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Central Pattern Generators
Central pattern generators (CPGs) are circuits of neurons – coupled by chemical synapses and often gap junctions (Marder et al., Dev Neurobiol... -
Central pattern generator network model for the alternating hind limb gait of rats based on the modified Van der Pol equation
Herein, we employed a central pattern generator (CPG), a spinal cord neural network that regulates lower-limb gait during intra-spinal...
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Motoneuronal Regulation of Central Pattern Generator and Network Function
This chapter reviews recent work showing that vertebrate motoneurons can trigger spontaneous rhythmic activity in the develo** spinal cord and can... -
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Computational modeling predicts regulation of central pattern generator oscillations by size and density of the underlying heterogenous network
Central pattern generators are characterized by a heterogeneous cellular composition, with different cell types playing distinct roles in the...
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A new biological central pattern generator model and its relationship with the motor units
The central pattern generator (CPG) is a key neural-circuit component of the locomotion control system. Recently, numerous molecular and genetic...
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What Can Bidirectional Walking Tell Us about Central Pattern Generators?
We report here an experimental-theoretical study of the features of the EMG activity of the iliopsoas (IP), tibialis anterior (TA), and gastrocnemius...
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Intersegmental coordination of the central pattern generator via interleaved electrical and chemical synapses in zebrafish spinal cord
A significant component of the repetitive dynamics during locomotion in vertebrates is generated within the spinal cord. The legged locomotion of...
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COVID-19 and silent hypoxemia in a minimal closed-loop model of the respiratory rhythm generator
Silent hypoxemia, or “happy hypoxia,” is a puzzling phenomenon in which patients who have contracted COVID-19 exhibit very low oxygen saturation (
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Temporal variations in the pattern of breathing: techniques, sources, and applications to translational sciences
The breathing process possesses a complex variability caused in part by the respiratory central pattern generator in the brainstem; however, it also...
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Black-white hole pattern: an investigation on the automated chronic neuropathic pain detection using EEG signals
Electroencephalography (EEG) signals provide information about the brain activities, this study bridges neuroscience and machine learning by...
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Central Sleep Apnea in Patients with Neurological Disorders
PurposeThe prevalence and pathophysiology of central sleep apnea (CSA) in neurology patients seem to vary greatly and have yet to be well...
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Lattice 123 pattern for automated Alzheimer’s detection using EEG signal
This paper presents an innovative feature engineering framework based on lattice structures for the automated identification of Alzheimer's disease...
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Asymmetric Control of Coexisting Slow and Fast Rhythms in a Multifunctional Central Pattern Generator: A Model Study
Using a simulation approach, we propose a biophysically feasible mechanism describing how a multifunctional central pattern generator (CPG) can...
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Neural network model of an amphibian ventilatory central pattern generator
The neuronal multiunit model presented here is a formal model of the central pattern generator (CPG) of the amphibian ventilatory neural network,...
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The Bcm rule allows a spinal cord model to learn rhythmic movements
Currently, it is accepted that animal locomotion is controlled by a central pattern generator in the spinal cord. Experiments and models show that...
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