Search
Search Results
-
Emerging Innate Immune Cells in Cancer Immunotherapy: Promises and Challenges
Immune checkpoint inhibitor (ICI)-based therapy has made an unprecedented impact on survival benefit for a subset of cancer patients; however, only a...
-
From pre-clinical to translational brain metastasis research: current challenges and emerging opportunities
Brain metastasis, characterized by poor clinical outcomes, is a devastating disease. Despite significant mechanistic and therapeutic advances in...
-
Emerging and re-emerging infectious diseases in pregnant women in an amazonian region: a large retrospective study from French Guiana
PurposeOver the past decade, the Amazon basin has faced numerous infectious epidemics. Our comprehension of the actual extent of these infections...
-
CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances
In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a promising immunotherapeutic approach to fight cancers. This...
-
New and emerging approaches to treat psychiatric disorders
Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact the lives of millions of people worldwide. Although...
-
Comparison of classic and emerging sensory methodologies
Purpose of ReviewDescriptive Analysis (DA) is the classic methodology for describing qualitatively and quantitatively food products. However, it is...
-
Atomic force microscopy in the characterization and clinical evaluation of neurological disorders: current and emerging technologies
This review examines the significant role of Atomic Force Microscopy (AFM) in neurobiological research and its emerging clinical applications in...
-
Translational opportunities and challenges of invasive electrodes for neural interfaces
Invasive brain–machine interfaces can restore motor, sensory and cognitive functions. However, their clinical adoption has been hindered by the...
-
The Emerging Role of Natural Products in Cancer Treatment
The exploration of natural products as potential agents for cancer treatment has garnered significant attention in recent years. In this...
-
Gene therapy for CNS disorders: modalities, delivery and translational challenges
Gene therapy is emerging as a powerful tool to modulate abnormal gene expression, a hallmark of most CNS disorders. The transformative potentials of...
-
Pulmonary Delivery of Emerging Antibacterials for Bacterial Lung Infections Treatment
Bacterial infections in the respiratory tract are considered as one of the major challenges to the public health worldwide. Pulmonary delivery is an...
-
An Emerging Role for Enhancer RNAs in Brain Disorders
Noncoding DNA undergoes widespread context-dependent transcription to produce noncoding RNAs. In recent decades, tremendous advances in genomics and...
-
Evolving Therapeutic Landscape of Intracerebral Hemorrhage: Emerging Cutting-Edge Advancements in Surgical Robots, Regenerative Medicine, and Neurorehabilitation Techniques
Intracerebral hemorrhage (ICH) is the most serious form of stroke and has limited available therapeutic options. As knowledge on ICH rapidly...
-
Emerging frontiers of artificial intelligence and machine learning in ischemic stroke: a comprehensive investigation of state-of-the-art methodologies, clinical applications, and unraveling challenges
At present, stroke remains the second highest cause of death globally and a leading cause of disability. From 1990 to 2019, the absolute number of...
-
From bench to bedside: current development and emerging trend of KRAS-targeted therapy
Kirsten rat sarcoma 2 viral oncogene homolog ( KRAS ) is the most frequently mutated oncogene in human cancers with mutations predominantly occurring...
-
Small interfering RNA (siRNA)-based therapeutic applications against viruses: principles, potential, and challenges
RNA has emerged as a revolutionary and important tool in the battle against emerging infectious diseases, with roles extending beyond its...
-
MRI-guided robot intervention—current state-of-the-art and new challenges
Magnetic Resonance Imaging (MRI) is now a widely used modality for providing multimodal, high-quality soft tissue contrast images with good...
-
Successes and challenges in clinical gene therapy
Despite the ups and downs in the field over three decades, the science of gene therapy has continued to advance and provide enduring treatments for...
-
Towards the future exploration of mucosal mRNA vaccines against emerging viral diseases; lessons from existing next-generation mucosal vaccine strategies
The mRNA vaccine platform has offered the greatest potential in fighting the COVID-19 pandemic owing to rapid development, effectiveness, and...
-
Strep A: challenges, opportunities, vaccine-based solutions, and economics
This collection of articles focuses on Streptococcus pyogenes (Strep A) vaccine research and innovation, with a focus on emerging efforts to...