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Simple Behavioral Analysis (SimBA) as a platform for explainable machine learning in behavioral neuroscience
The study of complex behaviors is often challenging when using manual annotation due to the absence of quantifiable behavioral definitions and the...
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Pulsed Focused Ultrasound Reduces Hippocampal Volume Loss and Improves Behavioral Performance in the Kainic Acid Rat Model of Epilepsy
Focused ultrasound (FUS) has the potential to modulate regional brain excitability and possibly aid seizure control; however, effects on behavior of...
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Behavioral Tagging in the Develo** Animal
Infancy is a critical period that shapes an individual’s emotional and developmental trajectory. Indeed, negative early life experiences have been... -
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Administering a Behavioral Test Battery in Rodents
Although animal models cannot broadly represent uniquely human psychiatric or psychological syndromes such as anxiety, depression, or schizophrenia,... -
Early detection of autism using digital behavioral phenoty**
Early detection of autism, a neurodevelopmental condition associated with challenges in social communication, ensures timely access to intervention....
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The dynamic state of a prefrontal–hypothalamic–midbrain circuit commands behavioral transitions
Innate behaviors meet multiple needs adaptively and in a serial order, suggesting the existence of a hitherto elusive brain dynamics that brings...
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Correlation of the Karolinska Sleepiness with Behavioral Measures of a Monotonous Bimanual Psychomotor Rest
Objectives . To assess the objectivity of measurements of the level of drowsiness in subjects using a previously developed monotonous psychomotor...
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Myrtenol Inhalation Mitigates Asthma-Induced Cognitive Impairments: an Electrophysiological, Behavioral, Histological, and Molecular Study
Asthma is an inflammatory disorder with significant health problems. It generally affects the lungs but can also impact brain performance via several...
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Prediction of cervical cancer screening: application of the information-motivation-behavioral skills model
IntroductionScreening is an effective method for preventing cervical cancer. The present study aimed to determine the predictability of cervical...
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Effects of Chemotherapy on Neuroinflammation, Neuronal Damage, Neurogenesis, and Behavioral Performance in Bone Marrow Transplantation Recipient Mice
As bone marrow transplant (BMT) is gradually applied to the study of central nervous system (CNS) disease, it is needed to investigate the proper...
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Loss of GDE2 leads to complex behavioral changes including memory impairment
BackgroundAlzheimer’s disease (AD) and amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) are debilitating neurodegenerative diseases...
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Behavioral Analysis of NMDAR Function in Rodents: Tests of Long-Term Spatial Memory
NMDAR-dependent forms of synaptic plasticity in brain regions like the hippocampus are widely believed to provide the neural substrate for long-term... -
The effect of acute crocin on behavioral changes and BDNF expression level in socially isolated rats
Social isolation is a reliable method used for the induction of depression and psychiatric disorders in rodents. It has been suggested that social...
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Cluster-specific associations between the gut microbiota and behavioral outcomes in preschool-aged children
BackgroundThe gut microbiota is recognized as a regulator of brain development and behavioral outcomes during childhood. Nonetheless, associations...
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Task-induced activation transmitted by structural connectivity is associated with behavioral performance
It is thought that brain structure is the primary determinant of functions of brain regions. For example, cortical areas with functional differences...
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Behavioral read-out from population value signals in primate orbitofrontal cortex
The primate orbitofrontal cortex (OFC) has long been recognized for its role in value-based decisions; however, the exact mechanism linking value...
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Ascending neurons convey behavioral state to integrative sensory and action selection brain regions
Knowing one’s own behavioral state has long been theorized as critical for contextualizing dynamic sensory cues and identifying appropriate future...
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Map** the Behavioral Signatures of Shank3b Mice in Both Sexes
Autism spectrum disorders (ASD) are characterized by social and repetitive abnormalities. Although the ASD mouse model with Shank3b mutations is...
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Behavioral and brain responses to verbal stimuli reveal transient periods of cognitive integration of the external world during sleep
Sleep has long been considered as a state of behavioral disconnection from the environment, without reactivity to external stimuli. Here we...