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Elevated serum neurofilament light chain levels are associated with hepatic encephalopathy in patients with cirrhosis
Increasing evidences implicate vital role of neuronal damage in the development of hepatic encephalopathy (HE). Neurofilament light chain (NfL) is...
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The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism
RationaleThe plasma ceramide levels in Alzheimer’s disease (AD) patients are found abnormally elevated, which is related to cognitive decline.
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The Diagnostic Value of Elevated Serum miR-30d-5p in Predicting the Severity of Acute Pancreatitis
AbstractThe purpose of our study was to reveal the expression of miR-30d-5p and its function in the occurrence and development of acute pancreatitis...
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Elevated neurofilament light chain CSF/serum ratio indicates impaired CSF outflow in idiopathic intracranial hypertension
BackgroundImpaired cerebrospinal fluid (CSF) homeostasis is central to the pathogenesis of idiopathic intracranial hypertension (IIH), although the...
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Serum Occludin Levels Are Elevated in Schizophrenia: A Case-Control Study
AbstractIn this study, it was aimed to compare the serum occludin levels of patients with schizophrenia and healthy controls. There are few studies...
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Elevated Level of Small Extracellular Vesicles in the Serum of Patients With Depression, Epilepsy and Epilepsy with Depression
Abstract —Characteristics of small extracellular vesicles (sEVs) and sEVs composition are far from being well-studied for now, especially in the...
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Elevated Serum Ninjurin-1 Is Associated with a High Risk of Large Artery Atherosclerotic Acute Ischemic Stroke
Ninjurin-1 is a novel adhesion molecule which is involved in many inflammatory diseases. Functional blockage of Ninjurin-1 has exerted an...
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Eosinophilia and elevated IgE serum levels: a red flag: when your diagnosis is not a common atopic eczema or common allergy
Objective and designThe hallmark of type 2 inflammation is eosinophilia and/or high IgE serum levels, mostly in atopic dermatitis. Nevertheless, many...
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Serum Uric Acid and Metabolic Markers in Diabetes
Uric acid, an organic compound, is the end product of purine metabolism in the liver. Hyperuricemic conditions are implicated in the pathogenesis of...
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N-glycolylneuraminic acid serum biomarker levels are elevated in breast cancer patients at all stages of disease
BackgroundNormal human tissues do not express glycans terminating with the sialic acid N -glycolylneuraminic acid (Neu5Gc), yet Neu5Gc-containing...
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Detrimental Effects of Elevated Temperatures on the Structure and Activity of Phenylalanine Ammonia Lyase-Bovine Serum Albumin Mixtures and the Stabilizing Potential of Surfactant and Sugars
We propose encapsulating phenylalanine ammonia lyase (PAL)-bovine serum albumin (BSA) mixtures as potential oral therapy for the management of...
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Serum interleukin-17 A and homocysteine levels in children with autism
BackgroundAutism Spectrum Disorder (ASD) is a neurodevelopmental condition that typically emerges early in childhood. This study aimed to explore the...
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Serum Interleukin-6 Levels as a Biomarker in Trauma
The degree of injury that occurs after trauma is proportional to the exposure of trauma energy exceeding the threshold of physiological tolerance of...
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Serum Uric Acid and Metabolic Markers in Diabetes
Uric acid, an organic compound, is the end product of purine metabolism in the liver. Hyperuricemic conditions are implicated in the pathogenesis of...
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Preoperative serum CA19-9 should be routinely measured in the colorectal patients with preoperative normal serum CEA: a multicenter retrospective cohort study
ObjectiveWhether preoperative serum carbohydrate antigen 19–9 (CA19-9) is an independent prognostic factor and there are interactions of serum CA19-9...
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Serum Angiotensin II as a Biomarker in COVID-19
Angiotensin II, synthesized by the cleavage of angiotensinogen to angiotensin I by renin and then conversion to angiotensin II by the...
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Elevated α-synuclein levels inhibit mitophagic flux
The pathogenic effect of SNCA gene multiplications indicates that elevation of wild-type α-synuclein levels is sufficient to cause Parkinson’s...
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Elevated Calcium after Acute Ischemic Stroke Predicts Severity and Prognosis
The aim of this study is to investigate whether there is a correlation between serum calcium levels and clinical severity or functional outcome at...
