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1. DNA Methylation

   In this chapter, the best-understood epigenetic mark, cytosine methylation of genomic DNA, will be introduced. DNA methylation is performed by DNA...

   Carsten Carlberg, Eunike Velleuer, Ferdinand Molnár in Molecular Medicine

   Chapter 2023
   

2. DNA Methylation Analysis

   DNA methylation of promoter CpG islands silences their downstream genes, and enhancer methylation can be associated with decreased or increased gene...

   Naoko Hattori, Yu-Yu Liu, Toshikazu Ushijima in Inflammation and Cancer

   Protocol 2023
   

3. DNA Methylation

   in Dictionary of Toxicology

   Reference work entry 2024
   

4. The association between DNA methylation and human height and a prospective model of DNA methylation-based height prediction

   As a vital anthropometric characteristic, human height information not only helps to understand overall developmental status and genetic risk...

   Zhonghua Wang, Guang** Fu, ... Shu** Li in Human Genetics

   Article 20 March 2024
   

5. DNA Methylation and Epigenetic Aging Biomarkers in Huntington’s Disease

   DNA methylation is an epigenetic modification that plays critical roles in several important processes, including regulation of transcription,...

   Elizabeth A. Thomas in Biomarkers for Huntington's Disease

   Chapter 2023
   

6. DNA Methylation in Aortic Aneurysms of Different Localizations

   Abstract—

   Aortic aneurysm (AA) is a life-threatening condition, and aortic rupture that is the complication of AA in the absence of emergency surgery...

   A. N. Kucher, S. A. Shipulina, ... M. S. Nazarenko in Russian Journal of Genetics

   Article 19 June 2024

7. Degradation of methylation signals in cryopreserved DNA

   Background

   Blood-based DNA methylation has shown great promise as a biomarker in a wide variety of diseases. Studies of DNA methylation in blood often...

   Ning Yuan Lee, Melissa Hum, ... Ann S. G. Lee in Clinical Epigenetics

   Article Open access 11 September 2023
   

8. Identification of the DNA methylation signature of Mowat-Wilson syndrome

   Mowat-Wilson syndrome (MOWS) is a rare congenital disease caused by haploinsufficiency of ZEB2 , encoding a transcription factor required for...

   Stefano Giuseppe Caraffi, Liselot van der Laan, ... Livia Garavelli in European Journal of Human Genetics

   Article Open access 13 February 2024
   

9. DNA Methylation in Experimental Ischemic Brain Injury

   The enrichment of angioneurology with fundamental achievements is leading to an understanding of new important aspects of the pathogenesis of...

   N. S. Shcherbak, I. O. Suchkova, ... I. A. Voznyuk in Neuroscience and Behavioral Physiology

   Article 01 May 2023

10. DNA Methylation is Involved in Sex Determination in Spinach

    DNA methylation plays a critical role in the modulation of gene expression. The role of DNA methylation in sex determination was investigated in...

    Keli Jia, Jiaming Duan, ... Miao Hu in Biochemical Genetics

    Article 11 November 2023
    

11. DNA Methylation Imputation Across Platforms

    In this chapter, we will provide a review on imputation in the context of DNA methylation, specifically focusing on a penalized functional regression...

    Gang Li, Guosheng Zhang, Yun Li in Epigenome-Wide Association Studies

    Protocol 2022
    

12. Machine learning unveils an immune-related DNA methylation profile in germline DNA from breast cancer patients

    Background

    There is an unmet need for precise biomarkers for early non-invasive breast cancer detection. Here, we aimed to identify blood-based DNA...

    Ning Yuan Lee, Melissa Hum, ... Ann S. G. Lee in Clinical Epigenetics

    Article Open access 15 May 2024
    

13. DNA methylation and type 2 diabetes: a systematic review

    Objective

    DNA methylation influences gene expression and function in the pathophysiology of type 2 diabetes mellitus (T2DM). Map** of...

    Nikhil Nadiger, Jyothisha Kana Veed, ... Arpita Mukhopadhyay in Clinical Epigenetics

    Article Open access 16 May 2024
    

14. A systematic review on the contribution of DNA methylation to hearing loss

    Background

    DNA methylation may have a regulatory role in monogenic sensorineural hearing loss and complex, polygenic phenotypic forms of hearing loss,...

    Vibha Patil, Patricia Perez-Carpena, Jose A. Lopez-Escamez in Clinical Epigenetics

    Article Open access 05 July 2024
    

15. Aberrant DNA Methylation Profile of Dickkopf-1 in Ankylosing Spondylitis

    In recent years, the impact of methylation modifications on Dickkopf-1 (DKK1) in relation to ankylosing spondylitis (AS) has remained elusive. Our...

    **aoya Sun, Yujie Deng, ... Faming Pan in Biochemical Genetics

    Article 12 February 2024
    

16. Crosstalk between DNA methylation and hypoxia in acute myeloid leukaemia

    Background

    Acute myeloid leukaemia (AML) is a deadly disease characterised by the uncontrolled proliferation of immature myeloid cells within the bone...

    Sam Humphries, Danielle R. Bond, ... Heather J. Lee in Clinical Epigenetics

    Article Open access 13 September 2023
    

17. DNA Methylation as a Biomarker and Application to Aluminum: ADRB2 5′-Untranslated Region (5′-UTR) Methylation Level

    Environmental heavy metal exposure might be considered as a contributor to childhood asthma development and its levels of control. Moreover, heavy...

    Ola Elsayed Nafea in Biomarkers in Toxicology

    Reference work entry 2023
    

18. DNA Methylation in Pulmonary Inflammatory Diseases

    Epigenetics is genetic inheritance that is not based on DNA differences, that is, phenotypic inheritance determined by regulation of gene expression...

    Li Tang, Madhav Bhatia, **angdong Wang in Regionalized Management of Medicine

    Chapter 2022
    

19. Vpr driving DNA methylation variation of CD4 + T cells in HIV-1 infection

    Background

    Despite the existence of available therapeutic interventions for HIV-1, this virus remains a significant global threat, leading to...

    Peipei Wang, Zhuoyue Meng, ... **feng Cai in Virology Journal

    Article Open access 26 April 2024
    

20. The interaction between DNA methylation and tumor immune microenvironment: from the laboratory to clinical applications

    DNA methylation is a pivotal epigenetic modification that affects gene expression. Tumor immune microenvironment (TIME) comprises diverse immune...

    Daoqi Zhu, Siying Zeng, ... Qin Fan in Clinical Epigenetics

    Article Open access 08 February 2024