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Drug Distribution
Once in systemic circulation, the drug molecules will extravasate to other tissues, including the targeted organ(s), a process that we will refer to...
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Distribution In Vivo
Distribution studies with radiolabeled test substances in animals are an important part of the drug development process. Traditional routine methods...
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Distribution: Across Barriers
Distribution of drugs across barriers plays a predominant role in the processes of absorption (A), distribution (D), and excretion (E) and is thus a...
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Generative models improve fairness of medical classifiers under distribution shifts
Domain generalization is a ubiquitous challenge for machine learning in healthcare. Model performance in real-world conditions might be lower than...
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Measuring quality of facility-based ITN distribution in Ghana
BackgroundContinuous distribution channels are effective methods to deliver malaria interventions such as insecticide treated nets (ITNs) to pregnant...
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Analysis of Extracellular ATP Distribution in the Intervertebral Disc
Progressive loss of proteoglycans (PGs) is the major biochemical change during intervertebral disc (IVD) degeneration. Adenosine triphosphate (ATP)...
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Examining the effect of spatial distribution of disintegrant particles on tablet disintegratability
PurposeSuperdisintegrants are typically used at low concentrations in tablets. As a result, the spatial distribution of disintegrant particles within...
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Distribution areas and monthly dynamic distribution changes of three Aedes species in China: Aedes aegypti, Aedes albopictus and Aedes vexans
BackgroundMosquitoes play an absolute role in the spread of epidemic arbovirus diseases. Worldwide, Aedes aegypti and Aedes albopictus are the main...
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Simultaneous dose distribution and fluence prediction for nasopharyngeal carcinoma IMRT
BackgroundCurrent intensity-modulated radiation therapy (IMRT) treatment planning is still a manual and time/resource consuming task, knowledge-based...
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Genetics of sexually dimorphic adipose distribution in humans
Obesity-associated morbidity is exacerbated by abdominal obesity, which can be measured as the waist-to-hip ratio adjusted for the body mass index...
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Successful implementation of ITN distribution through health facilities in Ghana
BackgroundGlobal efforts to reduce malaria burden include distribution of insecticide-treated mosquito nets through mass campaigns and routine...
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Evaluation of Nanomedicine Tissue Distribution and Stability by Alexa Fluor 488 and PEG Immunohistochemistry
A primary issue with nanomedicine biological evaluation is determination of nanoparticle carrier tissue distribution and stability. Here we present a...
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Absorption, Distribution, Metabolism and Excretion of Biopharmaceutical Drug Products
Biopharmaceuticals are playing an increasing role in therapy; as a subset of therapeutics, their proportional use relative to traditional small drugs...
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Distribution, Metabolism, and Excretion of Cenobamate in Adult, Fetal, Neonatal, and Lactating Rats
Background and ObjectiveCenobamate is an antiseizure medication (ASM) approved for treatment of focal epilepsy in adults. The objective of this...
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Fleas of wild carnivores in Romania: diversity, distribution, and host-associations
BackgroundFleas are important hematophagous insects, infesting mammals and birds with a worldwide distribution. Fleas of medical importance have been...
