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Nutraceuticals for Alzheimer's Disease: A Promising Therapeutic Approach
This book reviews the potential effect of diet modification, lipids, and carbohydrate consumptions, vitamin supplementation, antioxidants, and...
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Natural Product-based Synthetic Drug Molecules in Alzheimer's Disease Therapeutic & Theranostic Agents
This book illustrates the importance of natural products as the source for the development of novel drugs for the treatment of neurodegenerative... -
The network pharmacology study and molecular docking to investigate the potential mechanism of Acoritataninowii Rhizoma against Alzheimer's Disease
Alzheimer's Disease is considered as an insidious neurodegenerative progressive disease but its pathogenesis has not been elucidated....
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Morphometric analysis of medial temporal lobe subregions in Alzheimer's disease using high-resolution MRI
The spread pattern of progressive degeneration seen in Alzheimer's disease (AD) to small-scale medial temporal lobe subregions is critical for early...
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Does Inflammation Play a Major Role in the Pathogenesis of Alzheimer's Disease?
Alzheimer's disease (AD) is a neurodegenerative disease leading to dementia for which no effective medicine exists. Currently, the goal of therapy is...
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Targeting Novel microRNAs in Develo** Novel Alzheimer's Disease Treatments
Alzheimer's disease (AD) is considered a multifactorial disease and a significant cause of dementia during aging. This neurodegenerative disease...
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Intestinal Flora Affect Alzheimer's Disease by Regulating Endogenous Hormones
Alzheimer's disease (AD) is a central nervous system disease that can lead to cognitive impairment and progressive memory loss. An increasing number...
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Intermittent fasting and Alzheimer's disease—Targeting ketone bodies as a potential strategy for brain energy rescue
Alzheimer's disease (AD) lacks effective clinical treatments. As the disease progresses, the cerebral glucose hypometabolism that appears in the...
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Neuroprotective Effect of Chlorogenic Acid in an Animal Model of Sporadic Alzheimer's Disease Induced by Streptozotocin
Alzheimer's Disease is a degenerative neurological condition which leads to a decline in memory and cognitive function. Chlorogenic Acid (CGA)...
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Proteomics revealed an association between ribosome-associated proteins and amyloid beta deposition in Alzheimer's disease
Most scholars believe that amyloid-beta (Aβ) has the potential to induce apoptosis, stimulate an inflammatory cascade, promote oxidative stress and...
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H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFκB signaling pathway
Cellular senescence serves as a fundamental and underlying activity that drives the aging process, and it is intricately associated with numerous...
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miR-34a/TAN1/CREB Axis Engages in Alleviating Oligodendrocyte Trophic Factor-Induced Myelin Repair Function and Astrocyte-Dependent Neuroinflammation in the Early Stages of Alzheimer's Disease: The Anti-Neurodegenerative Effect of Treadmill Exercise
Reduced myelin stability observed in the early stages of Alzheimer's disease leads to spatial learning and memory impairment. Exercise has been shown...
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Molecular dynamics exploration of Lupenone: therapeutic implications for glioblastoma multiforme and alzheimer's amyloid beta pathogenesis
Neuro-oncological and neurodegenerative disorders, represented paradigmatically by glioblastoma and Alzheimer's disease, respectively, persist as...
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The present and future of minimally invasive methods for Alzheimer's disease diagnosis
Objective and methodsInvasive and noninvasive methods for diagnosing Alzheimer's disease (AD) are discussed and efforts to test less invasively are...
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Sha** the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models
The transcellular propagation of the aberrantly modified protein tau along the functional brain network is a key hallmark of Alzheimer's disease and...
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Bioinformatics investigation on blood-based gene expressions of Alzheimer's disease revealed ORAI2 gene biomarker susceptibility: An explainable artificial intelligence-based approach
The progressive, chronic nature of Alzheimer's disease (AD), a form of dementia, defaces the adulthood of elderly individuals. The pathogenesis of...
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Saffron as a promising therapy for diabetes and Alzheimer's disease: mechanistic insights
The prevalence of both Alzheimer's disease (AD) and diabetes mellitus is increasing with the societies' aging and has become an essential social...
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Primate brain pattern-based automated Alzheimer's disease detection model using EEG signals
Electroencephalography (EEG) may detect early changes in Alzheimer's disease (AD), a debilitating progressive neurodegenerative disease. We have...
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Insulin Delivery to the Brain via the Nasal Route: Unraveling the Potential for Alzheimer's Disease Therapy
This comprehensive review delves into the potential of intranasal insulin delivery for managing Alzheimer's Disease (AD) while exploring the...
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Automatic Detection of Alzheimer's Disease using Deep Learning Models and Neuro-Imaging: Current Trends and Future Perspectives
Deep learning algorithms have a huge influence on tackling research issues in the field of medical image processing. It acts as a vital aid for the...