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Pan-cancer atlas of somatic core and linker histone mutations
Recent genomic data points to a growing role for somatic mutations altering core histone and linker histone-encoding genes in cancer. However, the...
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The Central Core of the Brain
The central core is an ovoid shaped region at the morphological center of each cerebral hemisphere and its structures display a different pattern of...
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Synthetic studies toward a simplified eleuthoside core
A concise approach to a simplified eleuthoside core is described. This synthetic pathway takes advantage of an aldol motif strategically positioned...
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Effect of core stabilization versus rebound therapy on balance in children with cerebral palsy
ObjectiveThis study aimed to compare the effect of core stabilization exercises and rebound therapy on balance in children with hemiplegic cerebral...
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Dissecting Psychiatric Heterogeneity and Comorbidity with Core Region-Based Machine Learning
Machine learning approaches are increasingly being applied to neuroimaging data from patients with psychiatric disorders to extract brain-based...
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VBCG: 20 validated bacterial core genes for phylogenomic analysis with high fidelity and resolution
BackgroundPhylogenomic analysis has become an inseparable part of studies of bacterial diversity and evolution, and many different bacterial core...
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Comparative cofactor screens show the influence of transactivation domains and core promoters on the mechanisms of transcription
Eukaryotic transcription factors (TFs) activate gene expression by recruiting cofactors to promoters. However, the relationships between TFs,...
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Characterization of Freezing Processes in Drug Substance Bottles by Ice Core Sampling
Freezing of biological drug substance (DS) is a critical unit operation that may impact product quality, potentially leading to protein aggregation...
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Nucleus accumbens core dopamine D2 receptors are required for performance of the odor span task in male rats
RationaleThe nucleus accumbens (NAc) core gates motivationally relevant behavioral action sequences through afferents from cortical and subcortical...
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Core–Shell Type Lipidic and Polymeric Nanocapsules: the Transformative Multifaceted Delivery Systems
Amongst the several nano-drug delivery systems, lipid or polymer-based core–shell nanocapsules (NCs) have garnered much attention of researchers...
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Sex differences in pre- and post-synaptic glutamate signaling in the nucleus accumbens core
BackgroundGlutamate signaling within the nucleus accumbens underlies motivated behavior and is involved in psychiatric disease. Although behavioral...
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Silk Fibroin Based Core-Shell Nanofibers Loaded with ZnO Nanoparticles: An Ideal Candidate for Designing a Medicated Wound Dressing
PurposeEfficient addressing of injuries and wounds is one of the major demands of global healthcare systems. In the present study, we optimized...
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Efficient Gamma Ray Detection Using CdTe/CdS Core/Shell Quantum Dots: A Simple and Rapid Fluorescence Approach
Gamma rays, as hazardous nuclear radiation, necessitate effective and rapid detection methods. This paper introduces a low-cost, fast, and simple...
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Development of core–shell structured nanoparticle for sequential release of tariquidar and docetaxel to overcome multi drug-resistant cancer
PurposeWe developed a core–shell (CS) nanoparticle, docetaxel (DTX)-loaded core and tariquidar (TRQ)-loaded shell conjugated with PEG and RIPL...
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Collateral Blood Flow and Ischemic Core Growth
Treatment of a large vessel occlusion in the acute ischemic stroke setting focuses on vessel recanalization, and endovascular thrombectomy results in...
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Screening of core genes prognostic for sepsis and construction of a ceRNA regulatory network
ObjectiveTo screen out core genes potentially prognostic for sepsis and construct a competing endogenous RNA (ceRNA) regulatory network.
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Core species and interactions prominent in fish-associated microbiome dynamics
BackgroundIn aquatic ecosystems, the health and performance of fish depend greatly on the dynamics of microbial community structure in the background...
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Re-Exploring the Inflammation-Related Core Genes and Modules in Cerebral Ischemia
The genetic transcription profile of brain ischemic and reperfusion injury remains elusive. To address this, we used an integrative analysis approach...
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Oxytocin treatment for core symptoms in children with autism spectrum disorder: a systematic review and meta-analysis
PurposeThe purpose of this article is to examine the efficacy of oxytocin in treating core symptoms of autism spectrum disorder (ASD) with children.
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Application of CdTe/ZnS Core/Shell Quantum Dots as on Fluorescence Sensor for Detection of Gamma Rays
Gamma rays are a type of ionizing radiation that are extremely hazardous and dangerous for humans and the environment. The fluorescence method is a...
