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Mechanical Ablation of Larval Zebrafish Spinal Cord
Unlike mammals, adult and larval zebrafish exhibit robust regeneration following traumatic spinal cord injury. This remarkable regenerative capacity,...
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Spinal Cord Injury in African Killifish
Mammals are usually disabled after spinal cord injury (SCI) due to insufficient neuron regeneration. In contrast, many teleost fishes, like...
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Spinal Cord Neurogenesis
Neurogenesis is the term used to describe the generation of neurons in the central nervous system (CNS), a process that takes place largely during...
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Spinal Cord Neurogenesis
Neurogenesis is the term used to describe the generation of neurons in the central nervous system (CNS), a process that takes place largely during...
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Development and Developmental Disorders of the Spinal Cord
Even after its development is complete, the spinal cord remains a rather simple structure with a ventral motor horn, a dorsal sensory horn and an...
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Single-cell transcriptomic landscape of the develo** human spinal cord
Understanding spinal cord assembly is essential to elucidate how motor behavior is controlled and how disorders arise. The human spinal cord is...
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A Reproducible Spinal Cord Crush Injury in the Regeneration-Permissive Axolotl
Following injury, axolotls are able to functionally regenerate their spinal cord, regaining both motor and sensory control. In contrast, humans...
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Contrast enhanced ultrasound for traumatic spinal cord injury: an overview of current and future applications
Study designSystematic review.
ObjectiveContrast-enhanced ultrasound (CEUS) is an imaging modality that has only recently seen neurosurgical...
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Oxygen therapy attenuates neuroinflammation after spinal cord injury
Acute hyperbaric O 2 (HBO) therapy after spinal cord injury (SCI) can reduce inflammation and increase neuronal survival. To our knowledge, it is...
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Plastic Changes Induced by Motor Activity in Spinal Cord Injury
Plastic changes in the central nervous system occurring under the influence of motor activity are regarded as the key to the successful restoration...
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Human induced neural stem cells support functional recovery in spinal cord injury models
Spinal cord injury (SCI) is a clinical condition that leads to permanent and/or progressive disabilities of sensory, motor, and autonomic functions....
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Stereological Evaluation of Tissue Preservation After Neuroprotective Treatments for Traumatic Spinal Cord Injury
Spinal cord injury (SCI) is a major cause of permanent disability, and its causes and pathophysiological effects are very variable between patients....
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Transneuronal Delivery of Cytokines to Stimulate Mammalian Spinal Cord Regeneration
The spinal cord contains multiple fiber tracts necessary for locomotion. However, as a part of the central nervous system, they are extremely limited...
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Translating Colonic Sensory Afferent Peripheral Mechanosensitivity into the Spinal Cord Dorsal Horn
Sensory afferent signalling from the colon and rectum is relayed into the spinal cord. The spinal cord contains distinct neurocircuits that control...
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MST2 Acts via AKT Activity to Promote Neurite Outgrowth and Functional Recovery after Spinal Cord Injury in Mice
Spinal cord injury (SCI) constitutes a significant clinical challenge, and there is extensive research focused on identifying molecular activities...
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Spinal Cord Injury in the Mouse Using the Infinite Horizon Spinal Cord Impactor
Death of central nervous system neurons is a critical feature of spinal cord injury (SCI). The Infinite Horizon spinal cord impactor can be used to...
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Osteopontin enhances the effect of treadmill training and promotes functional recovery after spinal cord injury
In this study, we examined the combined impact of osteopontin (OPN) and treadmill training on mice with spinal cord injury (SCI). OPN was...
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Transplantation of olfactory mucosa mesenchymal stromal cells repairs spinal cord injury by inducing microglial polarization
Study designAnimal studies
ObjectivesTo evaluate the therapeutic effect of olfactory mucosa mesenchymal stem cell (OM-MSCs) transplantation in mice...
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Profiling spatiotemporal gene expression of the develo** human spinal cord and implications for ependymoma origin
The spatiotemporal regulation of cell fate specification in the human develo** spinal cord remains largely unknown. In this study, by performing...
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Epidural stimulation of the cervical spinal cord for post-stroke upper-limb paresis
Cerebral strokes can disrupt descending commands from motor cortical areas to the spinal cord, which can result in permanent motor deficits of the...
