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Operational encoding enhances action knowledge integration: insights from event-related potential analysis
In this study, we conducted an examination of knowledge integration concerning action information and assessed the impact of operational on this...
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Necroptosis inhibitors: mechanisms of action and therapeutic potential
Necroptosis is a type of programmed cell death that is morphologically similar to necrosis. This type of cell death is involved in various...
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Antiviral Natural Products, Their Mechanisms of Action and Potential Applications as Sanitizers and Disinfectants
Plant extracts, natural products and plant oils contain natural virucidal actives that can be used to replace active ingredients in commercial...
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The electrical restitution of the non-propagated cardiac ventricular action potential
Sudden changes in pacing cycle length are frequently associated with repolarization abnormalities initiating cardiac arrhythmias, and physiologists...
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Neuronal Differentiation: Focus on the Action Potential
In this chapter, the author has focused on differentiation of a key neuronal property – electrical excitability, for which the action potential (AP)...
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Neuronal Differentiation: Focus on the Action Potential
In this chapter, the author has focused on differentiation of a key neuronal property – electrical excitability, for which the action potential (AP)...
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Neuroprotective Action of Selected Natural Drugs Against Neurological Diseases and Mental Disorders: Potential Use Against Radiation Damage
Exposure to radiation, ionizing and non-ionizing radiation, is a significant concern in modern society. The brain is the organ that is most sensitive...
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FBXW7 in breast cancer: mechanism of action and therapeutic potential
Breast cancer is one of the frequent tumors that seriously endanger the physical and mental well-being in women. F-box and WD repeat...
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Evoked compound action potential (ECAP)-controlled closed-loop spinal cord stimulation in an experimental model of neuropathic pain in rats
BackgroundPreclinical models of spinal cord stimulation (SCS) are lacking objective measurements to inform translationally applicable SCS parameters....
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Diarylheptanoids/sorafenib as a potential anticancer combination against hepatocellular carcinoma: the p53/MMP9 axis of action
Hepatocellular carcinoma (HCC) is a serious and potentially fatal form of cancer associated with liver damage. New anticancer drugs are increasingly...
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Superior anti-pulmonary viral potential of Natrialba sp. M6-producing surfactin and C50 carotenoid pigment with unveiling its action modes
BackgroundRespiratory viruses, particularly adenoviruses (ADV), influenza A virus (e.g., H1N1), and coronaviruses (e.g., HCoV-229E and SARS-CoV-2)...
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Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
Chemokines belong to the family of cytokines with chemoattractant properties that regulate chemotaxis and leukocyte migration, as well as the...
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Regulation of Axon Initial Segment Diameter by COUP-TFI Fine-tunes Action Potential Generation
The axon initial segment (AIS) is a specialized structure that controls neuronal excitability via action potential (AP) generation. Currently, AIS...
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( −)-Epicatechin and cardiometabolic risk factors: a focus on potential mechanisms of action
This review summarizes experimental evidence on the beneficial effects of ( −)-epicatechin (EC) attenuating major cardiometabolic risk factors, i.e.,...
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Independent inhibitory control mechanisms for aggressive motivation and action
Social behaviors often consist of a motivational phase followed by action. Here we show that neurons in the ventromedial hypothalamus ventrolateral...
