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The Role of Beta2-Microglobulin in Central Nervous System Disease
Central nervous system (CNS) disorders represent the leading cause of disability and the second leading cause of death worldwide, and impose a...
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The role of annexins in central nervous system development and disease
Annexins, a group of Ca 2+ -dependent phospholipid-binding proteins, exert diverse roles in neuronal development, normal central nervous system (CNS)...
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Central Nervous System Tumors
The central nervous system (CNS) is the part of the nervous system comprising the brain and the spinal cord. CNS tumors are a heterogeneous group of... -
Lymphomas of Central Nervous System
Central nervous systemCentral nervous system (CNS) (CNS) lymphoma consists of primary central nervous system lymphomaPrimary Central Nervous System... -
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Role of Peptidylarginine Deiminase 4 in Central Nervous System Diseases
The deimination or citrullination of arginine residues in the polypeptide chain by peptidylarginine deiminase 4 alters the charge state of the...
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Batokine in Central Nervous System Diseases
Brown adipose tissue (BAT) is a special type of fat tissue in mammals and is also a key endocrine organ in the human body. Batokine, the endocrine...
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Border-associated macrophages in the central nervous system
Tissue-resident macrophages play an important role in the local maintenance of homeostasis and immune surveillance. In the central nervous system...
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Secreted Glycoproteins That Regulate Synaptic Function: the Dispatchers in the Central Nervous System
Glycoproteins are proteins that contain oligosaccharide chains. As widely distributed functional proteins in the body, glycoproteins are essential...
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Physiological and pathological effects of phase separation in the central nervous system
Phase separation, also known as biomolecule condensate, participates in physiological processes such as transcriptional regulation, signal...
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The glymphatic system: implications for drugs for central nervous system diseases
In the past decade, evidence for a fluid clearance pathway in the central nervous system known as the glymphatic system has grown. According to the...
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Microglia regulation of central nervous system myelin health and regeneration
Microglia are resident macrophages of the central nervous system that have key functions in its development, homeostasis and response to damage and...
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MicroRNA‑124: an emerging therapeutic target in central nervous system disorders
The central nervous system (CNS) consists of neuron and non-neuron cells including neural stem/precursor cells (NSPCs), neuroblasts, glia cells...
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The Gut Microbiome and the Central Nervous System (CNS)
The presence of resident microbial species in the human gastrointestinal tract has been known for a long time. However, only recently have they been... -
Regulation of Glial Function by Noncoding RNA in Central Nervous System Disease
Non-coding RNAs (ncRNAs) are a class of functional RNAs that play critical roles in different diseases. NcRNAs include microRNAs, long ncRNAs, and...
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High Frequency of Autoantibodies in COVID-19 Patients with Central Nervous System Complications: a Multicenter Observational Study
We present a panel of central nervous system (CNS) complications associated with coronavirus disease 2019 (COVID-19) and their clinical...
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Localization Pattern of Dispatched Homolog 2 (DISP2) in the Central and Enteric Nervous System
Dispatched homolog (DISP) proteins have been implicated in the regulation of hedgehog signaling during embryologic development. Although DISP2 has...
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Immunotherapy for Primary Cancers of Central Nervous System
Primary CNS tumors, despite many advancements in the field of neurosurgery and radio-oncology, have remained universally lethal. Although, until a... -
Central nervous system anomalies in 41 Chinese children incontinentia pigmenti
IntroductionIncontinentia pigmenti (IP) is a rare neuroectodermal dysplasia caused by a defect in the IKBKG gene. The pathogenesis of central...
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Tripartite Motif Protein Family in Central Nervous System Diseases
Tripartite motif (TRIM) protein superfamily is a group of E3 ubiquitin ligases characterized by the conserved RING domain, the B-box domain, and the...