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Pretreatment prostate-specific antigen density as a predictor of biochemical recurrence in patients with prostate cancer: a meta-analysis
BackgroundA consensus has not been reached on the value of prostate-specific antigen density (PSAD) as a predictor of biochemical recurrence of...
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Biopsy-free AI-aided precision MRI assessment in prediction of prostate cancer biochemical recurrence
BackgroundTo investigate the predictive ability of high-throughput MRI with deep survival networks for biochemical recurrence (BCR) of prostate...
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Biochemical recurrence in patients with prostate cancer after primary definitive therapy: treatment based on risk stratification
BackgroundNearly one-third of patients with prostate cancer (PCa) experience biochemical recurrence (BCR) after primary definitive treatment. BCR...
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N6-methyladenosine modified lncRNAs signature for stratification of biochemical recurrence in prostate cancer
Nonmutational epigenetic reprogramming is a crucial mechanism contributing to the pronounced heterogeneity of prostate cancer (PCa). Among these...
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Model risk scores may underestimate rate of biochemical recurrence in African American men with localized prostate cancer: a cohort analysis of over 3000 men
IntroductionThis study aims to determine if there is a difference in prostate cancer nomogram-adjusted risk of biochemical recurrence (BCR) and/or...
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The impact of PSMA PET on the treatment and outcomes of men with biochemical recurrence of prostate cancer: a systematic review and meta-analysis
BackgroundProstate-specific membrane antigen (PSMA) PET is highly sensitive in identifying disease recurrence in men with biochemical recurrence of...
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Early biochemical outcomes following PSMA guided approach for bIoCHEmical relapse after prostatectomy-PSICHE trial (NCT05022914): preliminary results
PSICHE (NCT05022914) is a prospective trial to test a [ 68 Ga]Ga- PSMA-11 PET/CT imaging tailored strategy. All evaluable patients had biochemical...
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Obesity and biochemical recurrence in clinically localised prostate cancer: a systematic review and meta-analysis of 86,490 patients
BackgroundThe association of obesity with biochemical recurrence (BCR) after treatment of clinically localised prostate cancer (PC) shows...
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Head-to-head comparison of 68Ga-PSMA-11 PET/CT and 68Ga-PSMA-11 PET/MRI in the detection of biochemical recurrence of prostate cancer: summary of head-to-head comparison studies
PurposeOur meta-analysis aimed to evaluate the diagnostic performance of 68 Ga-PSMA-11 PET/CT vs. 68 Ga-PSMA-11 PET/MRI for biochemical recurrence of...
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Metabolic syndrome and its components predict the biochemical recurrence and adverse pathological features of patients following radical prostatectomy: a propensity score matching study
BackgroundTo investigate the predictive value of metabolic syndrome (MetS) and its components in biochemical recurrence (BCR) and adverse...
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Predicting biochemical-recurrence-free survival using a three-metabolic-gene risk score model in prostate cancer patients
BackgroundBiochemical recurrence (BCR) after initial treatment, such as radical prostatectomy, is the most frequently adopted prognostic factor for...
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Antidepressant medication use and prostate cancer recurrence in men with depressive disorders
PurposeWhether treating prostate cancer survivors with a depressive disorder with antidepressants can affect their cancer outcomes is unknown. We...
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Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution
Intratumor heterogeneity underlies cancer evolution and treatment resistance, but targetable mechanisms driving intratumor heterogeneity are poorly...
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Direct comparison of low-dose-rate brachytherapy versus radical prostatectomy using the surgical definition of biochemical recurrence for patients with intermediate-risk prostate cancer
BackgroundWe compared the oncological outcomes of patients who received seed brachytherapy (SEED-BT) with those who received radical prostatectomy...
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Independent validation of a pre-specified four-kallikrein marker model for prediction of adverse pathology and biochemical recurrence
BackgroundAccurate markers for prostate cancer (PC) risk stratification could aid decision-making for initial management strategies. The 4Kscore has...
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Preoperative PSMA-PET/CT as a predictor of biochemical persistence and early recurrence following radical prostatectomy with lymph node dissection
BackgroundThis study aims to evaluate the predictive value of lymph nodes (LN) suspicious for metastases on preoperative prostate-specific membrane...
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Biomarkers in Tumor Recurrence and Metastasis
Biomolecules that are produced or secreted by tumor cells themselves or in response to tumor by other cells of body are cancer biomarkers that... -
The ferroptosis-related long non-coding RNAs signature predicts biochemical recurrence and immune cell infiltration in prostate cancer
BackgroundFindings from numerous studies have revealed that ferroptosis is closely related to tumorigenesis and immune cell infiltration. Long...