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Deep learning imaging phenotype can classify metabolic syndrome and is predictive of cardiometabolic disorders
BackgroundCardiometabolic disorders pose significant health risks globally. Metabolic syndrome, characterized by a cluster of potentially reversible...
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Lymphocyte to High-density Lipoprotein Cholesterol Ratio is Positively Associated with Pre-diabetes, Metabolic Syndrome, and Non-traditional Cardiometabolic Risk Markers: A Cross-sectional Study at Secondary Health Care
High scores of lymphocyte-to-high-density lipoprotein cholesterol ratio (lymphocyte-to-HDL-c) may be a new indicator of inflammation and metabolic...
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Different effects of cardiometabolic syndrome on brain age in relation to gender and ethnicity
BackgroundA growing body of evidence shows differences in the prevalence of cardiometabolic syndrome (CMS) and dementia based on gender and...
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Does cardiometabolic risk profile differ among individuals with traumatic and non-traumatic spinal cord injury (SCI): the evidence from the multicenter SCI cohort in Switzerland (SwiSCI)
Study designLongitudinal study.
ObjectiveTo explore whether individuals with traumatic spinal cord injury (TSCI) and non-traumatic SCI (NTSCI)...
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Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes
BackgroundThis work is aimed at improving the understanding of cardiometabolic syndrome pathophysiology and its relationship with thrombosis by...
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Beyond BMI: cardiometabolic measures as predictors of impulsivity and white matter changes in adolescents
Obesity is characterized by cardiometabolic and neurocognitive changes. However, how these two factors relate to each other in this population is...
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Gut microbiome and cardiometabolic comorbidities in people living with HIV
BackgroundDespite modern antiretroviral therapy (ART), people living with HIV (PLWH) have increased relative risk of inflammatory-driven...
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Plasma water T2 detects age-stratified differences in cardiometabolic health among familial CCM patients with Hispanic CCM1 mutation
Cerebral cavernous malformations (CCMs) are abnormal clusters of capillaries in the nervous system. This pilot study analyzed the cardiometabolic...
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Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial
Large variability exists in people’s responses to foods. However, the efficacy of personalized dietary advice for health remains understudied. We...
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Targeting Retinol-Binding Protein 4 (RBP4) in the Management of Cardiometabolic Diseases
The ancient use of herbs for the treatment of various human diseases have been documented, with several scientific literatures supporting the use of...
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Circulating concentrations of free triiodothyronine are associated with central adiposity and cardiometabolic risk factors in young euthyroid adults
Thyroid dysfunction is associated with classic cardiometabolic risk factors in humans. However, this relationship remains unclear in young euthyroid...
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Effectiveness of high cardiorespiratory fitness in cardiometabolic protection in prediabetic rats
BackgroundCaloric restriction and exercise are lifestyle interventions that effectively attenuate cardiometabolic impairment. However,...
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Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease
BackgroundThe human gut harbors trillions of microbes that play dynamic roles in health. While the microbiome contributes to many cardiometabolic...
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Rowing exercise increases cardiorespiratory fitness and brachial artery diameter but not traditional cardiometabolic risk factors in spinal cord-injured humans
PurposeThis study assessed the effects of upper-body rowing exercise on cardiorespiratory fitness, traditional cardiometabolic risk factors, and...
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Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common endocrine–reproductive disorder affecting 8% to 13% of women of reproductive age worldwide. Although the... -
Gender differences in cardiometabolic health and disease in a cross-sectional observational obesity study
BackgroundBeyond the degree of adiposity, the pattern of fat distribution has a profound influence on cardiometabolic risk. It is unclear if sex...
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Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes
BackgroundIdentification of causal genes for polygenic human diseases has been extremely challenging, and our understanding of how physiological and...
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Sex and age differences in the association of fatty liver index-defined non-alcoholic fatty liver disease with cardiometabolic risk factors: a cross-sectional study
BackgroundDespite the extensive scientific evidence accumulating on the epidemiological risk factors for non-alcoholic fatty liver disease (NAFLD),...
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Patterns of change in obesity indices and other cardiometabolic risk factors before the diagnosis of type 2 diabetes: two decades follow-up of the Tehran lipid and glucose study
BackgroundIdentifying patterns of variation in obesity indices and other cardiometabolic risk factors before the diagnosis of type 2 diabetes could...