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Effective bowel management in spinal cord injury during inpatient rehabilitation: data from the Dutch spinal cord injury database
Study DesignRetrospective Observational Study.
ObjectivesTo describe bowel management in individuals with a recently acquired spinal cord injury...
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Feasibility of home hand rehabilitation using musicglove after chronic spinal cord injury
Study designRandomized, controlled single-blind cross over study. This study was registered on ClinicalTrials.gov (NCT02473614).
Objectives ...
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The Effect of Glycine and N-Acetylcysteine on Oxidative Stress in the Spinal Cord and Skeletal Muscle After Spinal Cord Injury
Oxidative stress is a frequently occurring pathophysiological feature of spinal cord injury (SCI) and can result in secondary injury to the spinal...
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Spinal cord stimulation for neuropathic pain following traumatic spinal cord injury: a case report
IntroductionNeuropathic pain is a common complication of spinal cord injury (SCI), and is notoriously difficult to adequately treat. Gunshot wounds...
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Contrast enhanced ultrasound for traumatic spinal cord injury: an overview of current and future applications
Study designSystematic review.
ObjectiveContrast-enhanced ultrasound (CEUS) is an imaging modality that has only recently seen neurosurgical...
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Changes in bladder emptying during inpatient rehabilitation after spinal cord injury and predicting factors: data from the Dutch Spinal Cord Injury Database
Study designSecondary analysis of multicentre prospective observational data.
ObjectivesTo describe methods of bladder emptying at admission and...
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Unintentionally intentional: unintended effects of spinal stimulation as a platform for multi-modal neurorehabilitation after spinal cord injury
Electrical stimulation of spinal neurons has emerged as a valuable tool to enhance rehabilitation after spinal cord injury. In separate...
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Pathological hemodynamic changes and leukocyte transmigration disrupt the blood–spinal cord barrier after spinal cord injury
BackgroundBlood–spinal cord barrier (BSCB) disruption is a key event after spinal cord injury (SCI), which permits unfavorable blood-derived...
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Inhibition of UHRF1 Improves Motor Function in Mice with Spinal Cord Injury
Spinal-cord injury (SCI) is a severe condition that can lead to limb paralysis and motor dysfunction, and its pathogenesis is not fully understood....
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Single cell profiling of CD45+ spinal cord cells reveals microglial and B cell heterogeneity and crosstalk following spinal cord injury
BackgroundImmune cells play crucial roles after spinal cord injury (SCI). However, incomplete knowledge of immune contributions to injury and repair...
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Perceptions of critically ill individuals with acute and chronic spinal cord injury requiring a tracheostomy tube
Study designObservational study.
ObjectivesTo evaluate the perceptions of patients requiring a tracheostomy tube and to identify possible different...
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Relationships between cardiovascular disease risk, neuropathic pain, mental health, and autonomic function in chronic spinal cord injury
Study designMulticentre, cross-sectional study.
ObjectivesTo determine if clinical measures of poor mental health (MH-) and neuropathic pain (NP)...
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Oxygen therapy attenuates neuroinflammation after spinal cord injury
Acute hyperbaric O 2 (HBO) therapy after spinal cord injury (SCI) can reduce inflammation and increase neuronal survival. To our knowledge, it is...
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Plastic Changes Induced by Motor Activity in Spinal Cord Injury
Plastic changes in the central nervous system occurring under the influence of motor activity are regarded as the key to the successful restoration...
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Natural and targeted circuit reorganization after spinal cord injury
A spinal cord injury disrupts communication between the brain and the circuits in the spinal cord that regulate neurological functions. The...
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Promoting community engagement in spinal cord injury research: a case example
Community engagement is an important method of knowledge translation in spinal cord injury (SCI) research where researchers collaborate with people...
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Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain
BackgroundMedical advances have made it increasingly possible for spinal cord injury (SCI) survivors to survive decades after the insult. But how SCI...
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Unravelling the Road to Recovery: Mechanisms of Wnt Signalling in Spinal Cord Injury
Spinal cord injury (SCI) is a complex neurodegenerative pathology that consistently harbours a poor prognostic outcome. At present, there are few...
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Microglia/macrophages are ultrastructurally altered by their proximity to spinal cord injury in adult female mice
Traumatic spinal cord injury can cause immediate physical damage to the spinal cord and result in severe neurological deficits. The primary,...
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Exosomes Derived from Mesenchymal Stem Cells: Therapeutic Opportunities for Spinal Cord Injury
Spinal cord injury (SCI) is a serious neurological condition comprising primary and secondary injury and causing severe neurological impairments. The...