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Immunomodulatory contribution of mast cells to the regenerative biomaterial microenvironment
Bioactive immunomodulatory biomaterials have shown promise for influencing the immune response to promote tissue repair and regeneration. Macrophages...
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The importance of 3D fibre architecture in cancer and implications for biomaterial model design
The need for improved prediction of clinical response is driving the development of cancer models with enhanced physiological relevance. A new...
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In silico Mechanics of Stem Cells Intramyocardially Transplanted with a Biomaterial Injectate for Treatment of Myocardial Infarction
PurposeBiomaterial and stem cell delivery are promising approaches to treating myocardial infarction. However, the mechanical and biochemical...
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An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells
In situ tissue regeneration utilizes the regenerative potential of the body to control cell behaviors for tissue repair. The design of scaffolding...
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Interfaces to Control Cell-Biomaterial Adhesive Interactions
Cell adhesion to adsorbed proteins and adhesive sequences engineered on surfaces is crucial to cellular and host responses to implanted devices,...
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Control of the post-infarct immune microenvironment through biotherapeutic and biomaterial-based approaches
Ischemic heart failure (IHF) is a leading cause of morbidity and mortality worldwide, for which heart transplantation remains the only definitive...
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Self-Assembling Nanopeptides Become a New Type of Biomaterial
Combining physics, engineering, chemistry and biology, we can now design, synthesize and fabricate biological nano-materials at the molecular...
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Effectiveness of biomaterial-based combination strategies for spinal cord repair – a systematic review and meta-analysis of preclinical literature
Study designSystematic review and meta-analysis of preclinical literature.
ObjectivesTo assess the effects of biomaterial-based combination (BMC)...
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Analysing the effects of metallic biomaterial design and imaging sequences on MRI interpretation challenges due to image artefacts
Biometals cause signal loss and susceptibility artefacts in the surrounding tissue, resulting in deterioration in magnetic resonance (MR) images....
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Application of silk fibroin coatings for biomaterial surface modification: a silk road for biomedicine
Silk fibroin (SF) as a natural biopolymer has become a popular material for biomedical applications due to its minimal immunogenicity, tunable...
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Biomaterial-based immunotherapeutic strategies for rheumatoid arthritis
Rheumatoid arthritis (RA) is an extremely painful autoimmune disease characterized by chronic joint inflammation leading to the erosion of adjacent...
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Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues
Decellularized extracellular matrix in the form of patches and locally injected hydrogels has long been used as therapies in animal models of...
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Efficacy and safety of autologous or allogeneic mesenchymal stromal cells from adult adipose tissue expanded and combined with tricalcium phosphate biomaterial for the surgical treatment of atrophic nonunion of long bones: a phase II clinical trial
BackgroundAutologous bone grafting is the standard treatment for the surgical management of atrophic nonunion of long bones. Other solutions, such as...
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An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial
Soft tissue reconstruction remains an intractable clinical challenge as current surgical options and synthetic implants may produce inadequate...
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New Insights into the Applications of 3D-Printed Biomaterial in Wound Healing and Prosthesis
Recently three-dimensional bioprinting (3D-bioP) has emerged as a revolutionary technique for numerous biomedical applications. 3D-bioP has...
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“Platelet-Rich Fibrin Membrane-as a novel biomaterial for pressure injury healing in a person with spinal cord injury: A case report”
IntroductionPressure injury (PI) impacts the quality of life, and socioeconomic and psychological well-being negatively in persons with Spinal Cord...
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Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock
Most bacterial vaccines work for a subset of bacterial strains or require the modification of the antigen or isolation of the pathogen before vaccine...
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Platelet-derived biomaterial with hyaluronic acid alleviates temporal-mandibular joint osteoarthritis: clinical trial from dish to human
BackgroundBioactive materials have now raised considerable attention for the treatment of osteoarthritis (OA), such as knee OA, rheumatoid OA, and...
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Fouling in ocular devices: implications for drug delivery, bioactive surface immobilization, and biomaterial design
The last 30 years has seen a proliferation of research on protein-resistant biomaterials targeted at designing bio-inert surfaces, which are...
