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Role of Circadian Rhythm in Hormonal Cancers
Circadian rhythm is a fundamental biological process that regulates various physiological functions in the body, including the secretion of hormones....
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Circadian rhythm of intraocular pressure
Intraocular pressure (IOP) plays a crucial role in glaucoma development, involving the dynamics of aqueous humor (AH). AH flows in from the ciliary...
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Molecular mechanisms of artificial light at night affecting circadian rhythm disturbance
Artificial light at night (ALAN) pollution has been regarded as a global environmental concern. More than 80% of the global population is exposed to...
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Sleep and Circadian Rhythm in Post-COVID-19 Patients
The current COVID-19 pandemic caused enormous suffering to people in the disease state and caused significant mortality; the morbidity of people...
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E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1
The circadian clock is the inner rhythm of life activities and is controlled by a self-sustained and endogenous molecular clock, which maintains...
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Quercetin improved hepatic circadian rhythm dysfunction in middle-aged mice fed with vitamin D-deficient diet
We aimed to determine whether quercetin is capable of improving circadian rhythm and metabolism disorder under vitamin D-deficient condition....
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Circadian Rhythm and Personalized Exercise
Almost all physiological and biochemical processes in the human body follow a circadian rhythm. Studies have found that the biological rhythms of the...
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Circadian Rhythm Measurements in Humans
The protocols for circadian rhythm measurements in humans totally depend on the purpose of the study. Since the dynamics of circadian pacemaker in...
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VX-765 Alleviates Circadian Rhythm Disorder in a Rodent Model of Traumatic Brain Injury Plus Hemorrhagic Shock and Resuscitation
Severe traumatic brain injury (TBI) can result in persistent complications, including circadian rhythm disorder, that substantially affect not only...
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CRS: a circadian rhythm score model for predicting prognosis and treatment response in cancer patients
BackgroundCircadian rhythm regulates complex physiological activities in organisms. A strong link between circadian dysfunction and cancer has been...
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Gut microbiota and circadian rhythm in Alzheimer’s disease pathophysiology: a review and hypothesis on their association
Alzheimer’s disease (AD) is the most common neurodegenerative disease and the leading cause of dementia worldwide. Different pathologic changes have...
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Disturbed circadian rhythm and retinal degeneration in a mouse model of Alzheimer’s disease
The circadian clock is synchronized to the 24 h day by environmental light which is transmitted from the retina to the suprachiasmatic nucleus (SCN)...
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Monkeypox virus replication underlying circadian rhythm networks
The mammalian brain has an endogenous central circadian clock that regulates central and peripheral cellular activities. At the molecular level, this...
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Integrated Bulk and Single-Cell RNA-Sequencing Reveals the Effects of Circadian Rhythm Disruption on the Metabolic Reprogramming of CD4+ T Cells in Alzheimer’s Disease
Although growing evidence suggests close correlations between Alzheimer’s disease (AD) and circadian rhythm disruption (CRD), few studies have...
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Identification of the Relationship Between DNA Methylation of Circadian Rhythm Genes and Obesity
In children, teenagers, and young adults, environmental factors and genetic modifications have contributed to the development of obesity. There is a...
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Study on the circadian rhythm and sleep state characteristics of patients with acute cerebral infarction accompanied by sleep-breathing disorders
There is limited research on the circadian rhythm and sleep state in patients with acute cerebral infarction (ACI) accompanied by sleep-breathing...
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The circadian rhythm gene Bmal1 ameliorates acute deoxynivalenol-induced liver damage
Deoxynivalenol (DON) is widely emerging in various grain crops, milk, and wine products, which can trigger different toxic effects on humans and...
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Ablation of microglia does not alter circadian rhythm of locomotor activity
Microglia, as macrophages in the brain, are responsible for immune responses and synaptic remodeling. Although the function of microglia is regulated...
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Assaying Circadian Locomotor Activity Rhythm in Drosophila
Drosophila melanogaster has been an instrumental animal model for defining key properties of circadian rhythms and for investigating the cellular and...
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Prophylactic Treatment of ASD Based on Sleep-Wake Circadian Rhythm Formation in Infancy to Early Childhood
The pathogenesis underlying autism spectrum disorder (ASD) and the causes of rapid increase of ASD patients remain unclear. However, recent reports...