Search
Search Results
-
Role of syntaxin3 an apical polarity protein in poorly polarized keratinocytes: regulation of asymmetric barrier formations in the skin epidermis
The skin epidermis exhibits an asymmetric structure composed of multilayered keratinocytes and those in the outer layers form two-way physical...
-
Tumor cell-derived asymmetric dimethylarginine regulates macrophage functions and polarization
BackgroundAsymmetric dimethylarginine (ADMA), which is significantly elevated in the plasma of cancer patients, is formed via intracellular recycling...
-
Terminal 10q26.12 deletion is associated with neonatal asymmetric crying facies syndrome: a case report and literature review
BackgroundThe terminal 10q26 deletion syndrome is a clinically heterogeneous disorder without identified genotype–phenotype correlations. We reported...
-
Fragmentation of Different Calcification Growth Patterns in Bicuspid Valves During Balloon Valvuloplasty Procedure
This study focuses on the calcification development and routes of type-1 bicuspid aortic valves based on CT scans and the effect of the unique...
-
Unique asymmetric distribution of phosphatidylserine and phosphatidylethanolamine in Toxoplasma gondii revealed by nanoscale analysis
Toxoplasma gondii is a highly prevalent obligate apicomplexan parasite that is important in clinical and veterinary medicine. It is known that...
-
Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial
BackgroundSystemic treatments for prostate cancer (PC) have significant side effects. Thus, newer alternatives with fewer side effects are urgently...
-
Non-invasive diagnostics of blockage growth in the descending aorta-computational approach
Atherosclerosis causes blockages to the main arteries such as the aorta preventing blood flow from delivering oxygen to the organs. Non-invasive...
-
Asymmetric flow field-flow fractionation as a multifunctional technique for the characterization of polymeric nanocarriers
The importance of polymeric nanocarriers in the field of drug delivery is ever-increasing, and the accurate characterization of their properties is...
-
Inter-arm bone mass and size asymmetries in children tennis players are maturity status specific: a 9-month study on the effects of training time across pubertal change and somatic growth
PurposeBone growth with exercise is best assessed by tennis-induced inter-arm asymmetries. Yet, the effects of training and maturation across puberty...
-
3q27.1 microdeletion causes prenatal and postnatal growth restriction and neurodevelopmental abnormalities
BackgroundOverlap** microdeletions of chromosome 3q26-3q28 have been reported in eight individuals. The common phenotype observed in these...
-
Fibroblast growth factor receptor fusions in cancer: opportunities and challenges
Fibroblast growth factors (FGFs) and their receptors (FGFRs) play critical roles in many biological processes and developmental functions....
-
Dual Asymmetric Centrifugation Efficiently Produces a Poloxamer-Based Nanoemulsion Gel for Topical Delivery of Pirfenidone
This study used dual asymmetric centrifugation (DAC) to produce a topical vehicle for Pirfenidone (Pf; 5-methyl-1-phenyl-2[1H]-pyridone)—a Food and...
-
Investigating the Upstream and Downstream Hemodynamic Boundary Conditions of Healthy and Growth-Restricted Rat Feto-Placental Arterial Networks
The placenta uniquely develops to orchestrate maternal adaptations and support fetal growth and development. The expansion of the feto-placental...
-
Sex- and growth-specific characteristics of small for gestational age infants: a prospective cohort study
BackgroundAsymmetric fetal growth and male sex are both associated with adverse neonatal outcome. However, less is known about the influence of...
-
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours
The protein arginine methyltransferase 5 (PRMT5), which is highly expressed in tumour tissues, plays a crucial role in cancer development. However,...
-
Origin and Development of Cancer Stem Cells
Cancer stem cells (CSCs) have been identified in a vast number of liquid and solid tumors and have been linked to poor patient prognosis and cancer...
-
Hemispheric coupling between structural and functional asymmetries in clinically asymptomatic carotid stenosis with cognitive impairment
Advanced carotid stenosis is a known risk factor for ischemic stroke and vascular dementia, and it is associated with multidomain cognitive...
-
Neurovascular Unit Alterations in the Growth-Restricted Newborn Are Improved Following Ibuprofen Treatment
The develo** brain is particularly vulnerable to foetal growth restriction (FGR) and abnormal neurodevelopment is common in the FGR infant ranging...
-
Self-assembled polyelectrolyte complexes of chitosan and fucoidan for sustained growth factor release from PRP enhance proliferation and collagen deposition in diabetic mice
Diabetic wound management is a serious health care challenge due to higher rates of relapse, expensive treatment approaches, and poor healing...
-
Combination of human endothelial colony-forming cells and mesenchymal stromal cells exert neuroprotective effects in the growth-restricted newborn
The foetal brain is particularly vulnerable to the detrimental effects of foetal growth restriction (FGR) with subsequent abnormal neurodevelopment...
