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Showing 1-20 of 5,976 results
  1. The prognostic value of circular RNA regulatory genes in competitive endogenous RNA network in gastric cancer

    Accumulating evidence shows that circular RNA (circRNA) is an important regulator of many diseases, especially cancer. Gastric cancer (GC) is a...

    Tong Han, Zonglin Chen, ... Bo Liu in Cancer Gene Therapy
    Article 29 January 2021
  2. Elucidation of endothelial progenitor cell dysfunction in diabetes by RNA sequencing and constructing lncRNA–miRNA–mRNA competing endogenous RNA network

    Abstract

    With the rapid increase in the incidence of diabetes, non-healing diabetic wounds have posed a huge challenge to public health. Endothelial...

    Gui Wan, Zhao Xu, ... Zhenbing Chen in Journal of Molecular Medicine
    Article 12 September 2022
  3. The lnc-CTSLP8 upregulates CTSL1 as a competitive endogenous RNA and promotes ovarian cancer metastasis

    Background

    Ovarian cancer is highly lethal and has a poor prognosis due to metastasis. Long non-coding RNAs (lncRNAs) are key regulators of tumor...

    **n**g Wang, **aoduan Li, ... **peng Wang in Journal of Experimental & Clinical Cancer Research
    Article Open access 01 May 2021
  4. Reconstruction of lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveals functional lncRNAs in skin cutaneous melanoma

    Background

    Human skin cutaneous melanoma is the most common and dangerous skin tumour, but its pathogenesis is still unclear. Although some progress...

    Junyou Zhu, ** Deng, ... Shaohai Qi in BMC Cancer
    Article Open access 29 September 2020
  5. Pseudogenes as Competitive Endogenous RNAs: Target Prediction and Validation

    Pseudogenes may regulate expression of their parental genes as well as other protein-coding genes through various mechanisms. One such mechanism is...
    Florian A. Karreth, Ugo Ala, ... Pier Paolo Pandolfi in Pseudogenes
    Protocol 2021
  6. Competing endogenous RNA networks related to prognosis in chronic lymphocytic leukemia: comprehensive analyses and construction of a novel risk score model

    Background

    Chronic lymphocytic leukemia (CLL) is a heterogeneous B-cell malignancy that lacks specific biomarkers and drug targets. Competing...

    **n Zhang, Yang Han, ... **n Wang in Biomarker Research
    Article Open access 21 October 2022
  7. Retraction Note: Hsa_circ_0001944 promotes the growth and metastasis in bladder cancer cells by acting as a competitive endogenous RNA for miR-548

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-020-01697-6.

    Mingming **, Shengjie Lu, ... Gang Huang in Journal of Experimental & Clinical Cancer Research
    Article Open access 24 January 2023
  8. Identification of a ZC3H12D-regulated competing endogenous RNA network for prognosis of lung adenocarcinoma at single-cell level

    Background

    To identify hub genes from the competing endogenous RNA (ceRNA) network of lung adenocarcinoma (LUAD) and to explore their potential...

    Wenhan Chen, Zhifeng Guo, ... Yiming Zeng in BMC Cancer
    Article Open access 28 January 2022
  9. Retraction Note: CircPSMC3 suppresses the proliferation and metastasis of gastric cancer by acting as a competitive endogenous RNA through sponging miR-296-5p

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12943-019-0958-6.

    Dawei Rong, Chen Lu, ... Hongyong Cao in Molecular Cancer
    Article Open access 16 January 2023
  10. Retraction Note: Long non-coding RNA AGAP2-AS1, functioning as a competitive endogenous RNA, upregulates ANXA11 expression by sponging miR-16-5p and promotes proliferation and metastasis in hepatocellular carcinoma

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-019-1188-x.

    Zhikui Liu, Yufeng Wang, ... Qingguang Liu in Journal of Experimental & Clinical Cancer Research
    Article Open access 02 November 2022
  11. Coordinated action of human papillomavirus type 16 E6 and E7 oncoproteins on competitive endogenous RNA (ceRNA) network members in primary human keratinocytes

    Background

    miRNAs and lncRNAs can regulate cellular biological processes both under physiological and pathological conditions including tumour...

    Brigitta László, László Antal, ... József Kónya in BMC Cancer
    Article Open access 07 June 2021
  12. The Long Non-Coding RNA NR3C2-8:1 Promotes p53-Mediated Apoptosis through the miR-129-5p/USP10 Axis in Amyotrophic Lateral Sclerosis

    Motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is a form of apoptosis, but the mechanisms underlying this neuronal cell death...

    Dejiang Pang, Yujiao Yu, ... Huifang Shang in Molecular Neurobiology
    Article Open access 23 February 2024
  13. Emerging role of RNA modification and long noncoding RNA interaction in cancer

    RNA modification, especially N6-methyladenosine, 5-methylcytosine, and N7-methylguanosine methylation, participates in the occurrence and progression...

    Liqiong Yang, Lu Tang, ... **g Shen in Cancer Gene Therapy
    Article Open access 14 February 2024
  14. Construction of a competitive endogenous RNA network and analysis of potential regulatory axis targets in glioblastoma

    Background

    Glioblastoma is the most common primary malignant brain tumor. Because of the limited understanding of its pathogenesis, the prognosis of...

    Kai Yu, Huan Yang, ... **ao-li Shen in Cancer Cell International
    Article Open access 12 February 2021
  15. Pseudogenes as Competitive Endogenous RNAs: Testing miRNA Dependency

    Pseudogenes may function as competitive endogenous RNAs (ceRNAs), where they regulate the expression of genes by sequestering shared miRNAs. ceRNAs...
    **aonan Xu, Florian A. Karreth in Pseudogenes
    Protocol 2021
  16. Integrative Analysis of the Expression of microRNA, Long Noncoding RNA, and mRNA in Osteoarthritis and Construction of a Competing Endogenous Network

    This study aimed to identify potential core microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and mRNAs in osteoarthritis (OA) to construct a...

    Juntan Li, **ang Gao, ... Xu Li in Biochemical Genetics
    Article 18 November 2021
  17. Construction of competitive endogenous RNA network reveals regulatory role of long non-coding RNAs in intracranial aneurysm

    Background

    Rupture of intracranial aneurysm (IA) is the main cause of devastating subarachnoid hemorrhage, which urges our understanding of the...

    Yuan-Bo Pan, Jianan Lu, ... Anwen Shao in BMC Neuroscience
    Article Open access 09 March 2021
  18. Identification of a three-long noncoding RNA prognostic model involved competitive endogenous RNA in kidney renal clear cell carcinoma

    Background

    Long noncoding RNA (lncRNA) is generally identified as competing endogenous RNA (ceRNA) that plays a vital role in the pathogenesis of...

    Di Zhang, Song Zeng, **aopeng Hu in Cancer Cell International
    Article Open access 17 July 2020
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