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  1. Minimal residual disease profiling predicts pathological complete response in esophageal squamous cell carcinoma

    Accurate presurgical prediction of pathological complete response (pCR) can guide treatment decisions, potentially avoiding unnecessary surgeries and...

    Pinli Yue, Fenglong Bie, ... Shugeng Gao in Molecular Cancer
    Article Open access 10 May 2024
  2. Pathological complete response to neoadjuvant chemotherapy in triple negative breast cancer – single hospital experience

    Background

    Triple-negative breast cancer is a heterogeneous molecular subtype of BC. Pathological complete response (pCR) is an important surrogate...

    Elina Sivina, Lubova Blumberga, ... Arvids Irmejs in Hereditary Cancer in Clinical Practice
    Article Open access 16 March 2023
  3. CT-based delta-radiomics nomogram to predict pathological complete response after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma patients

    Background

    This study developed a nomogram model using CT-based delta-radiomics features and clinical factors to predict pathological complete...

    Liyuan Fan, Zhe Yang, ... Qiang Wen in Journal of Translational Medicine
    Article Open access 18 June 2024
  4. Pathological complete response, category change, and prognostic significance of HER2-low breast cancer receiving neoadjuvant treatment: a multicenter analysis of 2489 cases

    Background

    HER2-low breast cancers (BC) show a good response to novel anti-HER2 antibody-drug conjugates (ADCs) in advanced setting. Nevertheless,...

    Siji Zhu, Yujie Lu, ... **aosong Chen in British Journal of Cancer
    Article Open access 21 August 2023
  5. Identifying breast cancer patients at risk of relapse despite pathological complete response after neoadjuvant therapy

    This retrospective pooled analysis aims to identify factors predicting relapse despite a pathologic complete response (pCR) in patients with breast...

    Jens Huober, Marion van Mackelenbergh, ... Michael Untch in npj Breast Cancer
    Article Open access 07 April 2023
  6. PROACTING: predicting pathological complete response to neoadjuvant chemotherapy in breast cancer from routine diagnostic histopathology biopsies with deep learning

    Background

    Invasive breast cancer patients are increasingly being treated with neoadjuvant chemotherapy; however, only a fraction of the patients...

    Witali Aswolinskiy, Enrico Munari, ... Francesco Ciompi in Breast Cancer Research
    Article Open access 13 November 2023
  7. A nomogram based on platelet-to-lymphocyte ratio for predicting pathological complete response of breast cancer after neoadjuvant chemotherapy

    Objective

    To investigate the role of platelet-to-lymphocyte ratio (PLR) in complete pathological response (pCR) of breast cancer (BC) patients after...

    Rulan Ma, Wanzhen Wei, ... Dawei Yuan in BMC Cancer
    Article Open access 14 March 2023
  8. A combined nomogram based on radiomics and hematology to predict the pathological complete response of neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma

    Background

    To predict pathological complete response (pCR) in patients receiving neoadjuvant immunochemotherapy (nICT) for esophageal squamous cell...

    Yu Yang, Yan Yi, ... Baosheng Li in BMC Cancer
    Article Open access 12 April 2024
  9. The use of longitudinal CT-based radiomics and clinicopathological features predicts the pathological complete response of metastasized axillary lymph nodes in breast cancer

    Background

    Accurate assessment of axillary status after neoadjuvant therapy for breast cancer patients with axillary lymph node metastasis is...

    Jia Wang, Cong Tian, ... Zhen-Zhen Liu in BMC Cancer
    Article Open access 01 May 2024
  10. Machine learning prediction of pathological complete response and overall survival of breast cancer patients in an underserved inner-city population

    Background

    Generalizability of predictive models for pathological complete response (pCR) and overall survival (OS) in breast cancer patients requires...

    Kevin Dell’Aquila, Abhinav Vadlamani, ... Tim Q. Duong in Breast Cancer Research
    Article Open access 10 January 2024
  11. Early prediction of pathological complete response to neoadjuvant chemotherapy combining DCE-MRI and apparent diffusion coefficient values in breast Cancer

    Introduction

    Improving the early prediction of neoadjuvant chemotherapy (NAC) efficacy in breast cancer can lead to an improved prediction of the...

    **nhong Liang, **aofeng Chen, ... Yunuo Zhang in BMC Cancer
    Article Open access 02 December 2022
  12. Enhancing pathological complete response prediction in breast cancer: the role of dynamic characterization of DCE-MRI and its association with tumor heterogeneity

    Background

    Early prediction of pathological complete response (pCR) is important for deciding appropriate treatment strategies for patients. In this...

    **nyu Zhang, **nzhi Teng, ... **g Cai in Breast Cancer Research
    Article Open access 14 May 2024
  13. Evaluation of pathological response to neoadjuvant chemotherapy in locally advanced cervical cancer

    Neoadjuvant chemotherapy (NACT) is a viable therapeutic option for women diagnosed locally advanced cervical cancer (LACC). However, the factors...

    Li-Jun Wei, Jia Fu, ... Li-Li Liu in Journal of Translational Medicine
    Article Open access 14 July 2024
  14. A non-invasive artificial intelligence model for identifying axillary pathological complete response to neoadjuvant chemotherapy in breast cancer: a secondary analysis to multicenter clinical trial

    Background

    This study aims to develop a stacking model for accurately predicting axillary lymph node (ALN) response to neoadjuvant chemotherapy (NAC)...

    Teng Zhu, Yu-Hong Huang, ... Kun Wang in British Journal of Cancer
    Article 25 June 2024
  15. Noninvasive imaging signatures of HER2 and HR using ADC in invasive breast cancer: repeatability, reproducibility, and association with pathological complete response to neoadjuvant chemotherapy

    Background

    The immunohistochemical test (IHC) of HER2 and HR can provide prognostic information and treatment guidance for invasive breast cancer...

    **nzhi Teng, Jiang Zhang, ... **g Cai in Breast Cancer Research
    Article Open access 28 June 2023
  16. Concurrent clinical and pathological response predicts favorable prognosis of patients with gastric cancer after neoadjuvant therapy: a real-world study

    Background

    Response of locally advanced gastric cancer (LAGC) to neoadjuvant therapy (NAT) may be associated with prognosis, but which of the clinical...

    Chongyuan Sun, Penghui Niu, ... Dongbing Zhao in BMC Cancer
    Article Open access 18 October 2023
  17. Dynamic radiological features predict pathological response after neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma

    Background

    Neoadjuvant immunochemotherapy (NICT) plus esophagectomy has emerged as a promising treatment option for locally advanced esophageal...

    Yuli Ruan, Yue Ma, ... Yanqiao Zhang in Journal of Translational Medicine
    Article Open access 18 May 2024
  18. Develop and validate a radiomics space-time model to predict the pathological complete response in patients undergoing neoadjuvant treatment of rectal cancer: an artificial intelligence model study based on machine learning

    Objective

    In this study, we aimed to investigate the predictive efficacy of magnetic resonance imaging (MRI) radiomics features at different time...

    Jiaxuan Peng, Wei Wang, ... Zhenyu Shu in BMC Cancer
    Article Open access 21 April 2023
  19. An integrated deep learning model for the prediction of pathological complete response to neoadjuvant chemotherapy with serial ultrasonography in breast cancer patients: a multicentre, retrospective study

    Background

    The biological phenotype of tumours evolves during neoadjuvant chemotherapy (NAC). Accurate prediction of pathological complete response...

    Lei Wu, Weitao Ye, ... Ying Wang in Breast Cancer Research
    Article Open access 21 November 2022
  20. Development of an Interpretable Deep Learning Model for Pathological Tumor Response Assessment After Neoadjuvant Therapy

    Background

    Neoadjuvant therapy followed by surgery has become the standard of care for locally advanced esophageal squamous cell carcinoma (ESCC) and...

    Yichen Wang, Wenhua Zhang, ... Yuan Li in Biological Procedures Online
    Article Open access 17 April 2024
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