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Who gets prescriptions for proton pump inhibitors and why? A drug-utilization study with claims data in Bavaria, Germany, 2010–2018
PurposeThe German annual drug prescription-report has indicated overuse of proton pump inhibitors (PPIs) for many years; however, little was known...
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Co-prescription of metoprolol and CYP2D6-inhibiting antidepressants before and after implementation of an optimized drug interaction database in Norway
PurposeTo compare the co-prescription of metoprolol and potent CYP2D6-inhibiting antidepressants before and during a 10-year period after...
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Precision Medicine in Diabetes
Tailoring treatment or management to groups of individuals based on specific clinical, molecular, and genomic features is the concept of precision... -
The prevalence and clinical context of antimicrobial resistance amongst medical inpatients at a referral hospital in Rwanda: a cohort study
BackgroundAntimicrobial resistance (AMR) is a growing global concern. AMR surveillance is a crucial component of the international response;...
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Ability to detect potentially inappropriate prescribing in older patients: comparative analysis between PIM-Check and STOPP/STARTv2
PurposePotentially inappropriate prescribing (PIP) is a source of preventable adverse drug events. The objective of this study was a comparative...
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Antibody-Based Biotherapeutics in Inflammatory Diseases
Inflammatory diseases encompass a broad and diverse spectrum of serious chronic disorders, many of which have significant need for safe and effective... -
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
PurposeTo investigate real-world prescribing trends and clinical outcomes based on body mass index (BMI) categorization in patients who received...
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Economic Evidence for Pharmacist Prescribing in Community Pharmacy
The effectiveness of pharmacist interventions is supported by high-level evidence from around the world. Such effectiveness combined with high levels... -
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Current Trends and Future Directions in Urban Social Prescribing
Purpose of ReviewSocial prescribing (SP) is defined as a non-medical community referral program to support well-being and health. This review...
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Factors associated with long-term benzodiazepine and Z-drug use across the lifespan and 5-year temporal trajectories among incident users: a Swedish nationwide register-based study
PurposeDespite being discouraged by guidelines, long-term use of benzodiazepines and related Z-drugs (BZDR) remains frequent in the real-world. An...
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The impact of a summative national prescribing assessment and curriculum type on the development of the prescribing competence of junior doctors
PurposeThe primary aim of this study was to investigate the effect of including the Dutch National Pharmacotherapy Assessment (DNPA) in the medical...
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The impact of the COVID-19 pandemic on the treatment of common infections in primary care and the change to antibiotic prescribing in England
BackgroundThere is concern that the COVID-19 pandemic altered the management of common infections in primary care. This study aimed to evaluate...
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Trends in use of sodium-glucose co-transporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) in Australia in the era of increased evidence of their cardiovascular benefits (2014–2022)
PurposeTo investigate trends in SGLT2i and GLP-1RA use in Australia in the era of increased evidence of their cardiovascular benefits.
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Unveiling the Biosimilar Paradox of Oncologists’ Perceptions and Hesitations in South Korea: A Web-Based Survey Study
IntroductionBiosimilars offer a cost-effective alternative to original biopharmaceuticals with comparable efficacy and safety. The perception and...
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Patient perspectives on pharmacogenomic (PGx) testing for antidepressant prescribing in primary care: a qualitative description study
Many patients with major depressive disorder (MDD) try multiple antidepressants before finding one that works well and is tolerable. Pharmacogenomic...
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Deprescribing
Deprescribing refers to reducing or stop** medications that may no longer be needed, may be causing more harm than good, or may not align with a... -
Gamified antimicrobial decision support app (GADSA) changes antibiotics prescription behaviour in surgeons in Nigeria: a hospital-based pilot study
AimsSurgical Antibiotic Prophylaxis (SAP) in Nigeria is often not evidence based. The aim of this study is to test if the GADSA application can...
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Prescription characteristics associated with drug overdose risk among adults prescribed benzodiazepines: a cohort study
BackgroundDrug overdose (OD) deaths in the U.S. continue to rise. After opioids, benzodiazepines (BZD) are the medication most commonly involved in...