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MR-Conditional Actuations: A Review
Magnetic resonance imaging (MRI) is one of the most prevailing technologies to enable noninvasive and radiation-free soft tissue imaging. Operating a...
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Mechatronic Devices for Upper Limb Tremor
Pathological tremor, such as parkinsonian and essential tremor, can significantly affect the quality of life of the individuals who suffer from it....
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3D and 4D Bioprinting Technologies: A Game Changer for the Biomedical Sector?
Bioprinting is an innovative and emerging technology of additive manufacturing (AM) and has revolutionized the biomedical sector by printing...
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Characterizing the supraspinal sensorimotor control of walking using MRI-compatible system: a systematic review
BackgroundThe regulation of gait is critical to many activities of everyday life. When walking, somatosensory information obtained from...
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Light-Based Neuronal Circuit Probing in Living Brains at High Resolution: Constraints and Layouts for Integrating Neuronal Activity Recording and Modulation in Three Dimensions
Understanding how the brain orchestrates neuronal activity to finely produce and regulate behavior is an intriguing yet challenging task. In the last...
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The-state-of-the-art of soft robotics to assist mobility: a review of physiotherapist and patient identified limitations of current lower-limb exoskeletons and the potential soft-robotic solutions
BackgroundSoft, wearable, powered exoskeletons are novel devices that may assist rehabilitation, allowing users to walk further or carry out...
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Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices
In recent year, the research of transdermal drug delivery systems has got substantial attention towards the development of microneedles (MNs). This...
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Piezoelectric Transformer-Based High-Voltage Pulse Generator Using Wide-Bandgap Semiconductors for Medical Electroporation Therapy
In this paper, a new application of Piezoelectric Transformer (PT)-based power converters to generate high-voltage (HV) bipolar pulses for medical...
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Advances in 4D printing: from stimulation to simulation
The advancement of four-dimensional (4D) printing has been fueled by the rise in demand for additive manufacturing and the expansion in shape-memory...
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Bioprinting for Therapeutics
The pharmaceutical sector is fueled by novel, high-value products that result from research and development. We can all agree that the pharmaceutical...
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A review of motor neural system robotic modeling approaches and instruments
In this review, we are considering an actively develo** tool in neuroscience—robotic modeling. The new perspective and existing application fields,...
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Isolation and Purification of Various Mammalian Cells: Single Cell Isolation
A typical adult mammalian body consists of 30–40 trillion cells. Mammalian cells differ in their shape, size, morphology, and other structural and...
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Nitinol actuated soft structures towards transnasal drug delivery: a pilot cadaver study
Sudden hearing loss can be treated noninvasively by administering drugs to the middle ear (≈1 ml) via the eustachian tube. The nasopharyngeal cavity...
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Strategies, Challenges, and Advancement in Immobilizing Silver Nanomaterials
Silver nanoparticles have been widely studied for their distinct optoelectronic properties as well as their potent antimicrobial behavior. While...
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Addressing the Need for Controls on Particle Bounce and Re-entrainment in the Cascade Impactor and for the Mitigation of Electrostatic Charge for Aerodynamic Particle Size Assessment of Orally Inhaled Products: an Assessment by the International Consortium on Regulation and Science (IPAC-RS)
Multi-stage cascade impactors (CI) are accepted for the determination of metrics of the drug mass aerodynamic particle size distributions (APSD) of...
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Green Nanoparticles: A Hope for Targeted Delivery of Natural Therapeuticals for the Management of Glioblastoma Multiforme (GBM)
Every year, large populations of primary malignant brain tumors are reported, of which approximately 70% are malignant gliomas. Over half of...
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Developments and Control of Biocompatible Conducting Polymer for Intracorporeal Continuum Robots
Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the...
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Pharmacogenomic phase transition from personalized medicine to patient-centric customized delivery
Personalized medicine has been a booming area in clinical research for the past decade, in which the detailed information about the patient genotype...
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Experimental comparisons of passive and powered ankle-foot orthoses in individuals with limb reconstruction
BackgroundAnkle-foot orthoses (AFO) are commonly prescribed to provide functional assistance for patients with lower limb injuries or weakness. Their...
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Optogenetics: Novel Brain Interface Technology That Originates in Bioprospecting
Optogenetics is a brain stimulation technique in which the activity of stimulable cells, such as neurons or astrocytes, is modulated by exposing...