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Showing 161-180 of 1,672 results
  1. Ethyl acrylate: influence of sex or atopy on perceptual ratings and eye blink frequency

    Occupational exposure limits (OELs) are derived for protection from health hazards, assuming that exposed subjects are healthy adult workers. Whether...

    Kirsten Sucker, Frank Hoffmeyer, ... Thomas Brüning in Archives of Toxicology
    Article 11 September 2019
  2. Hyperglycemia enhances brain susceptibility to lipopolysaccharide-induced neuroinflammation via astrocyte reprogramming

    Hyperglycemia has been shown to modulate the immune response of peripheral immune cells and organs, but the impact of hyperglycemia on...

    Kyung-Seo Lee, Sung-Hyun Yoon, ... Je-Wook Yu in Journal of Neuroinflammation
    Article Open access 27 May 2024
  3. Systematic characterization of a non-transgenic Aβ1–42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice

    Background

    The amyloid- β (A β ) cascade is one of the most studied theories linked to AD. In multiple models, A β accumulation and dyshomeostasis have...

    Raquel Jiménez-Herrera, Ana Contreras, ... Lydia Jiménez-Díaz in Biology of Sex Differences
    Article Open access 16 September 2023
  4. Visual–auditory interactions on explicit and implicit information processing

    Interactions among sensory information are important for generating a coherent percept of the external world. Facilitation and inhibition effects in...

    L. Y. Lo, C. C. Lai in Cognitive Processing
    Article 10 February 2022
  5. Tetramethylpyrazine Attenuates Cognitive Impairment Via Suppressing Oxidative Stress, Neuroinflammation, and Apoptosis in Type 2 Diabetic Rats

    Cognitive dysfunction is an important complication observed in type 2 diabetes mellitus (T2DM) patients. Tetramethylpyrazine (TMP) is known to...

    Jatinder Dhaliwal, Navneet Dhaliwal, ... Kanwaljit Chopra in Neurochemical Research
    Article 04 June 2022
  6. Memory Storage in Distributed Engram Cell Ensembles

    One of the most fascinating aspects of the brain is its ability to acquire new information from experience and retain it over time as memory. The...
    Ying Zhang, Dheeraj S. Roy in Engrams
    Chapter 2024
  7. Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials

    Cannabis use disorder (CUD) is widespread, and there is no pharmacotherapy to facilitate its treatment. AEF0117, the first of a new pharmacological...

    Margaret Haney, Monique Vallée, ... Pier Vincenzo Piazza in Nature Medicine
    Article Open access 08 June 2023
  8. TREM2 mediates physical exercise-promoted neural functional recovery in rats with ischemic stroke via microglia-promoted white matter repair

    Background

    The repair of white matter injury is of significant importance for functional recovery after ischemic stroke, and the up-regulation of...

    **ghui Xu, Liying Zhang, ... **quan Hu in Journal of Neuroinflammation
    Article Open access 25 February 2023
  9. Kapβ2 Inhibits Perioperative Neurocognitive Disorders in Rats with Mild Cognitive Impairment by Reversing the Nuclear-Cytoplasmic Mislocalization of hnRNPA2/B1

    Harmful stimuli trigger mutations lead to uncontrolled accumulation of hnRNPA2/B1 in the cytoplasm, exacerbating neuronal damage. Kapβ2 mediates the...

    Miao Zhang, Feiyu Jia, ... Haiyun Wang in Molecular Neurobiology
    Article 16 December 2023
  10. Clinical and Preclinical Evidence for M1 Muscarinic Acetylcholine Receptor Potentiation as a Therapeutic Approach for Rett Syndrome

    Rett syndrome (RTT) is a neurodevelopmental disorder that is characterized by developmental regression, loss of communicative ability, stereotyped...

    Mackenzie Smith, Bright Arthur, ... Rocco G. Gogliotti in Neurotherapeutics
    Article Open access 07 June 2022
  11. Sensory Systems of the African Naked Mole-Rat

    Naked mole-rats share some sensory characteristics with other subterraneans, including lack of object vision, retention of the ability to entrain...
    Emily N. Vice, Samantha Lagestee, ... Thomas J. Park in The Extraordinary Biology of the Naked Mole-Rat
    Chapter 2021
  12. Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer’s disease mice

    Background

    A growing body of epidemiological literature indicates that particulate matter (PM) air pollution exposure is associated with elevated...

    Katrina Jew, Denise Herr, ... Alison Elder in Particle and Fibre Toxicology
    Article Open access 26 November 2019
  13. Fluorescent Light Opening New Horizons

    In this final Chapter we try to evaluate the most rapidly progressing application areas of fluorescence sensing technologies and to make prognosis...
    Alexander P. Demchenko in Introduction to Fluorescence Sensing
    Chapter 2023
  14. Antidepressant activity of pharmacological and genetic deactivation of the small-conductance calcium-activated potassium channel subtype-3

    Rationale

    The voltage-insensitive, small-conductance calcium-activated potassium (SK) channel is a key regulator of neuronal depolarization and is...

    Mina G. Nashed, Shannon Waye, ... José N. Nobrega in Psychopharmacology
    Article 04 January 2022
  15. Sex Differences in Social Cognition

    In this review we explore the sex differences underlying various types of social cognition. Particular focus will be placed on the behaviors of...
    Pietro Paletta, Noah Bass, ... Elena Choleris in Sex Differences in Brain Function and Dysfunction
    Chapter 2022
  16. BDNF Augmentation Using Riluzole Reverses Doxorubicin-Induced Decline in Cognitive Function and Neurogenesis

    Cancer-related cognitive impairment (CRCI) considerably affects the quality of life of millions of cancer survivors. Brain-derived neurotrophic...

    Manal T. Usmani, Robert P. Krattli Jr., ... Alexandre Chan in Neurotherapeutics
    Article Open access 31 January 2023
  17. Integrated Transcriptomics and Network Analysis Identified Altered Neural Mechanisms in Frontal Aging Brain-Associated Alzheimer’s Disease

    Alzheimer’s disease (AD) is the most common neurodegenerative disease. The late stage of AD typically develops after 60 years of age and AD...

    Suthipong Chujan, Wanida Cholpraipimolrat, Jutamaad Satayavivad in Biochemical Genetics
    Article 07 November 2023
  18. Modulation of olfactory-driven behavior by metabolic signals: role of the piriform cortex

    Olfaction is one of the major sensory modalities that regulates food consumption and is in turn regulated by the feeding state. Given that the...

    Dolly Al Koborssy, Brigitte Palouzier-Paulignan, ... Andrée Karyn Julliard in Brain Structure and Function
    Article 13 October 2018
  19. Hippocampal Engrams and Contextual Memory

    Memories are not formed in a vacuum and often include rich details about the time and place in which events occur. Contextual stimuli promote the...
    Krithika Vasudevan, James E. Hassell, Stephen Maren in Engrams
    Chapter 2024
  20. The functional relevance of olfactory marker protein in the vertebrate olfactory system: a never-ending story

    Olfactory marker protein (OMP) was first described as a protein expressed in olfactory receptor neurons (ORNs) in the nasal cavity. In particular,...

    Michele Dibattista, Dolly Al Koborssy, ... Johannes Reisert in Cell and Tissue Research
    Article 15 January 2021
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