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In Vivo and In Vitro Analysis of Toxicity of a Prospective Magnetic Resonance Contrast Agent Based on Arabinogalactan and Gadolinium Nanocomposite
We studied the cytotoxic effect of gadolinium nanocomposite on cultured mouse fibroblasts 3T3-SV40 and histological changes in the liver tissue of...
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Identification of intracellular activation mechanism of rhamnogalacturonan-I type polysaccharide purified from Panax ginseng leaves in macrophages and roles of component sugar chains on activity
This study aimed to investigate the mechanisms underlying intracellular signaling pathways in macrophages in relation to the structural features of...
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Exploring Decaprenylphosphoryl-β-d-Ribose 2′-Epimerase 1 (DprE1): A Target for Anti-tubercular Drugs
Decaprenylphosphoryl-β-d-ribose 2′-epimerase 1(DprE1)DprE1Decaprenylphosphoryl-β-D-ribose 2’-Epimerase 1 is a new and competent target that could be...
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Resistance in Tuberculosis: Molecular Mechanisms and Modulation
Since the time of years following World War II, tuberculosis (TB) has become a treatable disease due to the discoveryDiscoverydrug of...
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Atorvastatin calcium inclusion complexation with polysaccharide arabinogalactan and saponin disodium glycyrrhizate for increasing of solubility and bioavailability
The aim of the present investigation was to enhance the solubility and dissolution of atorvastatin calcium (ATV), a poorly water-soluble drug with...
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Drug Resistance in Tuberculosis: Mechanisms, Diagnosis, New Responses, and the Need for an Integrated Approach
Despite the global efforts done in recent decades, tuberculosis (TB)’s impact on global public healthPublic health remains substantial. In recent...
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Important Targets and Inhibitors of Mycobacterium tuberculosis
Tuberculosis (TB) is a global health issue. Millions of TB-infected patients remain undiagnosed, untreated, or improperly treated, leading to...
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From Observing Children in Traditional Upbringing to Concepts of Health
Studies in rural areas of develo** countries and the farm studies have generated a rich texture of investigations on how traditional lifestyles in...
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Computational Identification of Citrus reticulata L. microRNAs and the Cis-Acting Regulatory Elements to Predict the Expression Probability of Their Respective MIR Genes
MicroRNA(miRNA), a small non-coding class of RNA that regulates the gene expression, is conserved among several plant species. In the present study,...
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Multiomics Integration of Tuberculosis Pathogenesis
Advances in high-throughput technology have made it possible to quantitatively monitor changes in multiple sets of biological molecules under...
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Targeting vimentin: a multifaceted approach to combatting cancer metastasis and drug resistance
This comprehensive review explores vimentin as a pivotal therapeutic target in cancer treatment, with a primary focus on mitigating metastasis and...
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Medicinal Plants in Targeting Tuberculosis II
Tuberculosis is a highly contagious infectious disease triggered by Mycobacterium tuberculosis, which is widely spread by aerosol. The major site of...
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The Correlation of Microbiota and Host Epigenome in Tuberculosis
Tuberculosis (TB) infection still represents a relevant global health issue affecting millions of patients worldwide, although some may remain...
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Targeting Molecular and Cellular Mechanisms in Tuberculosis
The major global problems are the prevalence rate of Mycobacterium tuberculosis (Mtb) and processes of resistance against continuing therapy. The...
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Middle Eastern Diets as a Potential Source of Immunomodulators
The immune system is a highly developed and complex system. Its optimal functioning is critical to human health, being responsible for safeguarding...
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The Itemization of Variations in the Tassel-Ear Mutant and Wild Maize (Zea mays L.) Plants: II. Changes in Epigenetic Gene Profile
AbstractMany mutations and phenotypic variations, which often fail to be explained by nucleotide changes with hereditary consequences, are supported...
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Analysis of the Diversity and Functional Potential of Bacterial Communities in Tuberculomas
The dynamics of lung microbiota in tuberculosis remains poorly understood. Sequencing of variable regions of the 16S rRNA gene from surgically...
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Pistacia lentiscus L. (Anacardiaceae)
A small tree[aut] , native to Mediterranean region countries. Mastic gum (oleogum resin) is mentioned in the works of Herodotus, Dioscorides and...