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Use of xylosidase 3C from Segatella baroniae to discriminate xylan non-reducing terminus substitution characteristics
ObjectiveNew characterized carbohydrate-active enzymes are needed for use as tools to discriminate complex carbohydrate structural features. Fungal...
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Enzyme Cascade Reactions on DNA Origami Scaffold
The protocols for constructing, characterizing, and analyzing enzyme cascade reaction systems on the DNA scaffold are described. Two-step and...
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Pectin and Pectin Derivative-Based Films
Increasing usage of synthetic packaging films has driven to significant ecological problems. Consumers are now shifting to biodegradable,...
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Synthesis of O-Linked Glycoconjugates in the Nervous System
Glycoproteins carrying O-linked N-acetylgalactosamine, N-acetylglucosamine, mannose, fucose, glucose, and xylose are found in the nervous system....
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Tumor-Associated Carbohydrate Antigens (TACA) as Novel Targets for Anticancer Therapy
Tumor-associated carbohydrate antigens (TACAs) have been described as a novel class of targets for anticancer therapy. Based on the multiple...
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Mass spectrometric analysis of chondroitin sulfate-linked peptides
Chondroitin sulfate proteoglycans (CSPGs) are extracellular matrix components composed of linear glycosaminoglycan (GAG) side chains attached to a...
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Exploitation of Marine-Derived Multifunctional Biomaterials in Biomedical Engineering and Drug Delivery
Most of Earth’s resources are found in the oceans, making marine-derived biomaterials a viable, sustainable energy source. Marine-derived materials...
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Bioactive Polysaccharides from Microalgae
Microalgae represent an untapped resource of mixed polysaccharides with potential applications in biotechnology, therapeutics, pharmaceuticals, and...
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Fucoidan-Based Nanoparticles for the Targeted Delivery of Anticancer Agents
Recently, remarkable progress has been witnessed in the nanoparticles-based delivery of anticancer agents to improve therapeutic outcomes. Various...
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A mouse model of occult intestinal colonization demonstrating antibiotic-induced outgrowth of carbapenem-resistant Enterobacteriaceae
BackgroundThe human intestinal microbiome is a complex community that contributes to host health and disease. In addition to normal microbiota,...
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Human-associated bacteria adopt an unusual route for synthesizing 3-acetylated tetramates for environmental adaptation
BackgroundTetramates or tetramic acid-containing compounds (TACs) are a group of bioactive natural products featuring a pyrrolidine-2,4-dione ring...
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Exploration of Bioactive Functional Molecules from Marine Algae: Challenges and Applications in Nutraceuticals
Marine organisms provide a rich source of chemically diverse compounds which have the potential to develop as novel therapeutic agents. Specifically,...
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Biophysical and Biochemical Characteristics of Therapeutic Proteins
Pharmaceutical proteins are large, folded structures stabilized by weak physical/chemical forces. An appreciation of the factors that may influence...
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Salmonella and Shigella
Salmonellae are ubiquitous human and animal pathogens. Salmonella spp. include Gram-negative, flagellated and facultative anaerobic bacilli...
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Introduction to the Complexity of Cell Surface and Tissue Matrix Glycoconjugates
This chapter provides an overview of structures and functions of complex carbohydrates (commonly called glycans) that are covalently linked to...
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Microalgae Polysaccharides with Potential Biomedical Application
Microalgae and cyanobacteria contain several biomolecules of commercial interest, including pigments, fatty acids, proteins, lipids, and...
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Use of Engineered Bacteria for the Production of Green Chemical and Pharmaceuticals
Microorganisms have been widely used to produce additive compounds for many applications in the food, agricultural, chemical, and pharmaceutical...
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Fucoidan-Based Nanoparticles for the Targeted Delivery of Anticancer Agents
Recently, remarkable progress has been witnessed in the nanoparticles-based delivery of anticancer agents to improve therapeutic outcomes. Various...