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Primary acute convexity subarachnoid hemorrhage in older patients: analysis of baseline, clinical and MRI characteristics including quantitative surface study and topographical probabilistic map** of convexity subarachnoid hemorrhage
ObjectivesPrimary acute convexity subarachnoid hemorrhage (cSAH) in older patients can be observed in cerebral amyloid angiopathy (CAA) or idiopathic...
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All Three Supersystems—Nervous, Vascular, and Immune—Contribute to the Cortical Infarcts After Subarachnoid Hemorrhage
The recently published DISCHARGE-1 trial supports the observations of earlier autopsy and neuroimaging studies that almost 70% of all focal brain...
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Cerebral venous sinus thrombosis presenting with subarachnoid hemorrhage: a series of 11 cases
Background and purposeCerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disease with a wide spectrum of clinical manifestations. The...
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Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age
BackgroundImpaired cerebrospinal fluid (CSF) dynamics may contribute to the pathophysiology of neurodegenerative diseases, and play a crucial role in...
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The Role of Neutrophil Extracellular Traps in Early Microthrombosis and Brain Injury After Subarachnoid Hemorrhage in Mice
Microthrombosis plays an important role in secondary brain injury after experimental subarachnoid hemorrhage (SAH), but the specific mechanism of...
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Nimodipine Attenuates Early Brain Injury by Protecting the Glymphatic System After Subarachnoid Hemorrhage in Mice
The glymphatic system (GS) plays an important role in subarachnoid hemorrhage (SAH). Nimodipine treatment provides SAH patients with short-term...
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Irreversible Neuronal Damage Begins Just After Aneurysm Rupture in Poor-Grade Subarachnoid Hemorrhage Patients
Pathophysiological findings of early brain injury in humans have not permitted conclusive determinations. We explored the essence of this phenomenon...
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Pathophysiology of reversible cerebral vasoconstriction syndrome
Reversible cerebral vasoconstriction syndrome (RCVS) is a complex neurovascular disorder being recognized during the past two decades. It is...
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Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion
BackgroundIn the cerebrospinal fluid (CSF) dynamics, the pulsations of cerebral arteries and brain is considered the main driving force for the...
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Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular injuries in cerebral large and small vessels and is a key driver of...
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General Considerations
This chapter deals with the basic neuroanatomical facts necessary to understand the human brainstem. It demonstrates the three-dimensional... -
The contribution of the meningeal immune interface to neuroinflammation in traumatic brain injury
Traumatic brain injury (TBI) is a major cause of disability and mortality worldwide, particularly among the elderly, yet our mechanistic...
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Meningioma and Other Meningeal Tumors
MeningiomasMeningiomas develop from meningothelialMeningothelial cells and approximately account for more than 30 percent of central nervous... -
Large Vessel Vasospasm Is Not Associated with Cerebral Cortical Hypoperfusion in a Murine Model of Subarachnoid Hemorrhage
Clinical studies on subarachnoid hemorrhage (SAH) have shown discrepancies between large vessel vasospasm, cerebral perfusion, and clinical outcome....
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Risk Factors for the Development of De Novo Generalized Tonic-Clonic Epileptic Seizures in Patients with Supratentorial Meningiomas after Neurosurgical Treatment
Objectives . To identify risk factors for the occurrence of de novo epileptic seizures in the early postoperative period in patients with...
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Ballooned neurons in semi-recent severe traumatic brain injury
Traumatic brain injury (TBI) is now recognized as an insult triggering a dynamic process of degeneration and regeneration potentially evolving for...
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Extensive widening of Virchow-Robin spaces in the frontal lobe: two case reports and systematic review of the literature
AimTo report our experience on giant tumefactive Virchow-Robin spaces (GTVRS) in the frontal lobe and perform a systematic review of previous reports...
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Single and simultaneous multiple intracerebral hemorrhages: a radiological review
Simultaneous multiple intracerebral hemorrhage (SMICH) is defined as ICH in two or more discrete noncontiguous acute intraparenchymal locations on...