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  1. Simple Behavioral Analysis (SimBA) as a platform for explainable machine learning in behavioral neuroscience

    The study of complex behaviors is often challenging when using manual annotation due to the absence of quantifiable behavioral definitions and the...

    Nastacia L. Goodwin, Jia J. Choong, ... Sam A. Golden in Nature Neuroscience
    Article 22 May 2024
  2. Pulsed Focused Ultrasound Reduces Hippocampal Volume Loss and Improves Behavioral Performance in the Kainic Acid Rat Model of Epilepsy

    Focused ultrasound (FUS) has the potential to modulate regional brain excitability and possibly aid seizure control; however, effects on behavior of...

    Po-Chun Chu, Chen-Syuan Huang, ... Hao-Li Liu in Neurotherapeutics
    Article Open access 14 March 2023
  3. Behavioral Tagging in the Develo** Animal

    Infancy is a critical period that shapes an individual’s emotional and developmental trajectory. Indeed, negative early life experiences have been...
    Sarah E. Bae, Rick Richardson in Synaptic Tagging and Capture
    Chapter 2024
  4. Administering a Behavioral Test Battery in Rodents

    Although animal models cannot broadly represent uniquely human psychiatric or psychological syndromes such as anxiety, depression, or schizophrenia,...
    Emily J. Jaehne, Michelle Corrone, Maarten van den Buuse in Neurobiology
    Protocol 2024
  5. Early detection of autism using digital behavioral phenoty**

    Early detection of autism, a neurodevelopmental condition associated with challenges in social communication, ensures timely access to intervention....

    Sam Perochon, J. Matias Di Martino, ... Geraldine Dawson in Nature Medicine
    Article Open access 02 October 2023
  6. The dynamic state of a prefrontal–hypothalamic–midbrain circuit commands behavioral transitions

    Innate behaviors meet multiple needs adaptively and in a serial order, suggesting the existence of a hitherto elusive brain dynamics that brings...

    Changwan Chen, Mahsa Altafi, ... Alexey Ponomarenko in Nature Neuroscience
    Article Open access 18 March 2024
  7. Correlation of the Karolinska Sleepiness with Behavioral Measures of a Monotonous Bimanual Psychomotor Rest

    Objectives . To assess the objectivity of measurements of the level of drowsiness in subjects using a previously developed monotonous psychomotor...

    A. E. Manaenkov, N. O. Prokhorenko, ... V. B. Dorokhov in Neuroscience and Behavioral Physiology
    Article 01 November 2023
  8. Myrtenol Inhalation Mitigates Asthma-Induced Cognitive Impairments: an Electrophysiological, Behavioral, Histological, and Molecular Study

    Asthma is an inflammatory disorder with significant health problems. It generally affects the lungs but can also impact brain performance via several...

    Khadijeh Esmaeilpour, Elham Jafari, ... Mohammad Amin Rajizadeh in Molecular Neurobiology
    Article 27 December 2023
  9. Prediction of cervical cancer screening: application of the information-motivation-behavioral skills model

    Introduction

    Screening is an effective method for preventing cervical cancer. The present study aimed to determine the predictability of cervical...

    Marzieh Ghasemi, Mitra Savabi-Esfahani, ... Mohammad Satari in BMC Cancer
    Article Open access 19 March 2024
  10. Effects of Chemotherapy on Neuroinflammation, Neuronal Damage, Neurogenesis, and Behavioral Performance in Bone Marrow Transplantation Recipient Mice

    As bone marrow transplant (BMT) is gradually applied to the study of central nervous system (CNS) disease, it is needed to investigate the proper...

    Zhong-Yuan Yu, Man-Yu Xu, ... Yan-Jiang Wang in Neurotoxicity Research
    Article 05 April 2022
  11. Loss of GDE2 leads to complex behavioral changes including memory impairment

    Background

    Alzheimer’s disease (AD) and amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) are debilitating neurodegenerative diseases...

    Daniel Daudelin, Anna Westerhaus, ... Shanthini Sockanathan in Behavioral and Brain Functions
    Article Open access 04 April 2024
  12. Behavioral Analysis of NMDAR Function in Rodents: Tests of Long-Term Spatial Memory

    NMDAR-dependent forms of synaptic plasticity in brain regions like the hippocampus are widely believed to provide the neural substrate for long-term...
    David M. Bannerman, Chris Barkus, Ahmed Eltokhi in NMDA Receptors
    Protocol 2024
  13. The effect of acute crocin on behavioral changes and BDNF expression level in socially isolated rats

    Social isolation is a reliable method used for the induction of depression and psychiatric disorders in rodents. It has been suggested that social...

    Amir-Kamyar Kamaei, Seyedeh-Fatemeh Hosseini, ... Salar Vaseghi in Naunyn-Schmiedeberg's Archives of Pharmacology
    Article 21 November 2023
  14. Cluster-specific associations between the gut microbiota and behavioral outcomes in preschool-aged children

    Background

    The gut microbiota is recognized as a regulator of brain development and behavioral outcomes during childhood. Nonetheless, associations...

    Marcel van de Wouw, Yanan Wang, ... Gerald F. Giesbrecht in Microbiome
    Article Open access 21 March 2024
  15. Task-induced activation transmitted by structural connectivity is associated with behavioral performance

    It is thought that brain structure is the primary determinant of functions of brain regions. For example, cortical areas with functional differences...

    Tianyi Yan, Tiantian Liu, ... **glong Wu in Brain Structure and Function
    Article 20 March 2021
  16. Behavioral read-out from population value signals in primate orbitofrontal cortex

    The primate orbitofrontal cortex (OFC) has long been recognized for its role in value-based decisions; however, the exact mechanism linking value...

    Vincent B. McGinty, Shira M. Lupkin in Nature Neuroscience
    Article 06 November 2023
  17. Ascending neurons convey behavioral state to integrative sensory and action selection brain regions

    Knowing one’s own behavioral state has long been theorized as critical for contextualizing dynamic sensory cues and identifying appropriate future...

    Chin-Lin Chen, Florian Aymanns, ... Pavan Ramdya in Nature Neuroscience
    Article Open access 23 March 2023
  18. Map** the Behavioral Signatures of Shank3b Mice in Both Sexes

    Autism spectrum disorders (ASD) are characterized by social and repetitive abnormalities. Although the ASD mouse model with Shank3b mutations is...

    **g**g Liu, Jialin Ye, ... Feng Wang in Neuroscience Bulletin
    Article Open access 20 June 2024
  19. Behavioral and brain responses to verbal stimuli reveal transient periods of cognitive integration of the external world during sleep

    Sleep has long been considered as a state of behavioral disconnection from the environment, without reactivity to external stimuli. Here we...

    Başak Türker, Esteban Munoz Musat, ... Delphine Oudiette in Nature Neuroscience
    Article Open access 12 October 2023
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