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Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer
Breast cancer is a malignant tumor that seriously endangers women’s lives. The prognosis of breast cancer patients differs among molecular types....
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Breast Cancer
Breast cancers are a major cause of mortality in females, on a par with lung and colon cancers. One topic in this chapter are the causes of breast... -
HERVK-mediated regulation of neighboring genes: implications for breast cancer prognosis
Human endogenous retroviruses (HERVs) are the remnants of ancient retroviral infections integrated into the human genome. Although most HERVs are...
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Expression of transglutaminase-2 (TGM2) in the prognosis of female invasive breast cancer
BackgroundTransglutaminase 2 (TGM2) is a protein expressed in several isoforms in both intra- and extra-cellular tissue compartments. It has multiple...
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Immunotherapy in Breast Cancer
Breast cancer affects 12% of women worldwide. Although advances in systemic, surgical, and radiation therapy approaches will cure a large proportion... -
Comment on “A novel super-enhancer-related gene signature predicts prognosis and immune microenvironment for breast cancer”
The primary aim of this study is to critically evaluate and comment on the research presented in the article titled “A Novel...
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Construction and validation of a hypoxia-related gene signature to predict the prognosis of breast cancer
BackgroundAmong the most common forms of cancer worldwide, breast cancer posed a serious threat to women. Recent research revealed a lack of oxygen,...
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Clinicopathological features and prognosis of patients with HER2-low breast cancer
BackgroundLow human epidermal growth factor receptor 2 (HER2) expression is an emerging concept in breast cancer that is defined as...
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Genetics and Epigenetics of Breast Cancer
This book discusses the contribution of genetics and epigenetics alterations in the initiation, development, and recurrence of breast cancer. It also...
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Impact of NDUFAF6 on breast cancer prognosis: linking mitochondrial regulation to immune response and PD-L1 expression
BackgroundBreast cancer is a major global health concern, and there is a continuous search for novel biomarkers to predict its prognosis. The...
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A novel super-enhancer-related gene signature predicts prognosis and immune microenvironment for breast cancer
BackgroundThis study targeted at develo** a robust, prognostic signature based on super-enhancer-related genes (SERGs) to reveal survival prognosis...
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CTCs in Early Breast Cancer
In the last decades, treatment options for breast cancer patients improved rapidly, leading to a more personalized treatment approach. At the moment,... -
Negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cells and patient prognosis after breast cancer surgery
ObjectiveTo investigate how the negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cell lines and prognosis in...
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Endogenous estrogen receptor modulating oxysterols and breast cancer prognosis: Results from the MARIE patient cohort
Background27-hydroxycholesterol (HC) and 25-HC were identified as endogenous selective estrogen receptor modulators (SERMs) and estrogen receptor...
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Biosimilars in Breast Cancer
Breast cancer is a significant health concern globally, leading to maximum mortalities amongst women worldwide, which is 11.6% of all cancers... -
A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer
Breast cancer is a heterogeneous disease with variable survival outcomes. Pathologists grade the microscopic appearance of breast tissue using the...
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Technological Advancements in Cancer Diagnosis and Prognosis
Cancer diagnostics and prognosis, propelled by cutting-edge technologies, navigates the evolution from traditional methods to innovative approaches... -
Technological Advancements in Cancer Diagnosis and Prognosis
Cancer diagnostics and prognosis, propelled by cutting-edge technologies, navigates the evolution from traditional methods to innovative approaches... -
Potential interplay between tumor size and vitamin D receptor (VDR) polymorphisms in breast cancer prognosis: a prospective cohort study
PurposeVitamin D has some anticancer properties that may decrease breast cancer risk and improve prognosis. The aim was to investigate associations...
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PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants
We assessed the PREDICT v 2.2 for prognosis of breast cancer patients with pathogenic germline BRCA1 and BRCA2 variants, using follow-up data from...