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Adult Social Relationships in Primates
Like other animals, primates tend to live in social groups where they communicate with one another and interact in both agonistic and affiliative...
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Effect of Human Adenovirus Type 35 Concentration on Its Inactivation and Sorption on Titanium Dioxide Nanoparticles
Removal of pathogenic viruses from water resources is critically important for sanitation and public health. Nanotechnology is a promising technology...
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Structure-activity relationships and pharmacokinetic evaluation of L-cystine diamides as L-cystine crystallization inhibitors for cystinuria
Cystinuria is a rare genetic disorder characterized by defective l -cystine reabsorption from the renal proximal tubule, resulting in abnormally high...
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Relationships between feeding behaviors and emotions: an electroencephalogram (EEG) frequency analysis study
Feeding behaviors may be easily affected by emotions, both being based on brain activity; however, the relationships between them have not been...
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Learning Relationships Between Chemical and Physical Stability for Peptide Drug Development
Purpose or ObjectiveChemical and physical stabilities are two key features considered in pharmaceutical development. Chemical stability is typically...
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Neural Correlates of Early-Life Urbanization and Their Spatial Relationships with Gene Expression, Neurotransmitter, and Behavioral Domain Atlases
Previous neuroimaging research has established associations between urban exposure during early life and alterations in brain function and structure....
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Preliminary structure−activity relationships analysis on N-(3,5-dichlorophenyl)-4,5-dihydronaphtho[1,2-d]thiazol-2-amine, a disruptor of mycobacterial energetics
The increasing emergence of drug-resistance among mycobacteria represents a serious global health threat, requiring novel and effective therapeutic...
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In vitro structure–activity relationships and forensic case series of emerging 2-benzylbenzimidazole ‘nitazene’ opioids
2-Benzylbenzimidazole ‘nitazene’ opioids are presenting a growing threat to public health. Although various nitazenes were previously studied,...
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Serotonin Transporter (SLC6A4) and FK506-Binding Protein 5 (FKBP5) Genotype and Methylation Relationships with Response to Meditation in Veterans with PTSD
Meditation-based interventions are novel and effective non-pharmacologic treatments for veterans with PTSD. We examined relationships between...
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Relationships Among Structural Neuroimaging and Neurocognitive Outcomes in Adolescents and Young Adults with Congenital Heart Disease: A Systematic Review
Congenital heart disease (CHD) is the most common cause of major congenital anomalies in the world. Disruptions to brain development in this...
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Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome
The gut microbiome has been implicated in a variety of physiological states, but controversy over causality remains unresolved. Here, we performed...
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Life in the margins: host-parasite relationships in ecological edges
Transitional zones, such as edge habitat, are key landscapes for investigating biodiversity. “Soft edges” are permeable corridors that hosts can...
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Use of the head-twitch response to investigate the structure–activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines
Rationale4-Thio-substituted phenylalkylamines such as 2,5-dimethoxy-4-ethylthiophenethylamine (2C-T-2) and 2,5-dimethoxy-4- n -propylthiophenethylamine...
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Assessing Dose-Exposure–Response Relationships of Miltefosine in Adults and Children using Physiologically-Based Pharmacokinetic Modeling Approach
ObjectivesMiltefosine is the first and only oral medication to be successfully utilized as an antileishmanial agent. However, the drug is associated...
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Using genetic variants to evaluate the causal effect of serum vitamin D concentration on COVID-19 susceptibility, severity and hospitalization traits: a Mendelian randomization study
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has struck globally and is exerting a devastating toll on humans. The pandemic has led to...
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Curcumol: a review of its pharmacology, pharmacokinetics, drug delivery systems, structure–activity relationships, and potential applications
Curcumol (Cur), a guaiane-type sesquiterpenoid hemiketal, is an important and representative bioactive component extracted from the essential oil of...
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Parasite-host relationships of water mites (Acari: Hydrachnidia) and black flies (Diptera: Simuliidae) in southeastern Spain
BackgroundDocumentation on water mites in Spain is scarce, as is information on the parasite-host relationship between certain water mite species and...
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Relationships of multiple metals exposure, global DNA methylation, and urothelial carcinoma in central Taiwan
The relationship between heavy metal exposure and human health has been investigated mostly for individual metals, failing to consider their...
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Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosis
BackgroundToxicity assessment for regulatory purposes is starting to move away from traditional in vivo methods and towards new approach...
