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Evidence of innate immune dysfunction in first-episode psychosis patients with accompanying mood disorder
BackgroundInflammation and increases in inflammatory cytokines are common findings in psychiatric disorders such as schizophrenia (SCZ), bipolar...
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Affective temperaments of Lebanese patients with schizophrenia: comparison by gender and severity of psychosis
ObjectivesOur aim in this study was to identify affective temperament differences utilizing the TEMPS-A in a large sample size of Lebanese patients...
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Cerebellar Effects on Abnormal Psychomotor Function Are Mediated by Processing Speed in Psychosis Spectrum
Psychomotor disturbance has been identified as a key feature of psychotic disorders, with motor signs observed in upwards of 66% of unmedicated,...
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Artificial Intelligence: The Future of Individualized and Effective Healthcare Approach for Psychosis
Every year, the incidence and prevalence of mental diseases rise. There has been a spike in drug usage, loneliness, and suicidal ideation because of...
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Structural Features of the Brain in Juvenile Depression with Clinical High Risk of Psychosis
Objectives . To identify the structural features of the gray matter of the cerebral cortex in patients with depression at clinical high risk of...
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Atypical cerebellar activity and connectivity during affective touch in adults with skin-picking disorder
Excessive touching and picking of one’s skin are core symptoms of skin-picking disorder (SPD). Previous research has shown that patients with SPD...
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A systematic review and meta-analysis of synthetic cathinone use and psychosis
RationaleSynthetic cathinones (SC), commonly referred to as “bath salts”, are stimulants resembling the natural alkaloid cathinone found in the khat ...
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Heterogeneity of clinical symptomatology in pediatric patients at clinical high risk for psychosis
ObjectiveWidespread use of diagnostic tools like the Structured Interview for Prodromal Symptoms (SIPS) has highlighted that youth at Clinical High...
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The Cerebellar Cognitive Affective Syndrome and the Neuropsychiatry of the Cerebellum
Cognitive and limbic functions are represented in the cerebellar posterior lobe and vermis. Lesions of these areas produce dysmetria of thought,...
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Cognitive Dysfunction as a Risk Factor for Psychosis
The current chapter summarizes recent evidence for cognition as a risk factor for the development of psychosis, including the range of cognitive...
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A Pilot Study of Adolescents with Psychotic Experiences: Potential Cerebellar Circuitry Disruption Early Along the Psychosis Spectrum
A berrant connectivity in the cerebellum has been found in psychotic conditions such as schizophrenia corresponding with cognitive and motor deficits...
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Sex Differences in Psychosis: Focus on Animal Models
Most psychiatric illnesses, such as schizophrenia, show profound sex differences in incidence, clinical presentation, course, and outcome....
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Emotional and Affective Disorders in Cognitive Aging
The increased aging population who have aging-related diseases poses a serious challenge to health services, including mental health services. Due to...
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Characteristics of very late-onset schizophrenia-like psychosis as prodromal dementia with Lewy bodies: a cross-sectional study
BackgroundThis study aimed to identify cases of potential prodromal DLB in very late-onset schizophrenia-like psychosis (VLOSLP), using indicative...
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Ferdinando Rossi Lecture: the Cerebellar Cognitive Affective Syndrome—Implications and Future Directions
The notion that the cerebellum is devoted exclusively to motor control has been replaced by a more sophisticated understanding of its role in...
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The Cerebellar Cognitive Affective Syndrome and the Neuropsychiatry of the Cerebellum
The traditional teaching that the cerebellum is purely a motor control device no longer appears to be valid, if indeed it ever was. Current evidence...
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Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity
Risk for psychosis begins to accumulate as early as the fetal period through exposure to obstetric complications like fetal hypoxia, maternal stress,...
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Sex difference in cerebrospinal fluid/blood albumin quotients in patients with schizophreniform and affective psychosis
BackgroundThe importance of cerebrospinal fluid (CSF) diagnostics for psychiatry is growing. The CSF/blood albumin quotient (Q Alb ) is considered to...
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Effects of the COVID-19 Pandemic on the Occurrence and Course of Mental Disorders in Elderly People
Objectives . To study the impact of COVID-19 on the occurrence and course of mental illness in hospitalized elderly patients. Materials and methods ....
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Drug Therapy of Psychosis and Mania
Psychosis and mania are psychiatric disorders wherein there is loss of insight for the affected patients. While the exact pathophysiology behind...