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Knowledge, Attitudes and Practices of Chagas a Neglected Tropical Disease in Rural Communities of the Colombian Caribbean, CHAGCOV Study
PurposeChagas disease (CD) a Neglected Tropical Diseases is an important public health issue in countries where is still endemic, included in the...
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Cytokine profile levels and their relationship with parasitemia and cardiomyopathy in people with Chagas disease in Spain. A prospective observational study
Immunoregulatory networks may have a role in controlling parasitemia in the chronic phase of human Chagas disease. The aim was to describe the serum...
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Chagas Disease and Leishmaniasis, Sympatric Zoonoses Present in Human from Rural Communities of Venezuela
PurposeTrypanosoma cruzi and Leishmania spp. coexist in several endemic areas, and there are few studies of Chagas disease and leishmaniasis...
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Chagas parasite classification in blood sample images using different machine learning architectures
Chagas disease is a life-threatening illness mainly found in Latin America. Early identification and diagnosis of Chagas disease are critical for...
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Immunization with a Trypanosoma cruzi cyclophilin-19 deletion mutant protects against acute Chagas disease in mice
Human infection with the protozoan parasite Trypanosoma cruzi causes Chagas disease for which there are no prophylactic vaccines. Cyclophilin 19 is a...
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Parasitological and molecular characterization of Trypanosoma cruzi of triatomines and mammals from endemic areas for Chagas disease in Venezuela
It is estimated that 6–7 million people worldwide are infected with Trypanosoma cruzi , the parasite that causes Chagas disease. In Venezuela, Chagas...
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Immunoglobulin and T cell receptor repertoire changes induced by a prototype vaccine against Chagas disease in naïve rhesus macaques
BackgroundA vaccine against Trypanosoma cruzi , the agent of Chagas disease, would be an excellent additional tool for disease control. A recombinant...
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Nifurtimox for Treatment of Chagas Disease in Pediatric Patients: the Challenges of Applying Pharmacokinetic-Pharmacodynamic Principles to Dose Finding
The antiparasitic drug nifurtimox was approved in the USA in 2020 for the treatment of patients with Chagas disease aged less than 18 years and...
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Fluralaner systemic treatment of chickens results in mortality in Triatoma gerstaeckeri, vector of the agent of Chagas disease
BackgroundChagas disease remains a persistent vector-borne neglected tropical disease throughout the Americas and threatens both human and animal...
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Chagas Disease
Chagas disease is a parasitic infection that has become an emerging public health concern in the United States. There are an estimated 300,000 people...
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Effective residual convolutional neural network for Chagas disease parasite segmentation
Considered a neglected tropical pathology, Chagas disease is responsible for thousands of deaths per year and it is caused by the parasite Trypanosoma...
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Newly Approved Anti-parasitic Drugs for Malaria, Fascioliasis, Onchocerciasis, Chagas Disease, and African Trypanosomiasis
The global burden of parasitic diseases combined is unknown, but hundreds of millions of the people are infected each year, with the greatest charge...
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Diagnostic Accuracy of Two Molecular Tools for Diagnosis of Congenital Chagas Disease
Background and ObjectiveThe real prevalence of congenital Chagas disease is undefined because of difficulties in the detection of Trypanosoma cruzi ...
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Assessing antibody decline after chemotherapy of early chronic Chagas disease patients
BackgroundChagas disease remains a significant public health problem in Latin America. There are only two chemotherapy drugs, nifurtimox and...
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Technological advances in the serological diagnosis of Chagas disease in dogs and cats: a systematic review
BackgroundChagas disease (CD) is caused by Trypanosoma cruzi , which is transmitted mainly through the feces/urine of infected triatomine bugs. The...
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Chagas Disease in Europe
Chagas disease caused by the protozoa Trypanosoma cruzi is a major emerging parasitic infection in Europe fueled by the increasing transnational...
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The Role of the Oxidative Stress-Inflammation Axis in the COVID-19-Infected Patients with Chagas Disease: A Key Parameter To Be Considered During the Pandemic
Purpose of ReviewThe global COVID-19 pandemic has become a major public health problem since December 2019, affecting millions of people, especially...
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TriatoScore: an entomological-risk score for Chagas disease vector control-surveillance
BackgroundTriatomine bugs transmit Chagas disease across Latin America, where vector control-surveillance is increasingly decentralized. Locally run...
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IgG Subclass Analysis in Patients with Chagas Disease 4 Years After Benznidazole Treatment
BackgroundIn humans, Trypanosoma cruzi infection is controlled by a complex immune response. Immunoglobulin G (IgG) is important for opsonizing...
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Does Trypanosoma cruzi (Chagas, 1909) (Kinetoplastida: Trypanosomatidae) modify the antennal phenotype of Triatoma dimidiata (Latreille, 1811) (Hemiptera: Triatominae)?
BackgroundTriatoma dimidiata is a vector of the protozoan parasite Trypanosoma cruzi , the etiologic agent of Chagas disease. Phenotypic plasticity...
