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Vectorgastrogram: dynamic trajectory and recurrence quantification analysis to assess slow wave vector movement in healthy subjects
Functional gastric disorders entail chronic or recurrent symptoms, high prevalence and a significant financial burden. These disorders do not always...
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Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements
Epigenomic maps identify gene regulatory elements by their chromatin state. However, prevailing short-read sequencing methods cannot effectively...
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Design, Characterization and Biopharmaceutical Applications of Novel Green Boron-Carbon Quantum Dots for Quantification of Apalutamide; Greenness Evaluations
The diagnosis of prostate cancer has been evolving in the current decade, with expected mortality rates of 499,000 death by the year 2030....
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Standardization of a Mass Spectrometry-Based Workflow for Food Allergen Quantification
In this chapter, the analytical workflow typically used for the development and validation of an analytical method tailored to food allergen...
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Exploring recurrence quantification analysis and fractal dimension algorithms for diagnosis of encephalopathy
Electroencephalography (EEG) is a crucial non-invasive medical tool for diagnosing neurological disorder called encephalopathy. There is a...
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VIsoQLR: an interactive tool for the detection, quantification and fine-tuning of isoforms in selected genes using long-read sequencing
DNA variants altering the pre-mRNA splicing process represent an underestimated cause of human genetic diseases. Their association with disease...
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Quantification of Virion-Sense and Complementary-Sense DNA Strands of Circular Single-Stranded DNA Viruses
Circular ssDNA viruses are ubiquitous and can be found in both prokaryotes and eukaryotes. To understand the interaction of ssDNA viruses with their...
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Single-trial ERP Quantification Using Neural Networks
Traditional approaches to quantify components in event-related potentials (ERPs) are based on averaging EEG responses. However, this method ignores...
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An Innovative Selective Fluorescence Sensor for Quantification of Hazardous Food Colorant Allura Red in Beverages Using Nitrogen-Doped Carbon Quantum Dots
An innovative simple, sensitive, and selective method has been developed and validated for quantification of hazardous Allura red ( AR, E129 ) dye in...
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Dynamic chromosome association with nuclear organelles in living cells
The development of progressively sophisticated tools complemented by the integration of live cell imaging enhances our understanding of the...
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Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning
A plaque assay—the gold-standard method for measuring the concentration of replication-competent lytic virions—requires staining and usually more...
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BRWD1 orchestrates small pre-B cell chromatin topology by converting static to dynamic cohesin
Lymphocyte development consists of sequential and mutually exclusive cell states of proliferative selection and antigen receptor gene recombination....
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On the uncertainty quantification of the active uterine contraction during the second stage of labor simulation
Uterine contractions in the myometrium occur at multiple scales, spanning both organ and cellular levels. This complex biological process plays an...
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Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification
CRISPR base editing screens enable analysis of disease-associated variants at scale; however, variable efficiency and precision confounds the...
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Novel Cell Quantification Method Using a Single Surrogate Calibration Curve Across Various Biological Samples
Quantitative polymerase chain reaction (qPCR) is generally used to quantify transplanted cell therapy products in biological samples. As the matrix...
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Novel Selective Quantification of Zinpentraxin Alfa Biotherapeutic in the Presence of Endogenous Isomer in Plasma Samples of Idiopathic Pulmonary Fibrosis Patients Using Immunoaffinity LC–MS
Idiopathic pulmonary fibrosis (IPF) is a progressive fatal interstitial lung disease that affects three million patients worldwide and currently...
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Development of a TaqMan qPCR assay for trypanosomatid multi-species detection and quantification in insects
BackgroundTrypanosomatid parasites are widely distributed in nature and can have a monoxenous or dixenous life-cycle. These parasites thrive in a...
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NiftyPAD - Novel Python Package for Quantitative Analysis of Dynamic PET Data
Current PET datasets are becoming larger, thereby increasing the demand for fast and reproducible processing pipelines. This paper presents a freely...
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Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach
The recent progress in the development of in vivo biomarkers is rapidly changing how neurodegenerative diseases are conceptualized and diagnosed and...
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Temporal and spatial variability of dynamic microstate brain network in early Parkinson’s disease
Changes of brain network dynamics reveal variations in macroscopic neural activity patterns in behavioral and cognitive aspects. Quantification and...
