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  1. Pretreatment prostate-specific antigen density as a predictor of biochemical recurrence in patients with prostate cancer: a meta-analysis

    Background

    A consensus has not been reached on the value of prostate-specific antigen density (PSAD) as a predictor of biochemical recurrence of...

    Feilun Cui, Yue Qiu, ... Yu Fan in BMC Cancer
    Article Open access 06 March 2024
  2. Biopsy-free AI-aided precision MRI assessment in prediction of prostate cancer biochemical recurrence

    Background

    To investigate the predictive ability of high-throughput MRI with deep survival networks for biochemical recurrence (BCR) of prostate...

    Ying Hou, Ke-Wen Jiang, ... Yu-Dong Zhang in British Journal of Cancer
    Article 27 September 2023
  3. Biochemical recurrence in patients with prostate cancer after primary definitive therapy: treatment based on risk stratification

    Background

    Nearly one-third of patients with prostate cancer (PCa) experience biochemical recurrence (BCR) after primary definitive treatment. BCR...

    Neal D. Shore, Judd W. Moul, ... Stephen J. Freedland in Prostate Cancer and Prostatic Diseases
    Article Open access 07 September 2023
  4. N6-methyladenosine modified lncRNAs signature for stratification of biochemical recurrence in prostate cancer

    Nonmutational epigenetic reprogramming is a crucial mechanism contributing to the pronounced heterogeneity of prostate cancer (PCa). Among these...

    Yingke Liang, Wenjun Yin, ... Jianming Lu in Human Genetics
    Article 27 September 2023
  5. Model risk scores may underestimate rate of biochemical recurrence in African American men with localized prostate cancer: a cohort analysis of over 3000 men

    Introduction

    This study aims to determine if there is a difference in prostate cancer nomogram-adjusted risk of biochemical recurrence (BCR) and/or...

    Matthew Epstein, Kaynaat Syed, ... Adam C. Reese in Prostate Cancer and Prostatic Diseases
    Article 11 October 2023
  6. The impact of PSMA PET on the treatment and outcomes of men with biochemical recurrence of prostate cancer: a systematic review and meta-analysis

    Background

    Prostate-specific membrane antigen (PSMA) PET is highly sensitive in identifying disease recurrence in men with biochemical recurrence of...

    Alex Pozdnyakov, Roshini Kulanthaivelu, ... Ur Metser in Prostate Cancer and Prostatic Diseases
    Article 19 April 2022
  7. Early biochemical outcomes following PSMA guided approach for bIoCHEmical relapse after prostatectomy-PSICHE trial (NCT05022914): preliminary results

    PSICHE (NCT05022914) is a prospective trial to test a [ 68 Ga]Ga- PSMA-11 PET/CT imaging tailored strategy. All evaluable patients had biochemical...

    Giulio Francolini, Michele Ganovelli, ... Lorenzo Livi in Clinical & Experimental Metastasis
    Article Open access 03 April 2023
  8. Obesity and biochemical recurrence in clinically localised prostate cancer: a systematic review and meta-analysis of 86,490 patients

    Background

    The association of obesity with biochemical recurrence (BCR) after treatment of clinically localised prostate cancer (PC) shows...

    Mario Rivera-Izquierdo, Javier Pérez de Rojas, ... José Juan Jiménez-Moleón in Prostate Cancer and Prostatic Diseases
    Article 06 January 2022
  9. Head-to-head comparison of 68Ga-PSMA-11 PET/CT and 68Ga-PSMA-11 PET/MRI in the detection of biochemical recurrence of prostate cancer: summary of head-to-head comparison studies

    Purpose

    Our meta-analysis aimed to evaluate the diagnostic performance of 68 Ga-PSMA-11 PET/CT vs. 68 Ga-PSMA-11 PET/MRI for biochemical recurrence of...

    Huasong Huo, Shurui Shen, ... Fuwei Yang in Prostate Cancer and Prostatic Diseases
    Article 05 August 2022
  10. Metabolic syndrome and its components predict the biochemical recurrence and adverse pathological features of patients following radical prostatectomy: a propensity score matching study

    Background

    To investigate the predictive value of metabolic syndrome (MetS) and its components in biochemical recurrence (BCR) and adverse...

    Zenan Liu, Xuehua Zhu, ... Jian Lu in BMC Cancer
    Article Open access 14 January 2023
  11. Predicting biochemical-recurrence-free survival using a three-metabolic-gene risk score model in prostate cancer patients

    Background

    Biochemical recurrence (BCR) after initial treatment, such as radical prostatectomy, is the most frequently adopted prognostic factor for...

    Yiqiao Zhao, Zijia Tao, ... **aonan Chen in BMC Cancer
    Article Open access 04 March 2022
  12. Antidepressant medication use and prostate cancer recurrence in men with depressive disorders

    Purpose

    Whether treating prostate cancer survivors with a depressive disorder with antidepressants can affect their cancer outcomes is unknown. We...

    Reina Haque, Stephanie Reading, ... Jeff Slezak in Cancer Causes & Control
    Article Open access 09 September 2022
  13. Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution

    Intratumor heterogeneity underlies cancer evolution and treatment resistance, but targetable mechanisms driving intratumor heterogeneity are poorly...

    Calixto-Hope G. Lucas, Kanish Mirchia, ... David R. Raleigh in Nature Genetics
    Article 17 May 2024
  14. Direct comparison of low-dose-rate brachytherapy versus radical prostatectomy using the surgical definition of biochemical recurrence for patients with intermediate-risk prostate cancer

    Background

    We compared the oncological outcomes of patients who received seed brachytherapy (SEED-BT) with those who received radical prostatectomy...

    Hideyasu Tsumura, Nobumichi Tanaka, ... Hiromichi Ishiyama in Radiation Oncology
    Article Open access 11 April 2022
  15. Independent validation of a pre-specified four-kallikrein marker model for prediction of adverse pathology and biochemical recurrence

    Background

    Accurate markers for prostate cancer (PC) risk stratification could aid decision-making for initial management strategies. The 4Kscore has...

    Martin Rasmussen, Jacob Fredsøe, ... Hans Lilja in British Journal of Cancer
    Article 13 December 2021
  16. Preoperative PSMA-PET/CT as a predictor of biochemical persistence and early recurrence following radical prostatectomy with lymph node dissection

    Background

    This study aims to evaluate the predictive value of lymph nodes (LN) suspicious for metastases on preoperative prostate-specific membrane...

    D. J. H. Baas, M. Schilham, ... D. M. Somford in Prostate Cancer and Prostatic Diseases
    Article 01 September 2021
  17. Biomarkers in Tumor Recurrence and Metastasis

    Biomolecules that are produced or secreted by tumor cells themselves or in response to tumor by other cells of body are cancer biomarkers that...
    Dilawar Khan, Mudassir Khan in Cancer Biomarkers in Diagnosis and Therapeutics
    Chapter 2022
  18. The ferroptosis-related long non-coding RNAs signature predicts biochemical recurrence and immune cell infiltration in prostate cancer

    Background

    Findings from numerous studies have revealed that ferroptosis is closely related to tumorigenesis and immune cell infiltration. Long...

    Chunhui Liu, Yue Gao, ... Ming Chen in BMC Cancer
    Article Open access 18 July 2022
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