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Characterization of yam mosaic viruses from Brazil reveals a new phylogenetic group and possible incursion from the African continent
Yam ( Dioscorea spp.) is an important crop for smallholder farmers in the Northeast region of Brazil. Wherever yam is grown, diseases caused by yam...
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Viral hepatitis associated hepatocellular carcinoma on the African continent, the past, present, and future: a systematic review
BackgroundHepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in Africa. In Africa, the major causes of HCC include...
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Evaluation of Risk-Based Approaches to the Registration of Medicines: Current Status Among African Regulatory Authorities
BackgroundDespite the worldwide need for increased access to safe and effective medicines, there is a lack of innovative medicines in many low- to...
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Establishing African genomics and bioinformatics programs through annual regional workshops
The African BioGenome Project (AfricaBP) Open Institute for Genomics and Bioinformatics aims to overcome barriers to capacity building through its...
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Perspectives of African stakeholders on gene drives for malaria control and elimination: a multi-country survey
BackgroundGene drive modified mosquitoes (GDMMs) have the potential to address Africa’s persistent malaria problem, but are still in early stages of...
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High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response
How human genetic variation contributes to vaccine effectiveness in infants is unclear, and data are limited on these relationships in populations...
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Building the capacity of West African countries in Aedes surveillance: inaugural meeting of the West African Aedes Surveillance Network (WAASuN)
Arboviral diseases such as dengue, Zika and chikungunya transmitted by Aedes mosquitoes have been reported in 34 African countries. Available data...
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Develo** African arbovirus networks and capacity strengthening in arbovirus surveillance and response: findings from a virtual workshop
This meeting report presents the key findings and discussion points of a 3-h virtual workshop, held on 21 September 2022, and organized by the...
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Human African Trypanosomiasis (HAT)
Human African Trypanosomiasis (HAT) found only in sub-Saharan Africa is caused by the parasite Trypanosoma brucei, which is transmitted by tsetse... -
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Human African Trypanosomiasis: The Smoldering Scourge of Africa
Human African trypanosomiasis (HAT) or slee** sickness is a parasitic disease caused by trypanosomes, which are transmitted by tsetse flies. Two... -
Human African Trypanosomiasis: The Smoldering Scourge of Africa
Human African trypanosomiasis (HAT) or slee** sickness is a parasitic disease caused by trypanosomes, which are transmitted by tsetse flies. Two... -
Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction
We performed genome-wide association studies of breast cancer including 18,034 cases and 22,104 controls of African ancestry. Genetic variants at 12...
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Prevalence of the protective OAS1 rs10774671-G allele against severe COVID-19 in Moroccans: implications for a North African Neanderthal connection
The clinical presentation of COVID-19 shows high variability among individuals, which is partly due to genetic factors. The OAS1/2/3 cluster has been...
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Knowledge of African Traditional Medicine System: Immunomodulation
African traditional medicine is one of the oldest forms of health-care system in the continent that has continued to be relevant. It is usually... -
High mortality in free-ranging wild boars associated with African swine fever virus in India
The present study focuses on the pathological and molecular characterization of African swine fever virus (ASFV) associated with an outbreak in wild...
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Medicines Regulatory Science Expertise in Africa: Workforce Capacity Development and Harmonisation Activities Towards the Establishment of the African Medicines Agency
The medicines regulatory landscape in Africa is undergoing transformation with at least two countries having National Medicines Regulatory...
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Contributions from a Land Down Under: The Arid Continent
The Australian continent separated from Gondwana about 70 million years ago, carrying flora and fauna that later evolved into many unique species.... -
Coinfections of African swine fever virus, porcine circovirus 2 and 3, and porcine parvovirus 1 in swine in Nigeria
As pig production increases in Africa, it is essential to identify the pathogens that are circulating in the swine population to assess pig welfare...