Search
Search Results
-
Clinical features, treatment, and outcome of pembrolizumab induced cholangitis
Pembrolizumab induced hepatitis has received increasing attention, while pembrolizumab induced cholangitis is poorly understood. This study...
-
Hematologic traits and primary biliary cholangitis: a Mendelian randomization study
Hematologic abnormalities was observationally associated with the susceptibility of primary biliary cholangitis (PBC). However, the conclusion is...
-
Clinical and microbiological characteristics of reflux cholangitis following bilio-enteric anastomosis
Twenty-five patients with reflux cholangitis (RC) defined as acute cholangitis (AC) with normal abdominal imaging occurring > 3 months after...
-
Network proximity analysis as a theoretical model for identifying potential novel therapies in primary sclerosing cholangitis
Primary Sclerosing Cholangitis (PSC) is a progressive cholestatic liver disease with no licensed therapies. Previous Genome Wide Association Studies...
-
Treatment with a JAK1/2 inhibitor ameliorates murine autoimmune cholangitis induced by IFN overexpression
The interferon (IFN) signaling pathways are major immunological checkpoints with clinical significance in the pathogenesis of autoimmunity. We have...
-
The Experience of Using Multipotent Mesenchymal Stromal Cells in the Treatment of Severe Recurrent Cholangitis in Children with Biliary Atresia after Kasai Surgery
This article describes the experience of application of multipotent mesenchymal stromal cells in the complex therapy of severe recurrent cholangitis...
-
Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD): a condition exemplifying the crosstalk of the gut–liver axis
The close relationship between primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) provides a good opportunity to comprehend...
-
An Assessment of the Serum Activity of ADH and ALDH in Patients with Primary Biliary Cholangitis
Primary biliary cholangitis (PBC; previously known as primary biliary cirrhosis) is a chronic inflammation-induced cholestatic process in the liver....
-
ANXA1 is identified as a key gene associated with high risk and T cell infiltration in primary sclerosing cholangitis
BackgroundPrimary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease, with unclear pathogenesis. Although immune disorders,...
-
Specificities of acute cholangitis in patients with cancer: a retrospective comparative study of 130 episodes
Pancreatic and biliary duct cancers are increasing causes of acute cholangitis (AC). We retrospectively characterize 81 cancer-associated cholangitis...
-
Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is an immune-mediated disease of the bile ducts that co-occurs with inflammatory bowel disease (IBD) in almost...
-
-
Fenofibrate Downregulates NF-κB Signaling to Inhibit Pro-inflammatory Cytokine Secretion in Human THP-1 Macrophages and During Primary Biliary Cholangitis
Chronic liver diseases, e.g., cholestasis, are negatively impacted by inflammation, which further aggravates liver injury. Pharmacotherapy targeting...
-
Multi-omics approaches for drug-response characterization in primary biliary cholangitis and autoimmune hepatitis variant syndrome
BackgroundPrimary biliary cholangitis (PBC) and autoimmune hepatitis (AIH) variant syndrome (VS) exhibit a complex overlap of AIH features with PBC,...
-
A case report and review of acute cholangitis with septic shock induced by Edwardsiella tarda
BackgroundEdwardsiella tarda ( E. tarda ) is a gram-negative facultative anaerobic bacterium. Gastroenteritis is the most common manifestation of E....
-
Microorganisms in Pathogenesis and Management of Primary Biliary Cholangitis (with Focus on Molecular Mimicry)
Primary biliary cholangitis (PBC) has been considered an enigmatic autoimmune liver disease. The immunopathogenesis of PBC has been considered a...
-
Microorganisms in the Pathogenesis and Management of Primary Biliary Cholangitis (with Focus on SARS-CoV-2 & Gut Microbiota)
Primary biliary cholangitis is a chronic cholestatic liver disease characterized by a selective and progressive destruction of interlobular bile...
-
Temocillin as an alternative treatment for acute bacterial cholangitis: a retrospective microbiology susceptibility-based study of 140 episodes
With rising antibiotic resistance, alternatives to carbapenems are needed for acute cholangitis (AC). Temocillin reaches high biliary concentrations...
-
Primary Biliary Cholangitis
Primary biliary cholangitis (PBC), formally named primary biliary cirrhosis until 2016, is a chronic cholestatic liver disease that can potentially...
-
Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a chronic, fibro-inflammatory disease of the intrahepatic and extrahepatic bile ducts and is strongly...