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Alzheimer’s Disease Methods and Protocols
This volume explores the latest techniques used to study the human brain towards understanding Alzheimer’s Disease and related neurodegenerative...
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Alzheimer’s Disease Research What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift
This book highlights the key phases and central findings of Alzheimer’s Disease research since the introduction of the label ‘Alzheimer’s Disease’ in...
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Alzheimer’s Disease
Alzheimer’s disease is a dramatic pathological occurrence for the patient, his family, caregivers and doctors.
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Biomarkers for Alzheimer’s Disease Drug Development
This fully updated volume provides an up-to-date and comprehensive overview of the current state of technologies hel** to accelerate Alzheimer’s...
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Metabolic Disease and Alzheimer’s Disease
Age-related diseases (ARDs) include inflammatory atherosclerosis and cardiovascular disease in coronary artery disease (CAD), hypertension, type 2...
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Deciphering Drug Targets for Alzheimer’s Disease
This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on...
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Alzheimer’s Disease Research After 1945: The Recommencement
Scientific publishing platforms such as PubMed feature an overwhelming number of entries on “Alzheimer’s disease” compared to other human...
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The Glutamatergic Hypothesis of Alzheimer’s Disease
Glutamate (L-glutamate, L-glutamic acid) is an amino acid and building block of peptides and proteins. In addition, glutamate is the most abundant...
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Epigenetic Therapy for Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with no effective treatments. Increasing evidence suggests that the epigenetic...
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Neuroinflammation in Alzheimer’s Disease
Alzheimer’s disease (AD) is one of the significant progressive disorders of the brain, which lead to the destruction of memory and cognitive power in...
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Pathophysiology and Management Approaches in Alzheimer’s Disease
Alzheimer’s disease is recognized as a progressive multifarious neurodegenerative disorder that is pathologically characterized by the deposition of...
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Introduction to Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive neurodegenerative ailment associated with intracellular amyloid aggregates and extracellular...
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Age, sex and Alzheimer’s disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer’s patients
BackgroundAging and sex are major risk factors for develo** late-onset Alzheimer’s disease. Compared to men, women experience worse...
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Animal Model of Aluminum-Induced Alzheimer’s Disease
The lack of a satisfactory animal model for Alzheimer’s disease (AD) has limited progress in understanding the pathogenesis of the disease and...
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Drug Delivery Strategies in Alzheimer’s Disease
Over the past few decades, a concern over neurodegenerative disorders is growing proportionately with age, changing lifestyles, hereditary...
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Biomarkers for Alzheimer’s Disease
Alzheimer’s disease is a neurodegenerative disease, which affects intellectually is frequently observed in elderly generations and genetically linked...
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Magnetic Resonance Spectroscopy (MRS) in Alzheimer’s Disease
MRS is a noninvasive technique to measure different metabolites in the brain. Changes in the levels of certain metabolites can be used as surrogate...
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Lipid Profiling in Alzheimer’s Disease
The human brain is the organ with the most lipids after adipose tissues. The rich heterogeneity of the neural lipidome is being actively investigated...
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Cathepsin B abundance, activity and microglial localisation in Alzheimer’s disease-Down syndrome and early onset Alzheimer’s disease; the role of elevated cystatin B
Cathepsin B is a cysteine protease that is implicated in multiple aspects of Alzheimer’s disease pathogenesis. The endogenous inhibitor of this...
