapsulation Efficiency of Proteins in Polymer Matrices
A modified method to determine protein encapsulation efficiency in polymer matrices has been developed and applied to two proteins and two polymers...
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Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion
BackgroundMetal oxide nanoparticles (NPs) are increasingly used in many industrial and biomedical applications, hence their impact on occupational...
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Nano/microformulations for Bacteriophage Delivery
Encapsulation methodologies allow the protection of bacteriophages for overcoming critical environmental conditions. Moreover, they improve the...
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A Novel Drug Delivery System: the Encapsulation of Naringenin in Metal-Organic Frameworks into Liposomes
Poorly water-soluble naringenin (NAR) was selected as a model drug and loaded into the porous MOFs for the construction of NAR@ZIF-8 inclusion...
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Synergistic induction of apoptosis in lung cancer cells through co-delivery of PLGA phytol/α-bisabolol nanoparticles
This study explored the potential of poly-(lactic-co-glycolic) acid (PLGA) nanoparticles to enhance the effectiveness of anticancer treatments...
