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Nanodelivery in Gene Therapy
Gene therapy stands as a revolutionary approach in medicine, aiming to rectify genetic abnormalities by introducing therapeutic genes or regulating...
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Gene Therapy and Cardiovascular Diseases
Cardiovascular diseases (CVDs) are the leading causes of death globally and urgently require new novel therapeutic strategies. Gene therapy is the...
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Gene Expression and Chromatin
In this chapter, principles of gene expression are discussed. An essential condition that a gene can be expressed, i.e., transcribed into RNA, is...
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Gene Therapy in Molecular Biology and Drug Delivery
The objective of gene therapy is to manipulate/modify the gene expression or modify living cell characteristics for therapeutic utilization. It aims...
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Gene Therapy of Cancer Methods and Protocols
This third edition provides new and updated chapters on gene therapeutic strategies of cancer. Chapters guide readers through suicide and oncolytic...
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Muscular Dystrophy: Mutations in the Dystrophin Gene
Muscular dystrophy (MD) is a heterogeneous group of genetic disorders characterized by progressive muscle degeneration and weakness, leading to...
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Immune Gene Therapy of Cancer
Cancer is the second global cause of mortality. Conventional treatments, such as chemotherapy and radiotherapy, have not provided desirable...
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Dissecting the Immune System through Gene Regulation
The immune system plays a dual role in human health, functioning both as a protector against pathogens and, at times, as a contributor to disease....
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Virus-Induced Heritable Gene Editing in Plants
Gene editing using clustered, regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) nuclease is an excellent tool for...
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Gene Editing in Hematopoietic Stem Cells
Hematopoietic stem cells (HSCs) can be isolated and collected from the body, genetically modified, and expanded ex vivo. The invention of innovative...
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Gene Delivery to Chondrocytes
Delivering genes to chondrocytes offers new possibilities both clinically, for treating conditions that affect cartilage, and in the...
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Gene–Nutrient Interaction and Cancer Prevention
Research on carcinogenesis has provided a plethora of knowledge regarding cancer. Cancer cells are the product of numerous genetic abnormalities that...
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Gene Editing Tool for Neurodegenerative Diseases
Neurodegenerative diseases (NDs) encompass a heterogeneous group of disorders characterized by the progressive degeneration and death of neural...
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Optical Control of Mononegavirus Gene Expression and Replication
Mononegaviruses are promising tools as oncolytic and transgene vectors for gene therapy and regenerative medicine. However, when mononegaviruses are...
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Amyotrophic Lateral Sclerosis-Related Gene Interactions with Fat Mass and Obesity-Associated Gene
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder, characterized by rapid progressive paralysis and death within a few...
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Amyotrophic Lateral Sclerosis-Related Gene Interactions with Fat Mass and Obesity-Associated Gene
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder, characterized by rapid progressive paralysis and death within a few...