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Activation of the CXCR4 Receptor by Chemokine CXCL12 Increases the Excitability of Neurons in the Rat Central Amygdala
Primarily regarded as immune proteins, chemokines are emerging as a family of molecules serving neuromodulatory functions in the develo** and adult...
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Recruitment of hippocampal and thalamic pathways to the central amygdala in the control of feeding behavior under novelty
It is adaptive to restrict eating under uncertainty, such as during habituation to novel foods and unfamiliar environments. However, sustained...
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Dopaminergic innervation at the central nucleus of the amygdala reveals distinct topographically segregated regions
The central nucleus of the amygdala (CeA) is involved in the expression of fear and anxiety disorders. Anatomically, it is divided into medial (CeM),...
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Somatosensory cortex and central amygdala regulate neuropathic pain-mediated peripheral immune response via vagal projections to the spleen
Pain involves neuroimmune crosstalk, but the mechanisms of this remain unclear. Here we showed that the splenic T helper 2 (T H 2) immune cell response...
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Alteration of serotonin release response in the central nucleus of the amygdala to noxious and non-noxious mechanical stimulation in a neuropathic pain model rat
Previously, we found that serotonin (5-HT) release in the central nucleus of the amygdala (CeA) of anesthetized rats decreases in response to...
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Atrophy patterns in hippocampus and amygdala subregions of depressed patients with Parkinson's disease
We aimed to explore the subregional atrophy patterns of the amygdala and hippocampus in Parkinson's disease (PD) with depression and their...
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Smaller amygdala subnuclei volume in schizophrenia patients with violent behaviors
To investigate the association between the volume of amygdala subnuclei and violent behaviors in patients with schizophrenia (SCZ). In the present...
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The central nucleus of the amygdala and the construction of defensive modes across the threat-imminence continuum
In nature, animals display defensive behaviors that reflect the spatiotemporal distance of threats. Laboratory-based paradigms that elicit specific...
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Volume changes of hippocampal and amygdala subfields in patients with mild cognitive impairment and Alzheimer’s disease
BackgroundAutomated segmentation of hippocampal and amygdala subfields could improve classification accuracy of Mild Cognitive Impairments (MCI) and...
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Amygdala structure and function and its associations with social-emotional outcomes in a low-risk preterm sample
Amygdala atypical volume development and functional connectivity (FC) at small gestational ages (GA) have been found across childhood. This...
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Chronic kidney disease may evoke anxiety by altering CRH expression in the amygdala and tryptophan metabolism in rats
Chronic kidney disease (CKD) is associated with anxiety; however, its exact mechanism is not well understood. Therefore, the aim of the present study...
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Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning
The amygdala is a brain region primarily associated with emotional response. The use of genetic markers and single-cell transcriptomics can provide...
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A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety
Fear-related disorders (for example, phobias and anxiety) cause a substantial public health problem. To date, studies of the neural basis of fear...
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The Collicular–Pulvinar–Amygdala Axis and Adult-Onset Idiopathic Focal Dystonias
Adult-onset idiopathic focal dystonias (AOIFD) are the most common type of dystonia. It has varied expression including multiple motor (depending on...
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Classification of primary dysmenorrhea by brain effective connectivity of the amygdala: a machine learning study
BackgroundThe amygdala plays a crucial role in the central pathogenesis mechanism of primary dysmenorrhea (PDM). However, the detailed pain...
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Induction of Anxiety-Like Phenotypes by Knockdown of Cannabinoid Type-1 Receptors in the Amygdala of Marmosets
The amygdala is an important hub for regulating emotions and is involved in the pathophysiology of many mental diseases, such as depression and...
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Amygdala-Targeted Relief of Neuropathic Pain: Efficacy of Repetitive Transcranial Magnetic Stimulation in NLRP3 Pathway Suppression
This study investigates the effectiveness of repetitive transcranial magnetic stimulation (rTMS) as a nonpharmacological approach to treating...
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Interleukin-6 is correlated with amygdala volume and depression severity in adolescents and young adults with first-episode major depressive disorder
Inflammatory mechanisms may play crucial roles in the pathophysiology of major depressive disorder (MDD), and cytokine concentrations are correlated...