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Immunotherapy in Breast Cancer
Breast cancer affects 12% of women worldwide. Although advances in systemic, surgical, and radiation therapy approaches will cure a large proportion...
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Breast Cancer
Breast cancer is currently the most diagnosed cancer in the female population, with a prevalence of 1 in 8 women.
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Biosimilars in Breast Cancer
Breast cancer is a significant health concern globally, leading to maximum mortalities amongst women worldwide, which is 11.6% of all cancers...
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Breast Cancer
Breast cancers are a major cause of mortality in females, on a par with lung and colon cancers. One topic in this chapter are the causes of breast...
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Resistance to Immunotherapy in Breast Cancer
Breast cancer is the most common and second most deadly disease in women worldwide, with breast cancer screening resulting in a steady decline in...
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Resistance to Endocrine Therapy in Breast Cancer
The foremost cause of female deaths is due to breast cancer. The most frequent type of breast cancer is hormone-dependent breast cancer, being either...
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Immunotherapy for Breast Cancer
Breast cancer is one of the leading causes of mortality among women worldwide. Approximately 95% of breast malignancies are adenocarcinomas....
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Resistance to Targeted Therapy in Breast Cancer
The discoveries of breast cancer molecular subtypes and their deregulated pathways have given rise to the emergence of potential therapeutic targets...
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Mechanisms of Drug Resistance in Breast Cancer
The incidence of breast cancer has increased over the past decades making it the most common cancer in females worldwide. Multidrug resistance (MDR)...
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Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features
BackgroundThe tumor microenvironment clearly influences cancer progressing properties but less is known about how individual cancer microenvironments...
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CTCs in Early Breast Cancer
In the last decades, treatment options for breast cancer patients improved rapidly, leading to a more personalized treatment approach. At the moment,...
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Breast cancer patient-derived organoids for the investigation of patient-specific tumour evolution
BackgroundA reliable preclinical model of patient-derived organoids (PDOs) was developed in a case study of a 69-year-old woman diagnosed with breast...
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Negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cells and patient prognosis after breast cancer surgery
ObjectiveTo investigate how the negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cell lines and prognosis in...
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Role of Endorphins in Breast Cancer Pathogenesis and Recovery
Understanding the relationship between stress and breast cancer development is essential to preventing and alleviating the cancer. Recent research...
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Animal Models in Cancer Research: Breast Cancer
This chapter covers the main animal models employed in basic research to study breast cancer, including murine (chemically induced, transplanted,...
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Factors associated with engraftment success of patient-derived xenografts of breast cancer
BackgroundPatient-derived xenograft (PDX) models serve as a valuable tool for the preclinical evaluation of novel therapies. They closely replicate...
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Breast Cancer Therapy and Control
We discuss breast cancer therapy using drugs in this chapter. Genetic mutations are usually irreversible and they cannot be altered by giving drugs...
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Obesity and breast cancer prognosis: pre-diagnostic anthropometric measures in relation to patient, tumor, and treatment characteristics
PurposeExamine the association between obesity and clinical outcomes in early breast cancer and assess if patient, tumor, and treatment...
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Genomic Landscape of Breast Cancer
Understanding the genomic landscape of breast cancer is a very active and rapidly evolving research area. Genome wide searches have been conducted by...
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Molecular Profiling and Personalized Medicine in Drug-Resistant Breast Cancer
The utilization of molecular profiling techniques and personalized medicine approaches in the management of breast cancer is driven by molecular...