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Node-negative colon cancer: histological, molecular, and stromal features predicting disease recurrence
BackgroundWithin the group of node-negative colon cancer patients, presumed to have a good prognosis, a significant percentage of patients develops...
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Liquid biopsy for monitoring of tumor dormancy and early detection of disease recurrence in solid tumors
Cancer is one of the three leading causes of death worldwide. Even after successful therapy and achieving remission, the risk of relapse often...
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COVID-19 recurrence is related to disease-early profile T cells while detection of anti-S1 IgG is related to multifunctional T cells
COVID-19 is caused by SARS-CoV-2 infection and leads from asymptomatic to severe outcomes. The recurrence of the COVID-19 has been described,...
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Considering therapy-induced senescence as a mechanism of tumour dormancy contributing to disease recurrence
The capability of tumour cells to escape from therapy-induced senescence, as well as cell-non-autonomous functions of senescence, support the premise...
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In vivo metabolic imaging identifies lipid vulnerability in a preclinical model of Her2+/Neu breast cancer residual disease and recurrence
Recurrent cancer cells that evade therapy is a leading cause of death in breast cancer patients. This risk is high for women showing an...
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Roles of Cancer Stem Cells in Therapy Resistance and Disease Recurrence
Cancer stem cells (CSCs), which can self-renew and differentiate into different kinds of cancer cells, are suggested to be responsible for drug... -
Tumor microenvironment and immune system preservation in early-stage breast cancer: routes for early recurrence after mastectomy and treatment for lobular and ductal forms of disease
BackgroundIntra-ductal cancer (IDC) is the most common type of breast cancer, with intra-lobular cancer (ILC) coming in second. Surgery is the...
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Survival outcomes of esophageal cancer patients with recurrence after curative treatments
BackgroundLittle is known about predictive factors for survival outcomes of esophageal carcinoma (EC) patients who developed recurrence after...
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Aspirin use and head and neck cancer survival and recurrence
BackgroundHead and neck cancer (HNC) has low 5-year survival, and evidence-based recommendations for tertiary prevention are lacking. Aspirin...
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Post-recurrence survival analysis in patients with oligo-recurrence after curative esophagectomy
BackgroundRecurrent esophageal cancer is associated with dismal prognosis. There is no consensus about the role of surgical treatments in patients...
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Evaluation of dynamic recurrence risk for locally advanced gastric cancer in the clinical setting of adjuvant chemotherapy: a real-world study with IPTW-based conditional recurrence analysis
BackgroundThe long-term dynamic recurrence hazard of locally advanced gastric cancer (LAGC) in the clinical setting of adjuvant chemotherapy (ACT)...
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Integration of clinical features and deep learning on pathology for the prediction of breast cancer recurrence assays and risk of recurrence
Gene expression-based recurrence assays are strongly recommended to guide the use of chemotherapy in hormone receptor-positive, HER2-negative breast...
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A DNA methylation signature for the prediction of tumour recurrence in stage II colorectal cancer
BackgroundA major challenge in stage II colorectal carcinoma is to identify patients with increased risk of recurrence. Biomarkers that distinguish...
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Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
BackgroundRisk of recurrence and progression of ductal carcinoma in situ (DCIS) to invasive cancer remains uncertain, emphasizing the need for...
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Factors associated with recurrence in patients with oral cancer in Mongolia
IntroductionIn Mongolia, there has been limited research on the posttreatment survival rate, recurrence, and occurrence of oral cancer. The goal of...
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MR imaging phenotypes and features associated with pathogenic mutation to predict recurrence or metastasis in breast cancer
ObjectivesDistant metastasis remains the main cause of death in breast cancer. Breast cancer risk is strongly influenced by pathogenic mutation.This...
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Biomarkers in Tumor Recurrence and Metastasis
Biomolecules that are produced or secreted by tumor cells themselves or in response to tumor by other cells of body are cancer biomarkers that... -
Association of early menarche with breast tumor molecular features and recurrence
BackgroundEarly menarche is an established risk factor for breast cancer but its molecular contribution to tumor biology and prognosis remains...
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The Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer
BackgroundGlasgow Microenvironment Score (GMS) stratifies long-term survival into three groups based on tumour phenotype: peritumoural inflammation...