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Body mass index, triglyceride-glucose index, and prostate cancer death: a mediation analysis in eight European cohorts
BackgroundInsulin resistance is a hypothesised biological mechanism linking obesity with prostate cancer (PCa) death. Data in support of this...
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The impact of body mass index and physical disability on home-based anal self-sampling
PurposeSelf-sampling is increasingly being used in screening programs, yet no studies to date have examined the impact of bodily characteristics on...
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Variability of polygenic prediction for body mass index in Africa
BackgroundPolygenic prediction studies in continental Africans are scarce. Africa’s genetic and environmental diversity pose a challenge that limits...
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Trajectories of body mass index in adulthood and risk of subtypes of postmenopausal breast cancer
BackgroundBody fatness is a dynamic exposure throughout life. To provide more insight into the association between body mass index (BMI) and...
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Differential effects of cholesterol levels on cognition according to body mass index in Parkinson’s disease
BackgroundCholesterol is an essential component of the neuronal cell membrane and is crucial for neuronal function; however, the role of cholesterol...
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Body Mass as a Biomarker and Femoral Fracture
Body mass represents a wide range of components, from atoms to tissues or organs. In clinical practice, body composition is generally assessed at the...
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COVID-19, Anxiety, and Body Mass Index Increase Leptin Levels: a Cross-sectional Multicentric Study
Although many efforts have been made to understand the pathophysiological mechanisms of COVID-19, critical gaps remain to be explored. This study...
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Combined associations of a healthy lifestyle and body mass index with colorectal cancer recurrence and survival: a cohort study
PurposeColorectal cancer (CRC) risk is associated with modifiable lifestyle factors including smoking, physical inactivity, Western diet, and excess...
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Reporting on patient’s body mass index (BMI) in recent clinical trials for patients with breast cancer: a systematic review
BackgroundThe proportion of patients with breast cancer and obesity is increasing. While the therapeutic landscape of breast cancer has been...
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Associations between sex, body mass index and the individual microglial response in Alzheimer’s disease
Background and objectives18-kDa translocator protein position-emission-tomography (TSPO-PET) imaging emerged for in vivo assessment of...
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FTO and MC4R polymorphisms, and selected pre-, peri- and postnatal factors as determinants of body mass index and fatness in children: a thorough analysis of the associations
BackgroundOverweight and obesity among children have become significant global health concerns. Previous studies have highlighted the potential role...
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Body mass index stratification optimizes polygenic prediction of type 2 diabetes in cross-biobank analyses
Type 2 diabetes (T2D) shows heterogeneous body mass index (BMI) sensitivity. Here, we performed stratification based on BMI to optimize predictions...
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Multiomic signatures of body mass index identify heterogeneous health phenotypes and responses to a lifestyle intervention
Multiomic profiling can reveal population heterogeneity for both health and disease states. Obesity drives a myriad of metabolic perturbations and is...
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Alcohol consumption and cancer incidence in women: interaction with smoking, body mass index and menopausal hormone therapy
BackgroundAlcohol consumption has been associated with increased risks of certain site-specific cancers and decreased risks of some other cancers....
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Body mass index and two-year change of in vivo Alzheimer’s disease pathologies in cognitively normal older adults
BackgroundLow body mass index (BMI) or underweight status in late life is associated with an increased risk of dementia or Alzheimer’s disease (AD)....
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Long-term effects of aromatase inhibitors on body mass index among postmenopausal breast cancer survivors in Africa: observational cohort study
Purposethis study was conducted to assess the impact of AIs on body mass index and high sensitivity as prognostic predictors to be incorporated into...
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A microbial causal mediation analytic tool for health disparity and applications in body mass index
BackgroundEmerging evidence suggests the potential mediating role of microbiome in health disparities. However, no analytic framework can be directly...
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Body mass index–based predictions and personalized clinical strategies for colorectal cancer in the context of PPPM
Currently colorectal cancer (CRC) is the third most prevalent cancer worldwide. Body mass index (BMI) is frequently used in CRC screening and risk...
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Body mass index and additional risk factors for cancer in adults with cystic fibrosis
BackgroundAdults with cystic fibrosis (CF) have an increased risk of a variety of cancers, notably gastrointestinal cancers. In CF higher body mass...
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Disentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation
BackgroundBody mass index (BMI) is known to influence the risk of various site-specific cancers, however, dissecting which subcomponents of this...
