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Psychiatric Vulnerability, Mood, and Anxiety Disorders Tests and Models in Mice and Rats
This volume looks at classic and novel methods currently used by researchers to understand mood and anxiety disorders and foster precision medicine....
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Developments in the classification and nomenclature of arthropod-infecting large DNA viruses that contain pif genes
Viruses of four families of arthropod-specific, large dsDNA viruses (the nuclear arthropod large DNA viruses, or NALDVs) possess homologs of genes...
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Adjustable prosthetic sockets: a systematic review of industrial and research design characteristics and their justifications
BackgroundThe prosthetic socket is a key component that influences prosthesis satisfaction, with a poorly fitting prosthetic socket linked to...
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Biological Synthesis of Nanoparticles: Bacteria
Bacteria are unicellular prokaryotic microorganisms that provide numerous advantages over the eukaryotic systems in green synthesis of nanoparticles....
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Fear learning induces synaptic potentiation between engram neurons in the rat lateral amygdala
The lateral amygdala (LA) encodes fear memories by potentiating sensory inputs associated with threats and, in the process, recruits 10–30% of its...
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Complete genome sequence of a novel dsRNA virus from the phytopathogenic fungus Fusarium oxysporum
Fusarium oxysporum is a widespread plant pathogen that causes fusarium wilt and fusarium root rot in many economically significant crops. Here, a...
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A Bayesian Approach to Kinetic Modeling of Accelerated Stability Studies and Shelf Life Determination
Kinetic modeling of accelerated stability data serves an important purpose in the development of pharmaceutical products, providing support for shelf...
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A growth-accommodating implant for paediatric applications
Medical implants of fixed size cannot accommodate normal tissue growth in children and often require eventual replacement or—in some cases—removal,...
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Clinical landscape of macrophage-reprogramming cancer immunotherapies
Tumour-associated macrophages (TAMs) sustain a tumour-supporting and immunosuppressive milieu and therefore aggravate cancer prognosis. To modify TAM...
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Aging, frailty, and design of built environments
Before develo** agriculture, herding or metallurgy, humans occupied most of the world. Multiple socioculturally-based responses supported their...
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Nanocapsules
Nanoparticles are structures of sizes ranging from 1 to 100 nm in at least one dimension. Nanocapsules along with nanospheres are the most common...
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Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Most transcriptome-wide association studies (TWASs) so far focus on European ancestry and lack diversity. To overcome this limitation, we aggregated...
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Personalized Numerical Cardiovascular Model with Weight Growth for Evaluating Pediatric Left Ventricular Assist Devices: Derivation from an Experimental Mock Circulatory Loop
Pediatric patients with heart failure have limited treatment options because of a shortage of donor hearts and compatible left ventricular assist...
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Letermovir for CMV Prophylaxis in Very High-Risk Pediatric Hematopoietic Stem Cell Transplantation Recipients for Inborn Errors of Immunity
The burden of CMV infection and disease is important in pediatric hematopoietic stem cell transplantation (HSCT), notably in the subgroup of patients...
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Fundamental Neurocardiology: The Intracardiac Nervous System
Cardiac output is controlled by the autonomic nervous system to meet continually changing demands for the perfusion of systemic vascular beds....
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Exploring novel dilazep derivatives as hENT1 inhibitors and potentially covalent molecular tools
The human equilibrative nucleoside transporter 1 (SLC29A1, hENT1) is a solute carrier that modulates the passive transport of nucleosides and...
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The ankle dorsiflexion kinetics demand to increase swing phase foot-ground clearance: implications for assistive device design and energy demands
BackgroundThe ankle is usually highly effective in modulating the swing foot’s trajectory to ensure safe ground clearance but there are few reports...
