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Assessing the Elasticity of Child Cortical Bone
A better understanding of the mechanical behaviour of child bone is essential to improve the diagnosis of pediatric bone disorders that may influence...
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Vein wall thickness and severity of pulmonary involvement due to sars n-cov2 virus infection
BackgroundAn observational study involving patients recovered from COVID-19 was conducted in order to evaluate the presence/absence of vein wall...
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Gradient Biomaterials and Their Impact on Cell Migration
Cell migration participates in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel...
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Stem Cell Differentiation Mediated by Biomaterials/Surfaces
Directing the differentiation of stem cells into a specific stromal lineage such as adipocyte, chondrocyte, fibroblast, myocyte, and osteoblast cell...
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Biology, Chemistry, and Physics of Cancer Cell Motility and Metastasis
A malignant tumor has ability to invade the nearby tissues and colonize distant sites (organs) through the lymphatic/vascular system. From...
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Physiologically relevant platform for an advanced in vitro model of the vascular wall: focus on in situ fabrication and mechanical maturation
The mechanical stimulation applied on engineered vascular constructs in perfusion bioreactors has been shown to be beneficial for their maturation....
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Human umbilical cord mesenchymal stem cells reconstruct the vaginal wall of ovariectomized Sprague–Dawley rats: implications for pelvic floor reconstruction
Vaginal structural defects are involved in pelvic organ prolapse (POP). We tested whether mesenchymal stem cell (MSC) therapy can repair the...
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Transcription factors: key regulatory targets of vascular smooth muscle cell in atherosclerosis
Atherosclerosis (AS), leading to gradual occlusion of the arterial lumen, refers to the accumulation of lipids and inflammatory debris in the...
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Increased vascular smooth muscle cell senescence in aneurysmal Fibulin-4 mutant mice
Aortic aneurysms are dilatations of the aorta that can rupture when left untreated. We used the aneurysmal Fibulin-4 R/R mouse model to further...
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Scaffold-based 3D cell culture models in cancer research
Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional...
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Fluoride impairs vascular smooth muscle A7R5 cell lines via disrupting amino acids metabolism
Given the insidious and high-fatality nature of cardiovascular diseases (CVDs), the emergence of fluoride as a newly identified risk factor demands...
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Cuproptosis and copper deficiency in ischemic vascular injury and repair
Ischemic vascular diseases are on the rise globally, including ischemic heart diseases, ischemic cerebrovascular diseases, and ischemic peripheral...
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Establishment of a Biaxial Testing System for Characterization of Right Ventricle Viscoelasticity Under Physiological Loadings
PurposePrior studies have indicated an impact of cardiac muscle viscoelasticity on systolic and diastolic functions. However, the studies of...
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Phosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis
Abdominal aortic aneurysm (AAA) is a permanent expansion of the abdominal aorta that has a high mortality but limited treatment options....
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Intracerebral Administration of a Novel Self-Assembling Peptide Hydrogel Is Safe and Supports Cell Proliferation in Experimental Intracerebral Haemorrhage
Intracerebral haemorrhage (ICH) is the deadliest form of stroke, but current treatment options are limited, meaning ICH survivors are often left with...
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Pathogenic mechanisms and therapeutic implications of extracellular matrix remodelling in cerebral vasospasm
Cerebral vasospasm significantly contributes to poor prognosis and mortality in patients with aneurysmal subarachnoid hemorrhage. Current research...
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Exploring the Microcosm at Atomic Precision Using Atomic Force Microscopy
Atomic force microscopy (AFM) unlike electron microscopy and X-ray crystallography is one of the most sought-after mechanobiological approach to...
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Biosensors’ Utility in Mammalian Cell Culturing
Over the past three decades, sensors have swiftly emerged as the fundamental requirement for ascertaining the progress of molecular events....
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Caffeine activates HOG-signalling and inhibits pseudohyphal growth in Saccharomyces cerevisiae
ObjectiveCaffeine has a wide range of effects in humans and other organisms. Caffeine activates p38 MAPK, the human homolog to the Hog1 protein that...
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Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor
Propofol is widely used in clinical anesthesia due to its advantages of rapid onset and less adverse reactions. This study focused on the role of...
