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Phospholipid biomarkers of coronary heart disease
Coronary heart disease, also known as ischemic heart disease, is induced by atherosclerosis, which is initiated by subendothelial retention of...
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Liquid Biopsy in Coronary Heart Disease
Cardiovascular disease (CVD) remains the major cause of morbidity and mortality globally. Accumulating evidence indicates that coronary heart disease... -
Respiratory Function of Mitochondria in Patients with Coronary Heart Disease with Implantable Cardioverter-Defibrillator
We studied the respiratory activity of mitochondria in peripheral blood leukocytes from 36 patients with coronary heart disease (CHD) and a history...
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T Helper Cells Producing Granulocyte-Macrophage Colony Stimulating Factor as a Risk Marker for Coronary Heart Disease
Coronary heart disease (CHD) is related to aberrant aggregation of immune cells in the plaques. This study focused on identification of abnormal T...
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Novel polymorphisms in CYP4A22 associated with susceptibility to coronary heart disease
BackgroundCoronary heart disease (CHD) has become a worldwide public health problem. Genetic factors are considered important risk factors for CHD....
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Chronic Coronary Artery Disease
Atherosclerosis is a chronic arterial disease and represents the first leading cause of vascular disease worldwide [1]. In addition, forecast... -
Is breathing frequency a potential means for monitoring exercise intensity in people with atrial fibrillation and coronary heart disease when heart rate is mitigated?
PurposeModerate-intensity aerobic exercise is safe and beneficial in atrial fibrillation (AF) and coronary heart disease (CHD). Irregular or rapid...
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Coronary Artery Disease Detected by Low Frequency Heart Sounds
ObjectivesPrevious studies have observed an increase in low frequency diastolic heart sounds in patients with coronary artery disease (CAD). The aim...
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Outcomes of patients with COVID-19 and coronary artery disease and heart failure: findings from the Philippine CORONA study
BackgroundPatients with coronavirus disease 2019 (COVID-19) and coronary artery disease (CAD) or heart failure (HF) are more likely to have poor...
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Analysis of the Involvement of Susceptibility Genes to Coronary Heart Disease in Implementation Signaling and Metabolic Pathways
AbstractCoronary heart disease (CHD) is a common pathology, and its development is mediated by a large number of genetic factors, environmental...
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A linear weighted combination of polygenic scores for a broad range of traits improves prediction of coronary heart disease
Polygenic scores (PGS) for coronary heart disease (CHD) are constructed using GWAS summary statistics for CHD. However, pleiotropy is pervasive in...
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Altered functional brain networks in coronary heart disease: independent component analysis and graph theoretical analysis
Coronary heart disease (CHD) confers a high risk of cognitive and mental impairments in patients. This study aimed to explore the association of CHD...
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Bioinformatic Annotation of Genes for Alzheimer’s Disease and Coronary Heart Disease
AbstractIn this work, we performed a functional annotation for genes for Alzheimer’s disease (AD) susceptibility and for coronary heart disease (CHD)...
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Causal association between major depressive disorder and coronary heart disease: a two-sample bidirectional mendelian randomization study
BackgroundMajor depressive disorder (MDD) is a highly heterogeneous mental illness and a major public health problem worldwide. A large number of...
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Enhanced Peripheral Chemoreflex Drive Is Associated with Cardiorespiratory Disorders in Mice with Coronary Heart Disease
Coronary heart disease (CHD) is a prevalent cardiovascular disease characterized by coronary artery blood flow reductions caused by lipid deposition... -
Comprehensive mendelian randomization analysis of plasma proteomics to identify new therapeutic targets for the treatment of coronary heart disease and myocardial infarction
BackgroundIschemic heart disease is one of the leading causes of mortality worldwide, and thus calls for development of more effective therapeutic...
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Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease
BackgroundDNA methylation clocks emerged as a tool to determine biological aging and have been related to mortality and age-related diseases. Little...
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Correlation Between Blood Cadmium Levels and Platelet Characteristics, As Well As Their Impact on Susceptibility to Coronary Heart Disease: Findings from NHANES 2005–2018 Data
Investigating the correlation between blood cadmium levels, platelet characteristics, and susceptibility to coronary heart disease (CHD). Utilized...
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Integrative analyses of immune-related biomarkers and associated mechanisms in coronary heart disease
Various studies showed that the effect of immune activation is pro-atherogenic and coronary heart disease (CHD) should therefore be considered an...
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Hypomethylation of ABCG1 in peripheral blood as a potential marker for the detection of coronary heart disease
BackgroundNovel molecular biomarkers for the risk assessment and early detection of coronary heart disease (CHD) are urgently needed for disease...